Cooperative Agreement FA70001920035

This $801,972 National Science Foundation project grant funded quantitative molecular dynamics research on extremophile metalloproteins through 2026. The grant was awarded under the Biological Sciences program (CFDA 47.074) to the Seti Institute to study proteins from organisms thriving in extreme environments like high temperatures and pressures. The Seti Institute will lead experiments using novel synchrotron techniques like nuclear resonance vibrational spectroscopy and time domain...

This Project Grant from the National Science Foundation Division of Polar Programs, under the Polar Programs federal grant program (CFDA 47.078), provides $210,495 to support research examining how microbial extremophiles in Antarctica respond to environmental changes in salinity. Led by researchers at the University of Tennessee, the grant will fund comparative analyses of gene expression patterns and secondary metabolite production in lab microcosm studies using microbial isolates previously...

This Project Grant award from the National Science Foundation's Geosciences program (CFDA 47.050) provides $470,558 to Old Dominion University Research Foundation (Odurf) to study the use of adenosine triphosphate (ATP) as a biomass indicator for microbes in marine ecosystems. The project aims to develop an improved method for measuring particulate ATP (pATP) to provide high-resolution data on the distribution of live microbial biomass in different ocean regions and depths. The research will...

The Defense Advanced Research Projects Agency (DARPA) awarded a $4,572,797 Cooperative Agreement under the Research and Technology Development program (CFDA 12.910) to the Texas A&M Engineering Experiment Station (Tees) to support the "Assured Microbial Preservation in Harsh or Remote Areas (AMPHORA)" project. The project aims to develop transformative defense capabilities by conducting innovative, high-risk, high-reward research on microbial preservation systems that can survive...

This $1,373,044 project grant from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research at the Massachusetts Institute of Technology to develop microbial strains with minimal genomes for integrated bioprocessing using supercritical carbon dioxide. The goal is to elucidate the genotype-phenotype relationship of tolerance to supercritical CO2 for a selected microorganism and construct a reduced genome strain displaying the desired tolerance phenotype....

This Cooperative Agreement award from the Department of Commerce National Oceanic and Atmospheric Administration (NOAA) under the Ocean Exploration program (CFDA 11.011) provides $256,089.00 to Rockefeller University to advance marine environmental DNA (eDNA) technology for monitoring ocean life. The key objectives are to: 1) benchmark eDNA against traditional fish survey methods by incorporating eDNA sampling in an ongoing marine fish survey in New Jersey; and 2) develop graphic tools for...

The National Institute of General Medical Sciences (NIGMS) awarded Brandeis University a 5-year, $396,510 Project Grant under the Biomedical Research and Research Training Program (CFDA 93.859) to study archaeal cell biology and adaptation to mechanical stresses. This research aims to advance the understanding of how microbial communities, including archaea, influence human physiology by investigating how archaeal cells respond to shear, confinement, osmotic shock, and crowding. The grant will...

This Project Grant award from the National Science Foundation's (NSF) Division of Emerging Frontiers, under the Biological Sciences program (CFDA 47.074), provides $428,994 to the University of Delaware to conduct collaborative research on how deep-sea animals adapt to extreme conditions in the ocean. The research team will use the comb jelly (ctenophore) as a model organism to investigate the molecular and cellular mechanisms that allow marine organisms to survive freezing temperatures and...

This Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) provides $732,388 to Syracuse University to conduct collaborative research on the diversity and evolution of extremophilic microbial eukaryotes. The research aims to document the biodiversity of microbial eukaryotes across geothermally-active spring systems, describe new species, and improve reconstructions of the eukaryotic tree of life. The project will leverage single-cell...

This $276,000 National Science Foundation project grant supports research investigating gene regulation in the thermophile Thermus thermophilus in response to environmental metals. Funded under the Biological Sciences program (CFDA 47.074), the two-year award to Kennesaw State University will allow a postdoctoral fellow to identify the transcriptional regulatory networks for each of three ferric uptake regulator homologs in T. thermophilus. Using restriction endonuclease protection, selection,...