The University of New Mexico was awarded a $414,071 project grant from the National Science Foundation Division of Molecular and Cellular Biosciences under the Biological Sciences federal grant program (CFDA 47.074). The grant will support collaborative research toward developing lifelike synthetic cells through engineered control of DNA replication from August 15, 2021 to July 31, 2024. The Biological Sciences program aims to promote advancement in the biological sciences and strengthen the...
The University of New Mexico will receive $651,450 in funding from the National Science Foundation under a three-year Project Grant award to conduct research on conformations and dynamics of modular redox enzymes via site-specific 2D infrared spectroscopy. The NSF Biological Sciences program (CFDA 47.074) aims to promote progress in the biological sciences and strengthen the nation's scientific enterprise through increasing scientific knowledge and understanding of major problems confronting the...
This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) Program grant in the amount of $170,000.00 awarded to the Regents of the University of Minnesota will support a collaborative research project to use non-canonical genetic alphabets to expand genetic codes in synthetic cells. The researchers will investigate the incorporation of non-canonical nucleotides into translation (Aim 1), the incorporation of non-canonical amino acids via non-canonical genetic alphabets (Aim 2), and...
This National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) project grant, awarded to the University of Texas Rio Grande Valley, aims to investigate the formation and replication of primitive cell-like structures called protocells. The $502,983 award, effective March 1, 2025 through February 29, 2028, has three main scientific goals: (1) using catalytic minerals to promote the synthesis and polymerization of organosulfur species into amphiphilic molecules, (2) studying the...
This $1,220,400 Project Grant awarded by the National Science Foundation (NSF) Division of Molecular and Cellular Biosciences supports a collaborative research project between investigators in the U.S. and U.K. to better understand the regulatory mechanisms controlling mammalian gene expression. The project, funded through NSF's Biological Sciences program (CFDA 47.074), aims to define the roles of different DNA regulatory elements and how they work together to precisely control gene expression....
This $299,779 National Science Foundation project grant under the Biological Sciences program (CFDA 47.074) funds research at Louisiana State University from August 2022 to July 2024 to design an RNA-based dual regulator for repetitive gene expression regulation. The research integrates biological experiments and computational studies to train scientists and engineers in interdisciplinary research. It also aims to cultivate a multidisciplinary perspective for problem-solving. Specifically, the...
This $1,000,000 Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) program supports research by the University of California, San Francisco (UCSF) to design, build, and test synthetic signaling systems built from computationally-designed de novo protein components. The goal is to develop stable, tunable, and modular signaling systems capable of precisely controlling biological processes, with applications in biotechnology such as engineered cells for...
This $300,000 Project Grant award from the National Science Foundation's (NSF) Integrative Activities program (CFDA 47.083) supports the development and experimental validation of computational tools for designing DNA nanostructures and molecular systems. The primary goal is to create novel multiscale modeling frameworks that can harness the predictive power of low-level molecular dynamics models while providing the ease of simulation offered by higher-level models. The project will also further...
The National Science Foundation Division of Molecular and Cellular Biosciences awarded Rice University a $373,174 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to conduct research toward developing lifelike synthetic cells through engineered control of DNA replication from August 15, 2021 to July 31, 2024. The Biological Sciences program aims to advance biological knowledge and understanding of major problems to strengthen the nation's scientific enterprise....
The University of Utah will receive $492,516 from the National Science Foundation Division of Molecular and Cellular Biosciences under a three-year Project Grant award titled "Role of Electric Fields and a Dynamic Local Environment in Protein-RNA Molecular Recognition." The grant funds basic research from August 1, 2021 to July 31, 2024 to advance understanding of major problems in the biological sciences by investigating the role of electric fields and the local molecular...