Liquid Handlers with Bar Code Readers, Software and accessories
(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is 75N95019Q00066 and the solicitation is issued as a Request for Quotation (RFQ) on a Full and Open competitive basis. This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures; FAR Subpart 13.5-Test Program for Certain Commercial Items; and FAR Part 12-Acquisition of Commercial Items and is expected to exceed the simplified acquisition teshold of $250,000.00. A Fixed-Price type of contract is contemplated for any resulting contract entered as a result of this solicitation. (iii) The solicitation document and incorporated provisions and clauses are those in effect tough Federal Acquisition Regulation (FAR) Federal Acquisition Circular (FAC) Number/Effective Date: 2019-01 / 01-22-2019. (iv) The North American Industry Classification System (NAICS) code for this procurement is 334516 Analytical Laboratory Instrument Manufacturing with size standard 1,000 employees. (v) Background The National Institutes of Health (NIH) is the nation's leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. The National Center for Advancing Translational Sciences (NCATS) is a translational science center whose mission is to catalyze the generation of innovative methods and technologies that will enhance the development, testing and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions. NCATS is equipped with several acoustic dispensing instruments. These instruments can transfer small volumes of liquid (in the nL range) from a source plate to a destination of plate of any well density. These capabilities have enabled the establishment of Matrix screening where multiple compounds or drugs are screened against one another in a dose response fashion. Over time this has become a standard method of screening at NCATS and is one of the core technologies provided by the Research Service and Support (RSS) group. The adoption of acoustic dispensing has grown beyond just being used for Matrix screening to a variety of other applications, increasing the need for a diverse set of instruments to keep up with the growing demand. This demand became even more pressing upon completion of the NIH Small Molecule Repository contract (HHSN271201200003I) with the work previously being performed by Evotec Inc. and now becoming the responsibility of NCATS. A key piece of equipment put into use during the contract was a LabCyte Echo acoustic dispenser which has now become a critical component of a variety of RSS operations involving the creation of assay ready plates. This growing demand has led to the need for additional acoustic dispensers not just for assay ready plates but to be used as a general laboratory instrument for assay development projects beyond just being used to dispense small molecules solubilized in DMSO but nearly any aqueous media. Purpose and Objective: The purpose of this requirement is to obtain one (1) High-toughput tube-enabled system with Liquid Handlers and barcode readers and accessories on a BRAND-NAME-OR-EQUAL basis to the Echo655T and Echo655 and accessories manufactured by Labcyte, Inc located at 170 Rose Orchard Way, San Jose, CA, 95134. Product Description: Products offered must include those salient physical, functional, or other characteristics that are deemed essential in meeting the government's needs. Specifically, the following are considered the salient characteristics for this requirement: 1. Capable of dispensing directly from storage tubes which are acoustically qualified. 2. Supports a variety of reagent types; including DMSO, PCR and qPCR reagents, synthetic biology reagents, NGS reagents, primers and probes, cell culture media, proteins, nucleic acids, up to 50% glycerol, serum, plasma, antibodies, enzymes, and protein crystallography reagents. 3. Not require any reagent specific calibration. 4. Transfers multiple fluid types and volumes from one plate into another plate enabling rapid assay creation from one source plate. 5. Capable of up dispensing over 750,000 samples/day. 6. Must be a completely non-contact dispenser; not requiring tips, nozzles, or pin tools during fluid transfer eliminating the possibility of samples adhering to the tips, tip carryover, or tip leachates entering the sample. 