This $627,000 Project Grant from the US Department of Agriculture National Institute of Food and Agriculture's Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310) will fund research at the University of Illinois from May 1, 2023 to April 30, 2026. The research aims to identify early gene and protein expression changes after equine joint injuries to further understanding of post-traumatic osteoarthritis (PTOA) development. Twelve horses will undergo controlled fetlock chip injuries to one joint, with the other serving as an uninjured control. Joint samples will be collected at surgery, every eight weeks, and at follow-up surgeries to analyze gene and protein expression changes over time. Results may indicate predictive biomarkers and inform future early diagnostic and treatment approaches. A $100,000 sub-award to the University of Minnesota will support related molecular marker research. Outcomes include new insights into PTOA pathogenesis to enable early intervention and improve equine welfare.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $627.0k | 4/4/23 |
Grant Number | Description | Subgrantee | Prime Award | Dollars Obligated (Click to sort descending) | Updated At (Click to sort ascending) |
|---|---|---|---|---|---|
19627S | Regents Of The University Of Minnesota | Project Grant 20236701539656 | $34.1k | 3/28/24 |