Project Grant 1853207

The National Center for Advancing Translational Sciences (NCATS), under the CFDA 93.350 Federal Grant Program, awarded a $230,499 Project Grant to Vindhya Data Science Inc. on July 15, 2024. The grant supports the development of BIOCLIN, a precision medicine software platform designed to enable RNA sequencing-based biomarker clinical trials. The key products and services to be delivered under this grant include: Conducting user research to understand the needs of investigators for running RNA...

This federal Project Grant award from the National Cancer Institute (NCI), under the Cancer Detection and Diagnosis Research program (CFDA 93.394), provides $388,673 to develop novel statistical methods to identify and evaluate predictive biomarkers using progression-free survival (PFS) data from non-randomized Phase II cancer clinical trials. The project aims to address key challenges in this area, including the limited sample sizes of Phase II trials, high-dimensional biomarker data,...

This $255,706 National Science Foundation SBIR Phase I Project Grant to Metfora LLC supports the development of a novel multiplexed metabolite diagnostic blood test for early detection of chronic diseases. The NSF Technology, Innovation, and Partnerships program aims to advance science and engineering solutions to national challenges through innovation and partnerships. Specifically, Metfora will use mass spectrometry and artificial intelligence to analyze specific panels of circulating...

This federal Project Grant award from the National Science Foundation (NSF) Computer and Information Science and Engineering (CISE) program (CFDA 47.070) provides $450,205 to Oregon Health & Science University (OHSU) to develop novel computational methods for analyzing high-dimensional biomedical data with inherent heterogeneity. The key objectives are to: 1) detect biologically/clinically meaningful patient subgroups by leveraging multi-omics data through novel supervised clustering...

This National Science Foundation project grant of $260,000 supports research at the University of North Carolina at Chapel Hill to develop statistical analysis frameworks for precision medicine incorporating abundant data features. Funded under the Mathematical and Physical Sciences program (CFDA 47.049), the three-year award running from August 2022 to July 2025 will adapt semi-parametric and reinforcement learning methods to precision medicine scenarios involving medical images, genetic...

The U.S. National Science Foundation awarded a $275,000 SBIR Phase I Project Grant to Om Therapeutics Inc. in La Jolla, CA under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program. The project aims to enable the discovery of new medicines at an unprecedented rate by empowering researchers to conduct drug discovery programs through the generation of massive, empirical, and scalable data on small molecule and protein interactions using machine learning. The key innovation is...

The federal Project Grant award from the National Cancer Institute (NCI) provides $159,803 over a period of 5 years (9/3/2024 - 8/31/2029) to support the "INTEGRATIVE MULTIOMICS AND CLINICAL LABORATORY TRANSLATION FOR ADVANCED, RARE, AND PEDIATRIC CANCERS" project. The award aims to incorporate emerging genomic, transcriptomic, epigenomic and proteomic technologies to analyze advanced, rare, and pediatric cancers, and translate the results into clinically actionable information through...

This federal Project Grant award from the National Cancer Institute (NCI), under the Cancer Detection and Diagnosis Research program (CFDA 93.394), provides $419,133 to Massachusetts Institute of Technology (MIT) to develop the "AscitesPredict" technology. This zero-passage "ex vivo tumor biosensor" uses single-cell analysis and machine learning to evaluate cell identities and therapeutic sensitivities in patient ascites samples, which are often discarded in standard clinical...

This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $700,000 to Prenosis, Inc., a small disadvantaged business based in Chicago, Illinois, to validate the company's Immunix platform for precision medicine patient stratification in acute care settings. The Immunix platform combines clinical data, novel biomarker assays, and artificial intelligence-enabled tools to classify...

This National Science Foundation Project Grant of $606,649 will support the development of an engineered cyber-physical system combining advanced biological models and artificial intelligence methods to enable precision medicine for cancer treatment. Awarded under the Computer and Information Science and Engineering program, the funding will be used by Brigham and Women's Hospital and its parent organization Partners Healthcare System from October 2022 to September 2025. Specifically, the...