7. Transfers samples acoustically from a source plate to an inverted destination plate transferring reagents in One-well-to-one-well for plate replication in 384 and 1536 well patterns; One-well-to-many-wells for distributing solutions to destination plates containing 1 - 3456 wells or target locations; Any-well-to-any-well enabling cherry picking, hit picking, and reformatting of solutions to destination plates containing 1 - 3456 wells or target locations. 8. Capable of continuous 24/7 operation. 9. Includes Echo expansion software, or equivalent, for cherry picking and IC50 via a standard, non-custom interface with ability to manipulate cherry picking. Covered by the manufacturers basic warranty in accordance with standard commercial warranty practice, including inside delivery after receipt of an order and installation and training. This requirement includes obtaining on a Brand-Name or Equal basis the following product specifications listed with the following unit quantity, manufacturer Part Number and unit description. LABCYTE ECHO 655T. The Echo 655T supports sample transfer directly from storage tubes (acoustic) or Echo qualified source plates to enable fully non-contact liquid handling workflows from sample storage all the way to assay-ready plates. 1.00 ECHO655T-ScrnOmics Includes 1 Echo 655T Liquid Handler with barcode readers (set of 2, for short side reads), Installation Kit, chiller, and 1 CD containing ECHO 3.0 server software, user manual, Screening and Omics2 Liquid Class, and a Standard Drop Placement Verification Test. Omics2 includes the transfer of aqueous based fluid types including buffers, proteins, and nucleic acids from Echo qualified 96-tube rack, 384 well Polypropylene (PP) 2.0 and 384 Low Dead Volume (LDV) source plates. Screening2 enables the transfer of 70-100% DMSO from ECHO qualified 96-tube rack, 384 well Polypropylene (PP) 2.0, 384 well Low Dead Volume (LDV), and 1536 well Low Dead Volume (LDV) source plates. 1.00 ECHO-Reformat1.7 Echo Plate Reformat Software 1.7 1.00 ECHO-IC501.7 Echo Dose-Response Software 1.7 1.00 001-12164 Air compressor for use with the Echo 555, 550, 520, and 525 Liquid Handlers 1.00 Client PC, Echo, Echo Client Computer, Operating system: Microsoft Windows 7 32-bit OS, CPU: Intel CoreTM XE2 i5-4570S 2.9 GHz Processor, Memory: 4GB RAM, Hard drive storage: 1 TB hard drive, Video Resolution: 1280 x 1024 resolution, Ethernet: 2 Gigabit 10/100/1000 base T Ethernet port (2 Ethernet Cards, Accessories: Microsoft Office 2016, Monitor, 22", DVI-D/DP/VGA, Dell USB Keyboard, Black, Dell MS111 USB Optical Mouse, OptiPlex and Fixed Precision, Labcyte Mousepad. 1.00 ECHO-V014 Dual Voltage Vacuum Pump 115/230VAC LABCYTE ECHO 655. The Echo 655 contains a new feature that eliminates the need for plate adaptor inserts found in previous generation Echo 55X Liquid Handlers thereby simplifying the swapping of plate types particularly when integrated into an automated workflow. 1.00 ECHO655-ScrnOmics Includes: 1 Echo 655 Liquid Handler with barcode readers (set of 2, for short side reads), Accessory Kit, Chiller,1 USB drive containing ECHO v3 Server Software and user manual, and Screening and Omics Liquid Classes. The Omics2 liquid class includes the transfer of aqueous based fluid types from Echo Qualified 384-well Polypropylene (PP) 2.0 and 384-well Low Dead Volume (LDV) source plates. Scrn2 liquid class enables the transfer of 70-100% DMSO from Echo Qualified 384-well Polypropylene (PP) 2.0, 384 well Low Dead Volume (LDV), and 1536-well Low Dead Volume (LDV) source plates. 1.00 ECHO-IC501.7 Echo Dose-Response Software 1.7 1.00 ECHO-Reformat1.7 Echo Plate Reformat Software 1.7 1.00 001-12164 Air compressor for use with the Echo 555, 550, 520, and 525 Liquid Handlers 1.00 Client PC, Echo, Echo Client Computer, Operating system: Microsoft Windows 7 32-bit OS, CPU: Intel CoreTM XE2 i5-4570S 2.9 GHz Processor, Memory: 4GB RAM, Hard drive storage: 1 TB hard drive, Video Resolution: 1280 x 1024 resolution, Ethernet: 2 Gigabit 10/100/1000 base T Ethernet port (2 Ethernet Cards) Accessories: Microsoft Office 2016, Monitor, 22", DVI-D/DP/VGA, Dell USB Keyboard, Black, Dell MS111 USB Optical Mouse, OptiPlex and Fixed Precision, Labcyte Mousepad. 