Purchase Order 75N95023P00723
- Not listed
- The Department of Health and Human Services' National Institutes of Health National Center for Advancing Translational Sciences awarded a $391,467 firm fixed price purchase order to Pointcare Systems Inc. R&D Division, doing business as Chirosolve, to acquire 97 specified chemical compounds for NCATS' pre-clinical library in support of its antiviral initiative. The solicitation sought quotes for delivery of the chemical compounds to locations in the United States by September 2022, with...
- The National Institute on Drug Abuse awarded a $101,000 firm fixed-price purchase order to Chemogenics Biopharma, LLC on September 16, 2025, for synthesis and bioanalytical analysis services supporting the National Center for Advancing Translational Sciences (NCATS) Early Translational Branch Chemistry Program. The contract, which extends through July 15, 2026, is performable in Durham, North Carolina. This procurement does not utilize a small business set-aside designation. The work involves...
- The Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences awarded a $19,800 firm fixed price purchase order to Karebay Biochem Inc., a for-profit small business, to synthesize 200 grams of compound NCGC00413972. This order supports NIH's biomedical research programs, particularly in the areas of drug discovery and infectious disease. Karebay Biochem has received multiple prior purchase orders from NIH entities to...
- This is a $249,500 firm fixed-price purchase order awarded by the Department of Health and Human Services' National Institutes of Health National Institute on Drug Abuse to Chemogenics Biopharma, LLC, a small business. The contract is for synthesis and bioanalytical analysis support services related to the therapeutic areas of the microbiome, neurodegeneration, and addiction. The services will augment existing medicinal chemistry campaigns within the National Center for Advancing Translational...
- This is a $36,000.00 firm fixed-price contract awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which is part of the National Institutes of Health (NIH), a civilian agency. The contract was awarded to Entrechem SL, a for-profit manufacturer located in Spain, to provide 100g each of two specialized chemical compounds, (1S,2S)-trans-N-Boc-Tetrahydro-3,4-furandiamine and (1R,2R)-trans-N-Boc-Tetrahydro-3,4-furandiamine. These compounds are needed as starting...
- This is a $90,075 firm fixed price purchase order contract awarded by the National Center for Advancing Translational Sciences (NCATS), a component of the U.S. Department of Health and Human Services, to American Biochemicals Inc. The contract is for the synthesis of approximately 50 analogs of the small molecule compound metarrestin, which is being developed as an anti-metastasis agent for pancreatic cancer. The goal is to reduce the brain exposure of the compounds while maintaining their...
- This is a firm fixed-price purchase order awarded by the Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences to A1 Biochem Labs LLC, a small business, for the purchase of 34 intermediate chemical compounds in 5g quantities with purity greater than 95%. The total potential value of the award is $112,350.00. This requirement was set aside for total small business participation and is part of the agency's Coronavirus COVID-19...
- This is a firm fixed-price purchase order awarded by the National Center for Advancing Translational Sciences (NCATS), a component of the National Institutes of Health (NIH), to Cellmosaic, Inc., a small disadvantaged business, for the synthesis and delivery of 100g of the lead NNMT inhibitor compound '960 over a 12-month period. The total contract value is $45,000.00. The award was made through a non-competitive, commercial item acquisition under FAR Parts 13 and 12, as Cellmosaic was...
- This is a $19,842.88 firm fixed-price purchase order awarded to Ipharmasupports LLC, a small business subchapter S corporation, by the National Institutes of Health (NIH) Clinical Center. The contract is for the provision of advanced radiosynthesis and radiochemical services, including the supply of F-DOPA synthesis sets, disposable cassettes, radiolabeling services, chemical synthesis equipment, preventative maintenance for radiosynthesis modules, and specialized medical research equipment like...
- This is a firm fixed price purchase order awarded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), to Chiral Technologies Inc., a foreign-owned, for-profit manufacturer of goods. The $6,015.00 contract is for the procurement of a Chiralcel OD-H semi-preparative chromatography column, which is used for chiral separations and analysis in biomedical research. Chiral Technologies Inc. is a specialized supplier of advanced...
This firm fixed-price purchase order, valued at $10,900, was awarded by the Department of Health and Human Services' National Institutes of Health National Center for Advancing Translational Sciences to Pointcare Systems Inc. R&D Division, doing business as Chirosolve, for the synthesis of tert-butyl (R)-3-(5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)piperidine-1-carboxylate in a 75 gram quantity with over 95% purity. The solicitation sought synthesis and delivery of the specified intermediate compound to support a project aiming to identify inhibitors of nicotinamide N-methyltransferase for treating ovarian cancer. Key deliverables under the contract include developing the chemical synthesis route, scaling up production, and reporting on characterization establishing purity over 95%. The award is designated for total small business and will be performed in India from September 2023 through December 2023.
Name | Description | Solicitation Number | FederalAgency | Type | PostedDate |
|---|---|---|---|---|---|
Synthesis of tert-butyl (R)-3-(5-oxo-4, 5-dihydro-1H-1, 2, 4-triazol-3-yl)piperidine-1-carboxylate in 75 gram quantity. | 75N95023Q00639 | Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse | Solicitation 2/2 | 8/24/23, 9:30 AM | |
Synthesis of tert-butyl (R)-3-(5-oxo-4, 5-dihydro-1H-1, 2, 4-triazol-3-yl)piperidine-1-carboxylate | 75N95023Q00639 | Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse | Special Notice 1/2 | 8/16/23, 10:44 AM |
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| P00001 | Supplemental Agreement for work within scope | $10.0k | 12/27/23 | |
| Not listed | Not listed | $10.9k | 9/7/23 |