The National Science Foundation (NSF) awarded a $634,420 project grant under its Integrative Activities (CFDA 47.083) program to the University of Alabama in Huntsville (UAH) to acquire an advanced confocal microscope system. This high-speed, high-resolution microscope will enable innovative and multidisciplinary research across various scientific disciplines, including neuroscience, microbiology, cell biology, and materials science. The microscope will be integrated into classes and student...
This federal Project Grant from the National Science Foundation (NSF) Office of Integrative Activities provides $276,998 to the University of Oklahoma for research services under the Integrative Activities program (CFDA 47.083). The award will support the development of a novel neurostimulation technology integrated with neuroimaging to enable individualized treatment for mental illness. The research aims to address issues of variable response effects and inter-subject variability that have...
This Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) provides $434,716 to the University of Oklahoma Health Sciences Center to develop a set of optical tools for capturing and interpreting high-speed recordings of neural activity across the entire zebrafish brain. The key objectives are to create fluorescent voltage sensors, optical microscopes, and signal processing algorithms that can simultaneously monitor millisecond-scale bursts of neural...
This Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) provides $583,679 to the University of California, Davis (UC Davis) to develop an innovative microscopy system for simultaneously imaging neurons, blood vessels, and other cellular structures within the brain. The project, titled "CAREER: Integrated Multiphoton-Phase Microscopy for Simultaneous and Correlative Imaging of Neurovascular Coupling Dynamics," aims to advance the...
This National Science Foundation Project Grant award of $299,126 will fund research at the University of Chicago from March 1, 2022 through February 29, 2024 to infer neuronal activity from anatomical connectivity maps in simplified neural cell cultures. The goal is to develop methods for understanding how physical wiring relates to activity in neural networks, which can later be applied to whole brain maps. Researchers will record functional activity from a 2D neural cell network, map...
This $487,362 federal Project Grant awarded by the National Science Foundation (NSF) Computer and Information Science and Engineering (CISE) program (CFDA 47.070) is funding a project to develop a unified computational framework for accurately reconstructing densely labeled neural circuits in the brain. The key objectives are to: Generate super-resolution 3D images of whole Drosophila brains with labeled connected neurons using multispectral labeling techniques. Create computer vision and...
This $312,039 Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) supports the University of California, Irvine in developing and deploying conformable, expandable neural interface devices to monitor brain activity and cognitive development in immature rodents. The goal is to identify neurophysiological signatures of emerging cognition as the animals perform naturalistic behaviors, using the soft, organic electronics to interface with the growing brain...
This National Science Foundation (NSF) Integrative Activities (CFDA 47.083) Project Grant award of $848,348 provides funding to the University of Iowa to acquire a Nikon CSU W1 SORA super-resolution spinning disc confocal microscope system. This advanced imaging system will enable long-term, high-resolution live imaging to support critical biological research across multiple disciplines, including evolution, development, cell biology, neurobiology, and genetics. The SORA microscope will serve...
This Project Grant award from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) provides $270,000 to the University of New Mexico (UNM) to develop an advanced optical microscopy system. The system will combine "MinFlux" high-speed protein tracking and "modal imaging" techniques to enable unprecedented spatiotemporal observation of protein interactions and dimerization kinetics in living cell membranes. The research aims to advance the...
The National Science Foundation awarded a $499,553 Project Grant to Grinnell College under the Integrative Activities program (CFDA 47.083) to acquire a laser scanning confocal microscope. The microscope will support research and teaching activities in biology, biochemistry, chemistry, and physics at Grinnell College from October 1, 2022 to September 30, 2025. Specifically, the microscope will be used to study synaptic plasticity, detect microtubule formation below the diffraction limit of...