1.00 ECHO-V014 Dual Voltage Vacuum Pump 115/230VAC 1.00 001-15657 Echo SDK Version, May 2018 Access Workstation integrating two (2) Echo units to allow automated loading and unloading of each Echo. Each Access Workstation will have a NEW Echo 655 and a currently installed Echo 525 (E5XX-1761 or E5XX-1777). The Echo units will be on turn-tables to allow the Echo to be used in stand-alone mode. Full details with pictures and diagrams to be included. 2.00 ACC-700 Access Workstation Base. Includes: Robot, Gripper, Base plate, 4 Plate Stack/Rack mounts , Insert Station, Temporary Hotel, Computer, Communication Accessories, Safety Enclosure, Tempo Software, 1 year warranty, Integration and Installation. 2.00 MISC-ACCESS Second Echo LHS iKit - 001-16420 iKit, 2nd ETT, LHS 2.00 ACC-1002 32" Table with Echo turn table attached. Used when upgrading a Base Access 64" system to an Access with Extension system plus a turn table. 2.00 ACC-1002 32" Table with Echo turn table attached. Used when upgrading a Base Access 64" system to an Access with Extension system plus a turn table. 2.00 ACC-786 Ergotron Keyboard and Monitor Arm. Does NOT include installation. 8.00 ACC-710 Random Access Rack. 20-shelf random access plate storage rack, removable and interchangeable. 2.00 ACC-706 2D/ID barcode reader for Access Workstation. 2.00 ACC-712 Lid Removal Station. Four shelves with vacuum based microplate delidding 2.00 ECHO-Reformat1.6 Echo Plate Reformat Software 1.6 2.00 ACC-725 32" x 36" Automation Table with Casters to support the Echo Liquid Handler on an Access system. Table also used for rear Echo integration 2.00 ECHO655-ScrnOmics Includes: 1 Echo 655 Liquid Handler with barcode readers (set of 2, for short side reads), Accessory Kit, Chiller,1 USB drive containing ECHO v3 Server Software and user manual, and Screening and Omics Liquid Classes. The Omics2 liquid class includes the transfer of aqueous based fluid types from Echo Qualified 384-well Polypropylene (PP) 2.0 and 384-well Low Dead Volume (LDV) source plates. Scrn2 liquid class enables the transfer of 70-100% DMSO from Echo Qualified 384-well Polypropylene (PP) 2.0, 384 well Low Dead Volume (LDV), and 1536-well Low Dead Volume (LDV) source plates. 2.00 ECHO-IC501.6 Echo Dose-Response Software 1.6 2.00 001-12164 Air compressor for use with the Echo 555, 550, 520, and 525 Liquid Handlers. 2.00 ECHO-V014 Dual Voltage Vacuum Pump 115/230VAC 2.00 MISC-ACCESS Upgrade package to include software and hardware changes and associated labor necessary to upgrade from Echo Applications 1.6 / Tempo 1.6 to Echo Applications 1.7 / Tempo 2.0 when and if available. 2.00 MISC-ACCESS Echo 65X Turntable Integration - 001-16442, IKIT, 2ND ECHO, 65X, TURNTABLE 1.00 001-10003 Enables the transfer of 70-100% DMSO from ECHO qualified 384 well Polypropylene (PP), 384 well Low Dead Volume (LDV), and 1536 well Low Dead Volume (LDV) source plates. Upgrade includes the hardware, calibrations, and Echo server software needed to run the Screening 2 calibrations. Hardware includes gripper stages, power components, transducer power supply components, and fluidics. Repairs to parts not listed above will require an additional purchase order for parts and labor. 1.00 001-10003 Enables the transfer of 70-100% DMSO from ECHO qualified 384 well Polypropylene (PP), 384 well Low Dead Volume (LDV), and 1536 well Low Dead Volume (LDV) source plates. Upgrade includes the hardware, calibrations, and Echo server software needed to run the Screening 2 calibrations. Hardware includes gripper stages, power components, transducer power supply components, and fluidics. Repairs to parts not listed above will require an additional purchase order for parts and labor. 