This is a $24,900 firm-fixed-price purchase order awarded by the Department of Health and Human Services' National Institutes of Health (NIH) National Center for Advancing Translational Sciences to 3Dnamics Inc., a biotechnology company that provides stem cell engineering technology and related services. The contract is for the differentiation of induced pluripotent stem cells (iPSCs) into hepatocyte organoids, which are three-dimensional cell cultures that model liver tissue. This work supports...
The Department of Health and Human Services (HHS) National Institutes of Health (NIH) National Center for Advancing Translational Sciences (NCATS) awarded a $135,997 firm-fixed price purchase order to Fujifilm Cellular Dynamics, Inc. to provide induced pluripotent stem cell (iPSC)-derived human midbrain floorplate dopaminergic (iCell DopaNeurons) and glutamatergic (iCell GlutaNeurons) neurons. These fully differentiated neurons will be used in a 3D in vitro circuitry model to evaluate...
The Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences awarded a $287,502 firm fixed price purchase order to Fujifilm Cellular Dynamics, Inc. to provide induced pluripotent stem cell-derived neuronal and endothelial cells. The solicitation sought these cell types on a non-competitive basis from the incumbent contractor to maintain consistent data for ongoing biofabrication of three-dimensional tissue models in the Stem...
The National Center for Advancing Translational Sciences (NCATS), a civilian agency within the Department of Health and Human Services, has awarded a $96,829.63 firm-fixed-price purchase order to Insphero Inc., a foreign-owned, for-profit manufacturer of 3D cell culture technologies. The contract is for a Transcriptomics study - RNA-seq in Liver Spheroids Phase One, with the purpose of evaluating the safety and liver toxicity of candidate antisense oligonucleotides using a 3D liver microtissue...
This purchase order awards Fujifilm Cellular Dynamics, Inc. $349,700 for induced pluripotent stem (iPS) cell-derived differentiated cells to support the National Center for Advancing Translational Sciences within the National Institutes of Health's National Institute on Drug Abuse. The contract delivers over 300 units of various iPS cell-derived differentiated cells to develop three-dimensional tissue models of the brain. A pre-solicitation notice sought capability statements for a potential...
This contract was awarded by the Department of Health and Human Services' National Institutes of Health (NIH) National Institute on Drug Abuse to Applied Stemcell, Inc., a minority-owned, woman-owned small business, for a firm-fixed-price purchase order in the amount of $63,000.00. The contract calls for the use of CRISPR gene editing technology to create two custom induced pluripotent stem cell (iPSC) reporter cell lines - one with dual gene knock-ins for albumin and alpha-fetoprotein, and...
The National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health (NIH), awarded a $86,251 firm-fixed-price purchase order to Fujifilm Cellular Dynamics, Inc. to provide cryopreserved human induced pluripotent stem cell (iPSC)-derived neurons and related supplements. This non-competitive, brand-name acquisition is intended to support neurotoxicity screening assays. The requirement includes iCell DopaNeurons, iCell GlutaNeurons, and other neuronal cell...
This is a firm fixed-price purchase order awarded by the Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences (NCATS) to Fujifilm Cellular Dynamics, Inc., a manufacturer of biologically relevant human cells derived from induced pluripotent stem (iPS) cells. The order includes 50 units of the iCell Astrocytes Kit 01434, 20 units of the iCell DopaNeurons Kit 01279, 10 units of the iCell DopaNeurons Kit 01279, and 40 units of...
The Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse awarded a $509,165.70 firm-fixed-price purchase order to Government Scientific Source Inc. for the delivery of a Mass Cytometry Imaging System. This system will be used by the National Center for Advancing Translational Sciences (NCATS) Stem Cell Translation Laboratory to support their research on induced pluripotent stem cells. The contract is not set aside for any special business...
The Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences (NCATS) awarded a $142,843.00 firm-fixed-price purchase order to Hesperos, Inc., a leading company in organ-on-a-chip technology, to provide scientific testing services. The contract is for the target validation and therapeutic evaluation of drug compound TRND00601748-01 in NGLY1 deficient cell-based models, including motoneurons and neuromuscular junction models. This...
The Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences (NCATS) awarded a $150,000.00 firm fixed-price purchase order to 3Dnamics Inc., a biotechnology company, for services related to the differentiation and characterization of induced pluripotent stem cell (iPSC) lines. This non-competitive commercial item acquisition was conducted under simplified acquisition procedures without a small business set-aside. The services include generating and characterizing hepatocyte organoids, hepatic stellate cells, and hepatic bile duct organoids from 4 iPSC lines derived from patients with Alagille syndrome and 2 wild-type control iPSC lines. The goal is to study the disease phenotypes associated with this rare, multi-system disorder to facilitate therapeutic development.