Epilepsy research program research partnership award

The Defense Health Agency awarded Oklahoma State University a $371,617 Block Grant under the Military Medical Research and Development program (CFDA 12.420) to conduct research related to epilepsy. The award will support a 3-year project focused on two key objectives:

1. Improving prediction of post-traumatic epilepsy (PTE) by enhancing machine learning models using electronic health record data from the VA and other sources. This will involve data preprocessing, model training, and the use of techniques like federated learning.

2. Improving prediction of epilepsy treatment outcomes by leveraging time-series data from electronic health records to identify biological factors influencing drug response. The university will develop predictive models using recurrent neural networks to tailor treatment plans.

Additionally, the university will develop a prototype web application for the VA system to screen for PTE risk and validate the prediction algorithms. The University of Central Oklahoma will serve as a sub-awardee, contributing expertise in areas such as biomedical research and student support services.