Purchase Order 75N95022P00672

This is a $90,414 firm fixed-price purchase order awarded by the National Center for Advancing Translational Sciences (NCATS), a civilian agency within the Department of Health and Human Services, to Insphero Inc., a foreign-owned, for-profit manufacturer of 3D cell culture technologies and in vitro models. The contract is for a Liver Assay in Liver Spheroids to evaluate the toxicity of short interfering RNA (siRNA) and antisense oligonucleotides (ASOs), which are increasingly being used as...

The Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences (NCATS) awarded a $150,000.00 firm fixed-price purchase order to 3Dnamics Inc., a biotechnology company, for services related to the differentiation and characterization of induced pluripotent stem cell (iPSC) lines. This non-competitive commercial item acquisition was conducted under simplified acquisition procedures without a small business set-aside. The services...

This firm-fixed-price purchase order contract was awarded by the National Institute on Drug Abuse, a civilian agency within the U.S. Department of Health and Human Services, to Insphero Inc., a foreign-owned, for-profit manufacturer of advanced 3D cell culture technologies. The $46,829.63 contract tasks Insphero with providing 3D liver microtissues composed of human primary hepatocytes and other liver cells, which are used for drug-induced liver injury assays and toxicity testing. These...

This is a Small Business Innovation Research (SBIR) Phase I contract awarded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), to Mimetas US Inc., a self-certified small disadvantaged business. The $224,998 Firm Fixed Price contract is for the "Development and Evaluation of the HepaPlate IPS: A High Throughput Organ on a Chip IPS Hepatotoxicity Screening Platform." The contract aims to develop and evaluate a high-throughput organ-on-a-chip...

The National Center for Advancing Translational Sciences (NCATS), a civilian agency within the U.S. Department of Health and Human Services, awarded a $75,000.00 firm-fixed-price purchase order to Insphero Inc., a foreign-owned for-profit manufacturer of advanced 3D cell culture products. The contract is for safety assessment studies using Insphero's human, mouse, and rat 3D liver spheroid models to evaluate drug-induced liver injury (DILI) as part of the DILIPLUS assay program. This contract...

The National Center for Advancing Translational Sciences (NCATS), a civilian agency within the Department of Health and Human Services, has awarded a $96,829.63 firm-fixed-price purchase order to Insphero Inc., a foreign-owned, for-profit manufacturer of 3D cell culture technologies. The contract is for a Transcriptomics study - RNA-seq in Liver Spheroids Phase One, with the purpose of evaluating the safety and liver toxicity of candidate antisense oligonucleotides using a 3D liver microtissue...

This purchase order contract was awarded by the National Institutes of Health's National Center for Advancing Translational Sciences to Life Technologies Corporation for the delivery of 50 vials of human spheroid-qualified hepatocytes. As described in the original solicitation, these liver cells will support the National Institute on Drug Abuse's Antiviral Program for Pandemics by enabling the continued identification of direct-acting antivirals and development of microphysiological systems...

Insphero, Inc. has been awarded a firm fixed price purchase order valued at twenty-two thousand eight hundred dollars from the Department of Health and Human Services' National Institutes of Health National Center for Advancing Translational Sciences. The contract calls for Insphero to provide 3D liver microtissues composed of human primary hepatocytes and liver cells for drug testing and safety assessments. Insphero will deliver the 3D liver spheroids to support drug-induced liver injury assays...

This federal contract award, valued at $34,276.75, was issued by the National Institute on Drug Abuse (NIDA), a civilian agency within the Department of Health and Human Services (HHS), to Insphero Inc., a foreign-owned, for-profit manufacturer of 3D cell culture technologies and in vitro models. The contract is for the delivery of 3D liver microtissues composed of human primary hepatocytes, liver endothelial cells, and Kupffer cells, which will be used by NIDA's 3D Tissue Bioprinting Laboratory...

The Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences awarded a $45,717 firm fixed price purchase order to Xenotech LLC, doing business as Sekisui-Xenotech, for the provision of cryopreserved human, mouse, and rat hepatocytes. The solicitation sought these hepatocytes for use in drug metabolism experiments to support the National Institute on Drug Abuse's malaria research project and understand drug metabolism in...