Formula Grant 1901VAOANS

The National Institute of Neurological Disorders and Stroke (NINDS) has awarded a $862,420 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to Quiver Bioscience Inc., a for-profit biotechnology company. The objective of this 3-year project is to establish an integrated platform that combines machine learning-based antisense oligonucleotide (ASO) design tools and in vitro neuronal functional assays using Quiver's optical...

The National Institute on Deafness and Other Communication Disorders (NIDCD), under the Research Related to Deafness and Communication Disorders Federal Grant Program (CFDA 93.173), awarded a $670,525 Project Grant (R01DC022051) to The Ohio State University. The grant, effective May 1, 2025 through April 30, 2030, aims to develop objective clinical tools for managing children with Auditory Neuropathy Spectrum Disorder (ANSD). Key objectives include: 1) establishing electrocochleography as a...

The National Eye Institute (NEI) awarded a $882,971 Project Grant (CFDA 93.867 - Vision Research) to Opus Genetics Inc. for the development of OPGX-RHO, a single-vector AAV gene therapy for the treatment of autosomal-dominant retinitis pigmentosa (ADRP). The project aims to complete chemistry, manufacturing, and controls of a clinical-grade batch of OPGX-RHO, including device compatibility and stability studies, as well as conduct efficacy and safety/toxicology studies in a large animal model...

The National Eye Institute (NEI) awarded a $623,090 Project Grant (CFDA 93.867 - Vision Research) to Oregon Health & Science University (OHSU) to develop an advanced visible-light optical coherence tomography (VIS-OCT) system and analytical methods for evaluating the oxygen-induced retinopathy (OIR) animal model. The goal is to build a wide-field VIS-OCT device capable of quantifying retinal blood flow, oxygen saturation, and vascular changes associated with OIR, which models retinopathy...

This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), aims to develop an accurate and continuous monitoring platform for classifying apnea of prematurity (AOP) in premature newborns. The $371,021 award to Makani Science Inc. will fund a two-phase effort to create a multimodal monitoring system with sensors optimized for detecting AOP, along with advanced machine learning models to classify...

This Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310) provides $508,816 to The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. to investigate the effects of organophosphate (OP) exposure on white matter microstructure and brain connectivity. The research aims to use high-resolution diffusion tensor imaging (DTI) and functional MRI to analyze the pathologic white matter...

This Cooperative Agreement award under the Trans-NIH Research Support program (CFDA 93.310) from the National Institutes of Health (NIH) provides $552,787 in funding to Old Dominion University (ODU) to develop YK-4-250, a novel radiation mitigator for gastrointestinal acute radiation syndrome (GI-ARS). The research aims to investigate the mechanisms by which YK-4-250 can mitigate GI-ARS through modulating the renin-angiotensin system and reactive oxygen species signaling. Key objectives...

The Office of Naval Research (ONR) awarded a Project Grant under the Basic and Applied Scientific Research program (CFDA 12.300) to Robert Morris University in the amount of $125,000.00. The grant, awarded on March 11, 2025, will support computational modeling research on blast-induced traumatic brain injury in an animal model. The project aims to develop advanced computational models and digital twin technologies to predict injury risks for military personnel. This award is part of ONR's...

This Cooperative Agreement award from the National Aeronautics and Space Administration (NASA) under the Office of STEM Engagement (OSTEM) program (CFDA 43.008) provides $100,000.00 for the development of a compact, non-invasive, and efficient vision screening system for long-term spaceflight missions. The research aims to evaluate a novel framework enabled by artificial intelligence (AI) and virtual reality (VR) as a proof-of-concept, robust, low-cost system for detecting visual deficits caused...

This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a methodology for simultaneous analysis of adenosine-to-inosine (A-to-I) RNA editing sites in targeted RNAs and specific neuronal cell subtypes. The $420,744 award to Oregon Health & Science University will support this research, which seeks to better...