Project Grant 20246701542404
- The U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) awarded a $648,154 Project Grant under the Agriculture and Food Research Initiative (AFRI) competitive grants program to the Agricultural Research Service (ARS), a component of the Government of the United States. The grant supports the development of a multi-strain electron beam (e-beam)-killed vaccine to control Clostridium perfringens-induced necrotic enteritis (NE) and Mycoplasma gallisepticum-induced...
- The U.S. Department of Agriculture (USDA) awarded a $650,000 Project Grant under the Agriculture and Food Research Initiative (CFDA 10.310) to Oklahoma State University (OSU) to conduct research on developing an antibiotic-free approach to combat necrotic enteritis (NE) in poultry. Specifically, the project will screen additional commensal bacteria for their ability to inhibit the growth of Clostridium perfringens, the bacterium that causes NE, and induce host defense peptide synthesis to...
- This USDA National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) Project Grant in the amount of $180,000 awarded to Oklahoma State University (OSU) aims to identify antimicrobial metabolites and immune-boosting mechanisms produced by a commensal bacterium that can mitigate Clostridium perfringens-induced necrotic enteritis in poultry. The project has two primary objectives: 1) to identify major antibacterial and host defense peptide-inducing metabolites...
- Oklahoma State University will receive $300,000 from the National Institute of Food and Agriculture under the Agriculture and Food Research Initiative competitive federal grants program to study methods for mitigating necrotic enteritis in poultry. Specifically, the university will compare the gut microbiota of necrotic enteritis-resistant and susceptible chicken breeds when subjected to the disease. Fecal microbiota from resistant and susceptible chickens will be transplanted into naive...
- This federal Project Grant award of $650,000 from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA), under the Agriculture and Food Research Initiative (CFDA 10.310) program, aims to further optimize and evaluate self-destructing attenuated adjuvant Salmonella (SDAAS) strains for in ovo administration to chicken embryos. The goal is to enhance protective immunity against Salmonella, Campylobacter jejuni, Clostridium perfringens, and avian pathogenic E. coli...
- This $650,000 Project Grant was awarded by the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310). The grant aims to develop evidence-based, multi-stage recommendations for improving sustainability of small broiler enterprises, focusing on microbial safety, product quality, and cost-effectiveness. Key objectives include: (1) applying probiotics to reduce Salmonella contamination in...
- This $300,000 Project Grant was awarded by the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310). The objective is to develop and implement effective mitigation strategies at the production level to limit Salmonella colonization in chickens and reduce the transmission of Salmonella to poultry products and humans. The grant will fund research to evaluate the efficacy of combining...
- The Department of Agriculture's National Institute of Food and Agriculture awarded $530,000 under the Agriculture and Food Research Initiative competitive grants program to develop a trivalent vaccine that protects against Marek's disease, Newcastle disease, and infectious laryngotracheitis in poultry. With a completion date of April 30, 2026, this Project Grant will fund research at the Agricultural Research Service's Southeast Area location in Stoneville, MS to design a single vaccine using...
- This Project Grant award of $299,985.00, provided by the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310), supports research to identify viral proteins that induce cell-mediated protection against avian influenza in chickens. The goal is to develop broadly protective avian influenza vaccines for poultry. The project will be conducted by the University of Maryland, College Park over a...
- This $800,000 Project Grant awarded by the USDA National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (CFDA 10.310) will support Cornell University's development of novel vaccine delivery platforms and serological assays to address the critical challenge of highly pathogenic avian influenza (HPAI) in poultry. Specifically, the university will leverage a condorpox virus vector and self-amplifying RNA technology to rapidly develop and deploy HPAI...
The U.S. Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA) awarded a $650,000 Project Grant under the Agriculture and Food Research Initiative (CFDA 10.310) to the Division of Agriculture of the University of Arkansas. The award period is from July 1, 2024 to June 30, 2028. The project aims to develop effective interventions to mitigate necrotic enteritis (NE), a prevalent poultry disease causing estimated $6 billion in annual losses worldwide. Key objectives include: 1) developing multiepitope fusion antigen (MEFA) vaccines against Clostridium perfringens virulence factors to reduce NE in chickens, and 2) evaluating microbe-metabolized bile acid regimens to inhibit C. perfringens growth and virulence and thereby prevent NE. The proposed research leverages the Division's expertise in proteomics, immunoinformatics, and ELISA assays to advance these mechanism-based interventions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $650.0k | 5/16/24 |