Cooperative Agreement HU00011920119

The Defense Health Agency awarded a $1,131,357 Project Grant titled "MicroRNA Biomarkers of Cumulative Blast-Mild Traumatic Brain Injury (Micro BCB)" under the Military Medical Research and Development (CFDA 12.420) program. The grant supports research conducted by the Seattle Institute for Biomedical and Clinical Research, a non-profit institute, to investigate the use of microRNA biomarkers for detecting and monitoring the impact of mild traumatic brain injury related to blast...

This $2,696,634 Cooperative Agreement award, granted by the Uniformed Services University of the Health Sciences under the Uniformed Services University Medical Research Projects program (CFDA 12.750), supports a research project to utilize a novel 3D human brain-like tissue model to investigate the distinct pathological mechanisms triggered by blast and blunt traumatic brain injuries. The primary research objectives are to characterize alterations in mitochondrial dysfunction, axonal structural...

The University of Pittsburgh was awarded a $1,306,281 Project Grant under the Department of the Army's Military Medical Research and Development program (CFDA 12.420) to conduct the "MITOCHONDRIAL INFLAMMATORY SYNAPTIC SYSTEMS IMAGING OF NEUROINJURY (MISSION) FOR MILD REPETITIVE TRAUMATIC BRAIN INJURY" research project. The award began on July 1, 2024 and is scheduled for completion on June 30, 2028. The project aims to study the mechanisms of mitochondrial inflammation and synaptic...

This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), part of the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $211,875.00 to New York University School of Medicine to study the long-term neuroanatomical consequences of repetitive head impacts in former American football players. The research aims to investigate structural changes in the brain, such as in the sulci, ventricles,...

This $1,251,718 Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) will fund the Heart and Lung Outcomes Post-TB (HALO POST-TB) study. The study aims to elucidate the prevalence, trajectory, and mechanisms of cardiopulmonary abnormalities after tuberculosis (TB), and examine the role of HIV coinfection as an effect modifier. The research will enroll 480 individuals with a history of pulmonary TB and 120 healthy comparators in...

This $1,526,245 Project Grant awarded on July 1, 2024 by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) will fund the "MITOCHONDRIAL INFLAMMATION SYNAPTIC SYSTEMS IMAGING OF NEUROINJURY (MISSION) FOR MILD REPETITIVE TRAUMATIC BRAIN INJURY" research project at the University of Pittsburgh. The project aims to investigate mechanisms and treatments for mild, repetitive traumatic brain injury through research on mitochondrial...

This Project Grant award from the National Center for Complementary and Integrative Health (NCCIH), under the Research and Training in Complementary and Integrative Health program (CFDA 93.213), will support research to evaluate the neurobiological effects of cranial osteopathic manipulative medicine (COMM) as a non-invasive approach to alleviate symptoms and enhance neural tissue recovery following traumatic brain injury (TBI). The $444,816 award, with a period of performance from September...

This $309,279 Project Grant award, funded by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program, supports a research study on traumatic brain injury (TBI) and psychological health conducted by Florida State University. The primary objectives are to adapt the Ohio State University TBI Identification Method and the STAIR-NT intervention for first responders with TBI, analyze the data, and disseminate the study findings. Key sub-award activities...

This $706,010 Project Grant award from the Department of the Army Medical Command's Military Medical Research and Development program (CFDA 12.420) will support research conducted by the University of Birmingham in the United Kingdom. The grant will fund a project titled "REAL-TIME ASSESSMENT OF RETINAL PERFUSION AND BLOOD FLOW AS A SURROGATE MEASURE FOR CEREBRAL PERFUSION IN SEVERE TRAUMATIC BRAIN INJURY" over a 3-year period from August 1, 2024 to July 31, 2027. The research aims...

This Project Grant award, valued at $1,322,705.00 and awarded by the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420), supports research at Craig Hospital to develop and evaluate a fatigue intervention program for adults with traumatic brain injury (TBI). The award will fund a multi-year research initiative to adapt and test the feasibility of an evidence-based fatigue management intervention for TBI patients, with the goal of improving functional...