Cooperative Agreement R43FD005669

This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research) provides $312,088 to Sojourn Medtech LLC to develop the CANSIM simulator. The CANSIM is a smart, personalized, and dialysis-specific training device to teach critical cannulation skills to dialysis nurses and patient care technicians. The key features include: 1) dialysis-specific design, 2) realistic and low-maintenance...

This $550,000 Project Grant awarded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program supports the development of a remote monitoring system to reduce infections among patients undergoing peritoneal dialysis (PD). The project aims to enable real-time, continuous, and quantitative monitoring of biomarkers in dialysate to facilitate early detection and diagnosis of PD-associated infections. To achieve this, the project team will:...

This $445,870 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) aims to develop a mature and functional human kidney organoid model. The key product is a spatially patterned, mature, and functional human kidney organoid that can accurately recapitulate normal kidney organogenesis and physiology. This will be achieved by optimizing the assembly and culture conditions of...

This $305,000 project grant awarded by the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the development of a clinical decision support system (CDSS) called Sepsis FLO. The CDSS is designed to precisely guide blood volume diagnosis and treatment for sepsis patients. Key activities include: 1) Developing an alpha prototype of the CDSS through user-centered design; 2) Validating three functional...

This federal Project Grant award of $350,000.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award to Katharos, Inc. (UEI: XSTCCEP41DN1) supports the development of a novel extracorporeal technology called the "Phosfilter" device. The goal is to enhance the removal of excess phosphate from the blood of patients with kidney disease on...

This Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), will fund the development of genetically encoded chloride sensors to measure sodium-chloride transport in the kidneys of live mice. The $400,820 award will enable researchers at Wayne State University to generate transgenic mouse models expressing chloride-sensing probes. This will allow them to...

The National Science Foundation (NSF) has awarded a $1,000,000 Cooperative Agreement under the NSF Technology, Innovation, and Partnerships program (CFDA 47.084) to Aidar Health, Inc.'s Rapid Advantage Division. The purpose of this 2-year award is to develop a comprehensive remote health management system for patients with chronic kidney disease. Key deliverables include a medical device, digital tools with advanced analytics capabilities, and a novel patient engagement feature using...

This $199,130 Project Grant was awarded on July 15, 2025 by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), to The General Hospital Corporation (Massachusetts General Hospital) to examine the clinical utility of patient-reported outcome measures (PROMs) in the care of individuals with advanced chronic kidney disease (CKD). The project aims to: 1) Develop and validate risk...

This $464,750 federal Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (CFDA 93.847 - Diabetes, Digestive, and Kidney Diseases Extramural Research) aims to revolutionize renal histopathology by integrating multiplexed immunofluorescence and machine learning/AI-based image analysis. The goal is to develop an advanced imaging and analysis platform that can generate quantitative, multi-marker biomarkers to enhance diagnostic precision and patient...

This Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The $737,949 award, granted on September 24, 2025, supports research conducted by the University of California, San Francisco to explore the potential of using bioelectrical impedance spectroscopy (BIS) to improve the assessment of fluid excess during hemodialysis treatment and guide...