This three-year Project Grant from the National Science Foundation's Division of Integrative Organismal Systems, totaling $550,000, will fund research examining corticocortical communication in the brain under different network states. The Trustees of the University of Pennsylvania, operating as the Clinical Practices of the University of Pennsylvania, will investigate how visual responses are transmitted between local networks in layers 2-3 of primary visual cortex when the brain is in gamma...
This $266,538 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports collaborative research on the effects of connectivity architecture and distributed delays in brain network dynamics. The project aims to establish a quantitative framework that considers both spatial connectivity and temporal history of neural interactions, using networks of coupled equations with time delays. The research team, led by The Research...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $816,063 to The Trustees of Columbia University in the City of New York to conduct research on the neural mechanisms underlying how social stimuli elicit motivated behavior. The key focus of the research is to understand how neural representations of social rank information, such as dominant and submissive social cues, converge onto brain...
This three-year Project Grant from the National Institutes of Health's National Institute of Mental Health will fund $2,668,158 to integrate structural and functional datasets to understand how neural structure enables function in the mouse visual cortex. The Regents of the University of California, San Francisco will analyze the largest calcium imaging dataset collected to date from an entire column in mouse primary visual cortex, comprising volumetric 2-photon and 3-photon imaging recordings...
This Project Grant award from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program, totaling $722,109, supports a collaborative research project between computational and experimental neuroscientists at Brown University. The project aims to investigate the role of brain waves in the prefrontal cortex during decision-making and categorization tasks, with the goal of uncovering the mechanisms and meaning of brain rhythm frequency shifts. The...
This $1.8 million project grant from the National Institutes of Health's National Institute of Mental Health will fund the development of high-throughput methods for measuring synaptic connectivity at single-cell resolution in the cerebral cortex. Over a three-year period from September 2022 through August 2025, The Broad Institute, Inc. will pursue viral, functional, and molecular approaches to map local cortical circuitry. These include optimizing rabies-based trans-synaptic tracing for...
This $1,999,635 project grant from the National Institutes of Health's National Institute of Neurological Disorders and Stroke (NIH NINDS) will fund research into understanding feedforward and feedback signaling between neuronal populations. The grant was awarded to Albert Einstein College of Medicine on March 15, 2022 for a period ending February 28, 2025. The project aims to advance understanding of how feedforward and feedback signaling work together in the visual system by analyzing...
The National Science Foundation (NSF) Directorate for Engineering (CFDA 47.041) awarded a $300,000 Project Grant to the University of California, San Diego (UCSD) for a collaborative research effort titled "Analysis and Control of Nonlinear Oscillatory Networks for the Design of Novel Cortical Stimulation Strategies." This 3-year project aims to develop new theories and tools to predict the onset and spreading of epileptic seizures, and to inform the use of novel electrical brain...
This $600,000 Project Grant award from the National Science Foundation (NSF) Computer and Information Science and Engineering (CISE) program supports research at Carnegie Mellon University to develop methods for uncovering the hidden interconnections among the components of complex networked dynamical systems. The project aims to infer the connectivity structure of systems like brain networks, power grids, and pandemic spread models where only a subset of the nodes or agents can be directly...
This Project Grant award of $314,283 from the National Science Foundation's (NSF) Computer and Information Science and Engineering (CISE) program aims to develop a unified framework for analyzing general graph dynamics and interconnected networks. The primary objectives are to: 1) derive a generalized, interpretable framework for graph dynamics using advanced methods like sparse symbolic dynamics and probabilistic modeling; 2) investigate how dynamics in one network, such as disease-spreading or...