Project Grant 2404668

Award Date 7/15/24
Completion Date 2/28/25
Dollars Obligated $275K
Federal Grant Program
47.084
Assistance Type
Project Grant
Place of Performance
Cambridge, MA 02139, USA

The National Science Foundation (NSF) awarded a $275,000 SBIR Phase I grant to Synsorybio, Inc. under the NSF Technology, Innovation, and Partnerships (CFDA 47.084) program. The goal of this project is to develop a method to activate cancer immunotherapies only at the site of disease, in order to create safer and more effective cancer treatments. The project aims to engineer protein-based therapeutics that can "sense and respond" to disease signals, turning on the immunotherapy only where it is needed and avoiding off-target effects in healthy tissues. This proof-of-concept project may lay the groundwork for a versatile platform technology to conditionally control the activity of protein-based drugs, with potential applications across various therapeutic areas. The award period runs from July 2024 to February 2025.

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