Cooperative Agreement R41TR001196

This $500,000 Project Grant from the National Science Foundation's Technology, Innovation, and Partnerships program aims to develop a novel human stem cell-based microfluidic developmental toxicology platform. The University of Michigan will receive funding from September 2022 to August 2024 to conduct technological development of a repeatable, controllable, high-throughput microfluidic system for generating three-dimensional multicellular organoid models for toxicity testing. The platform seeks...

This Project Grant award from the National Institutes of Health (NIH) Research Infrastructure Programs (CFDA 93.351) provides $270,428 to TEO Therapeutics Incorporated, a small disadvantaged business, to develop a biomimetic platform for more efficient pharmaceutical drug development in oncology. The key products and services to be delivered include: Refining and testing a proof-of-concept hardware product line for a Shell-Free Quail Xenograft Assay, optimizing throughput and assessing...

Ortuvo LLC received a $256,000 Project Grant award from the National Science Foundation on June 1, 2021 to develop a fully screen printed electric cell-substrate impedance sensing toxicity assay. The award is part of the NSF's Technology, Innovation, and Partnerships program (CFDA 47.084), which seeks to advance science, engineering, and innovation leading to breakthrough technologies and solutions to national challenges. Under the one-year project period ending November 30, 2022, Ortuvo will...

Khloris Biosciences, Inc. received a $3.46 million Project Grant from the National Institutes of Health National Heart, Lung and Blood Institute to develop and validate a collection of induced pluripotent stem cell-derived cardiomyocyte cell lines. Under the Cardiovascular Diseases Research program (CFDA 93.837), Khloris will establish 50 cell lines from healthy individuals and patients with common hereditary cardiac disorders such as hypertrophic cardiomyopathy, dilated cardiomyopathy, and long...

This $500,000 Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences, under the Biological Sciences federal grant program (CFDA 47.074), will support research to develop an end-to-end continuous manufacturing process for cell therapies using robotics and microfluidic technologies. The Georgia Tech Research Corporation will receive funding to create a more integrated workflow based on microfluidic device-enabled genetic engineering, cell expansion, and...

The National Institute of Environmental Health Sciences (NIEHS) awarded Xcellassay, Inc. a $306,872 Project Grant under the Environmental Health (CFDA 93.113) federal grant program. The grant funding will support the development and characterization of a hand-held, bioassay-based test strip for rapid, in-field detection of water contamination by endocrine-disrupting chemicals (EDCs). The goal is to create a 1 x 1.5 cm detection strip printed with 20 nuclear receptor sensors that can be...

Oregon Health & Science University (OHSU) received a $390,000 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded May 1, 2026, with completion targeted for March 31, 2031. The research focuses on developing multi-scale and multi-modal computational modeling approaches to predict drug response effects on patient cell samples at single-cell resolution. The project will create novel...

Partillion Bioscience Corp. was awarded a $659,037 Project Grant from the National Institutes of Health's National Institute of General Medical Sciences to develop reagent products enabling high-throughput screening and selection of single cells based on secreted bio-products. Under the Biomedical Research and Research Training program (CFDA 93.859), Partillion plans to transition its lab-on-a-particle technology—highlighted as a 2020 SLAS Innovation Award winner—into the first reagent product...

Attogene Corporation received a $257,312 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113) to develop a novel electrochemical biosensor for detecting organophosphate and carbamate (OPAC) pesticides. The award, obligated on August 26, 2025, with a completion date of June 30, 2026, funds the creation of a portable, user-friendly, low-cost detection technology designed to address significant limitations in...

Federal Project Grant Award Summary The University of Hawaii at Manoa received a $156,500 Project Grant award from the National Institute of Environmental Health Sciences (NIEHS) under the Environmental Health program (CFDA 93.113), effective April 9, 2026, through April 8, 2028. This award supports the development and validation of New Approach Methodologies (NAMs) for developmental and reproductive toxicity (DART) assessment using pluripotent stem cell-derived morphogenesis models. The...