This $650,000 Project Grant awarded by the U.S. Department of Agriculture's National Institute of Food and Agriculture (USDA NIFA) under the Biotechnology Risk Assessment Research Grants Program (CFDA 10.219) will fund research at Clemson University to investigate the unintended effects of commonly used site-specific recombinase genes (Cre, Flp, PhiC31) when expressed in creeping bentgrass and Arabidopsis plants. The primary objectives are to examine whether and how the recombinases may cause unexpected phenotypic changes, modifications to host gene expression, and epigenetic alterations in these plant species. This research aims to evaluate the feasibility of using site-specific recombination systems for transgene excision to enhance crop performance and biosafety, as well as provide information to regulatory agencies on assessing the risks of such biotechnology strategies. The project will be conducted over a period of 4 years, from September 1, 2024 to August 31, 2028.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $650.0k | 8/8/24 |