The University of Florida was awarded a $362,689 Project Grant by the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279). The award titled "University of Florida Partnerships Across Interdisciplinary Networks: Training through Engineering, Epidemiology & Addiction Medicine (UF PAIN TEAM)" will establish an interdisciplinary postdoctoral training program to develop the next generation of independent...
This federal Project Grant award in the amount of $351,097 was provided by the National Institute of Neurological Disorders and Stroke (NINDS), which is part of the National Institutes of Health (NIH). The grant was awarded under the NIH's Drug Use and Addiction Research Programs (CFDA 93.279) to establish a rigorous and supportive interdisciplinary training program in clinical pain research at Mass General Brigham (MGB) in Boston. The program will support a diverse pool of 8 postdoctoral...
This $366,000 federal Project Grant award, titled "VALIDATION OF A NONOPIOID ANALGESIC PATHWAY IN HUMAN SENSORY GANGLIA AND SPINAL CORD," was issued on September 15, 2024 by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program. The award was granted to the University of Florida to conduct advanced biomedical research focused on transforming healthcare for military service members and the broader public. The research will explore innovative...
This federal Project Grant award, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279), is focused on developing novel methods for selectively stimulating nociceptors (pain receptors) and measuring the brain's nociceptive-specific response in both healthy individuals and those with the chronic pain condition fibromyalgia. The $2,314,276 award to Emory University will fund the creation of a new...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (CFDA 93.279 - Drug Use and Addiction Research Programs) provides $3,320,159 to North Carolina State University to develop and validate a comprehensive battery of tests to assess emotional and cognitive function in dogs with naturally occurring osteoarthritis pain. The goal is to establish a clinically-relevant animal model for evaluating the biopsychosocial impacts of chronic musculoskeletal...
This $242,061 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279) establishes an interdisciplinary clinical pain research training program at Mass General Brigham (MGB) in Boston. The program will support 8-12 postdoctoral fellows over 5 years, providing protected research time and dedicated training to expand the pool of early-career investigators capable of launching successful clinical...
This Project Grant award of $838,750 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Use and Addiction Research Programs (CFDA 93.279), supports research by the University of Florida to investigate the role of GTP cyclohydrolase 1 (GCH1) in chronic orofacial neuropathic pain. The project aims to determine if orofacial neuropathic pain increases GCH1 expression in the trigeminal ganglia and central pain- and reward-related pathways, and whether...
This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), provides $387,000.00 to Florida Atlantic University to develop novel intranasal delivery cyclic peptide analgesics for pain management. The research aims to create new peptide-based pain medications that combine kappa-opioid receptor agonist activity with serotonin and/or norepinephrine delivery, with the goal of improving pain relief while minimizing...
The University of Utah received a $698,670 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279) to implement the University of Utah Program to Provide Pain Research Knowledge (UP3RK). The UP3RK program aims to train an interdisciplinary group of post-graduate scholars in clinical pain research, with a focus on non-pharmacological pain treatments, interventions for pain and co-morbidities,...
This $2,569,851 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Drug Abuse and Addiction Research Programs (CFDA 93.279), supports research to investigate how the PD-L1/PD-1 immune checkpoint pathway controls physiological and pathological pain, as well as opioid analgesia, through neuronal, immune, and glial mechanisms. The project aims to validate the actions of PD-L1 and the checkpoint inhibitor nivolumab on neuroinflammation and...
This federal Project Grant award in the amount of $3,196,061 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279). The award will fund research at the University of Florida to rigorously test the reliability and validity of pain-related behavioral metrics in horses. Specifically, the research will assess quantitative sensory tests, locomotion, and activity/spontaneous behavior in equine osteoarthritis populations. The goal is to close gaps between pain assessments in horses and humans, providing well-validated measures to facilitate the development of non-opioid pain therapies. The project will be conducted over a 3-year period from September 2024 to August 2027.