The Department of Agriculture's National Institute of Food and Agriculture awarded $530,000 under the Agriculture and Food Research Initiative competitive grants program to develop a trivalent vaccine that protects against Marek's disease, Newcastle disease, and infectious laryngotracheitis in poultry. With a completion date of April 30, 2026, this Project Grant will fund research at the Agricultural Research Service's Southeast Area location in Stoneville, MS to design a single vaccine using Newcastle disease virus as a vector to insert genes encoding antigens of Marek's disease virus and infectious laryngotracheitis virus. Recombinant NDVs expressing antigens of these viruses will be tested for safety, genetic stability, and protective efficacy in chicken challenge models. If successful, a trivalent vaccine capable of protecting against all three diseases will be formulated. This vaccine aims to provide producers benefits over current attenuated live vaccines by being non-recombinogenic, genetically stable at temperatures greater than -80°C, and amenable to in ovo robotic delivery at hatcheries.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $530.0k | 4/4/23 |