Artificial intelligence and dashboard tools to collect, anonymize, and summarize companion animal antimicrobial use data - the objective of the proposed project is to develop a data extraction,…

The Food and Drug Administration awarded Cornell University $400,000 under Cooperative Agreement U01FD008648 on September 20, 2025, to develop artificial intelligence and dashboard tools for companion animal antimicrobial use surveillance. Funding flows through the Food and Drug Administration Research program (CFDA 93.103).

The project creates a large-language-model pipeline and R Shiny dashboard to extract, anonymize, and analyze antimicrobial use data from veterinary electronic health records. The LLM will operate across multiple EHR systems and process de-identified record-level data including antimicrobial drugs, dosage, duration, patient weight, indication for use, and animal visit counts. Participating veterinary practices will process their own EHR data on a secure platform and share only anonymized results. The AMU Data Visualizer dashboard will standardize analysis and reporting to reduce the time lag between data collection and publication that has characterized prior surveillance efforts.

Place of performance is New York. The award period runs through August 31, 2030.

Artificial intelligence and dashboard tools to collect, anonymize, and summarize companion animal antimicrobial use data - the objective of the proposed project is to develop a data extraction, analysis, and reporting pipeline for sustainable companion animal antimicrobial use (AMU) surveillance. Previous surveillance efforts have been restricted to snapshots of AMU in specific veterinary practices or at limited timepoints because AMU data is time- consuming and difficult to collect. In addition, there have been substantial time lags between AMU data collection and publication because each companion animal AMU surveillance study has conducted a bespoke analysis of AMU data that requires a high-level of statistical, data visualization, and software skills. Recent advances in natural language processing (NLP) and machine learning, particularly large-language models (llms), have made efficient AMU data collection possible. However, even with new models, challenges remain to create a scalable system for long-term data collection. The proposed project will overcome these challenges by creating an LLM to extract AMU data that is agnostic to the veterinary electronic health record (EHR) system used and create a dashboard to streamline AMU analysis. The first aim is to make an LLM that is scalable and generalizable across ehrs by developing IT on free text from multiple ehrs and validating IT against existing gold-standard AMU datasets collected from manual EHR review. The LLM will be available to participating practices on a secure platform to ensure data privacy and security. Practices can process their own EHR data and share only DE-identified record-level AMU data, including antimicrobial drug(s) used, dosage, duration, patient weight, and indication for AMU, plus the number of animal visits. The second aim creates an rshiny dashboard, the AMU data visualizer, to streamline AMU data analysis and generate standardized AMU reports. The dashboard will take the anonymous information generated by the LLM, or by other AMU data extraction methods, and generate AMU metrics, such as prevalence and number of defined daily doses, with customizable filters to understand AMU across all companion animal sectors (e.g., primary care VS. Emergency care, young animals VS. Geriatric animals). The AMU data visualizer will allow anyone, regardless of their statistical software skills, to create AMU reports, aggregated tables, and figures for their practice. The third aim is to collect anonymous, aggregated AMU reports from participating veterinary practices to identify national trends in companion animal AMU. Aggregated AMU tables from the AMU data visualizer will be combined into annual, public AMU reports with benchmarks for different practice types and trend analyses. The proposed project is conceptually innovative because IT develops an EHR-agnostic AMU data collection method and a reproducible analysis pipeline, and does not require practices to share EHR free text that could contain sensitive or identifiable information. The project is technically innovative because IT advances LLM data extraction by having the LLM "show its work" for easy data verification. Overall, the LLM, AMU data visualizer, and aggregated reports will reveal the full picture of companion animal AMU.