Project Grant 1843954

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) grant, awarded to Tissueform, Inc., a for-profit woman-owned small business in Boulder, Colorado, aims to develop a library of human-based bioinks for 3D bioprinting applications. The $274,822 award, with a performance period from September 2024 to August 2025, will focus on creating granulated bioinks for tissues such as cartilage, bone, skin, liver,...

This SBIR Phase I project, awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), aims to develop a novel liquid crystal polymer (LCP) called Tullomer to address limitations in fused deposition modeling (FDM) 3D printing. The $275,000 grant, awarded to Z-Polymers, Inc., will fund the optimization of Tullomer's monomer ratios, integration of nucleation additives, and control of mesogenic state formation to enhance...

This $500,000 Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences, under the Biological Sciences federal grant program (CFDA 47.074), will support research to develop an end-to-end continuous manufacturing process for cell therapies using robotics and microfluidic technologies. The Georgia Tech Research Corporation will receive funding to create a more integrated workflow based on microfluidic device-enabled genetic engineering, cell expansion, and...

This federal Project Grant award of $460,500 from the National Institute of Biomedical Imaging and Bioengineering (NIBIB) under the Discovery and Applied Research for Technological Innovations to Improve Human Health program (CFDA 93.286) is aimed at developing novel bioprinting methodologies for the production of human stem cell-based organoids. The key objectives are to: 1) Create a customized bioink formulation using proteins, polysaccharides, and functionalized nanoparticles to foster the...

This $305,548 National Science Foundation Engineering grant will support the acquisition of a multi-modal, high-resolution 4D bioprinting platform at North Carolina State University. The platform features laser induced forward transfer, micro-valve drop-on-demand, and micro-extrusion printing capabilities for fundamental research and workforce training in additive manufacturing, tissue engineering, plant and animal cell biology, functional materials engineering, and bioelectronics. With...

This National Science Foundation (NSF) Engineering program (CFDA 47.041) Project Grant award of $600,000 to the University of California, San Diego (UCSD) aims to develop additive and subtractive manufacturing processes to rapidly print and erase biomaterials capable of high-density wireless mechanical sensing. Specifically, the project will engineer photolabile ferroelectric bioinks incorporating piezoelectric nanoparticles with electrochromic dyes within a hydrogel. These bioinks will be...

This SBIR Phase I project, awarded by the National Science Foundation (NSF) under the NSF Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084), aims to develop a method to turn on cancer immunotherapies only at the site of disease. The $275,000 award will support Synsorybio, Inc., a for-profit organization, in creating protein switches that activate immunotherapies in response to disease signals, rather than indiscriminately throughout the body. This approach seeks to improve the...

This $275,000 Small Business Innovation Research (SBIR) Phase I award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program supports the development of a label-free, high-resolution, high-throughput protein screening platform called Vibrational Spectroscopy with Metasurface Optics (VISMO). The technology aims to enable simultaneous, minute-scale measurement of millions of protein samples, which would dramatically improve the lengthy and costly cycles...

The National Science Foundation awarded a $275,000 Project Grant to Oraliva, Inc. under the Technology, Innovation, and Partnerships program to develop a portable, programmable single cell cytology platform for the early detection of epithelial cancers. The platform will combine microfluidics and artificial intelligence to classify potentially cancerous tissue in near real-time through multiparameter single-cell analysis and automated evaluation. The objectives are to link different clinical...

This National Science Foundation Project Grant of $319,476 will fund research at the University of Virginia from March 2023 through February 2026 under the Engineering program (CFDA 47.041). The research aims to establish the foundational science for voxelated bioprinting through elucidating the nonlinear fluid dynamics of all-aqueous printing of viscoelastic droplets in yield-stress fluids. A printing platform will be developed to study droplet printing dynamics in real time. Control strategies...