1.00 001-10002 Enables the transfer of aqueous based fluid types including buffers, proteins, surfactant, glycerol solutions up to 50% v/v, and nucleic acids from ECHO qualified 384 well Polypropylene (PP) and 384 well Low Dead Volume (LDV) source plates. Upgrade includes the hardware, calibrations, and Echo server software needed to run the Omics 2 calibrations. Hardware includes gripper stages, power components, transducer power supply components, and fluidics. Repairs to parts not listed above will require an additional purchase order for parts and labor. 1.00 001-10002 Enables the transfer of aqueous based fluid types including buffers, proteins, surfactant, glycerol solutions up to 50% v/v, and nucleic acids from ECHO qualified 384 well Polypropylene (PP) and 384 well Low Dead Volume (LDV) source plates. Upgrade includes the hardware, calibrations, and Echo server software needed to run the Omics 2 calibrations. Hardware includes gripper stages, power components, transducer power supply components, and fluidics. Repairs to parts not listed above will require an additional purchase order for parts and labor. Shipping and handling cost must be included in any quotation submitted in response to this solicitation. Offerors must indicate if any applicable extended warranty coverage is only offered at time of purchase in accordance with the Offeror's standard commercial practice, or if warranty may be tendered on an optional year basis, priced on a per annum basis, for a total contract warranty period term not to exceed five (5) years. If Offeror's standard commercial warranty is less than five years, offeror shall also include pricing for extended warranty coverage/preventive maintenance, for a total period of up to five (5) years. In accordance with FAR Clause 52.217-7 OPTION FOR INCREASED QUANTITY-SEPARATELY PRICED LINE ITEM, the following optional quantities are applicable to this requirement. All new Echo units and Application Software packages come with a full one-year warranty. The following are for 3 additional service contracts on all new Echos, Access Workstations and Application Software (3 x Echo 655, 2 x Access Workstations, 1 x Echo 655T, EDR and EPR x4) as optional quantities to extend the term of the warranty. 9.00 LSA-555-Gold Term: 1 Year Includes the following: One annual preventative maintenance visit. Unlimited phone, email, and remote support sessions. All parts, site labor, zone charges and per diem charges. Software bug fixes for Echo user interface software and applications software. The initial service response time is not to exceed (8) business hours. The onsite service response time will not exceed (3) business days after all remote diagnostic sessions have been exhausted and both parties agree a service visit is required. Instrument eligibility: 1-6 years post manufacturing date. All parts and services retain a (90) day warranty from the date of installation. Instrument recertification is required if the service contract has lapsed. 3.00 LSA-655T-Gold Term: 1 Year Includes the following: One annual preventative maintenance visit. Unlimited phone, email, and remote support sessions. All parts, site labor, zone charges and per diem charges. Software bug fixes for Echo user interface software and applications software. The initial service response time is not to exceed (8) business hours. The onsite service response time will not exceed (3) business days after all remote diagnostic sessions have been exhausted and both parties agree a service visit is required. Instrument eligibility: 1-6 years post manufacturing date. All parts and services retain a (90) day warranty from the date of installation. Instrument recertification is required if the service contract has lapsed. 12.00 LSA-EPR Term: 1 Year Software Maintenance Contract - Echo Plate Reformat 12.00 LSA-EDR Term: 1 Year Software Maintenance Contract - Echo Dose Response 6.00 LSA-ACCBase-Gold Term: 1 Year Labcyte Service Agreement - Gold Level - Access Base. This agreement covers all Labcyte provided components of an Access system. Integrated third party devices are not covered. Delivery, Inspection and Acceptance: Offerors should indicate an estimated delivery time in full after receipt of an order and any other training or factory warranty schedules in accordance with standard commercial practice, or as applicable. Inspection and acceptance will be performed at a Government facility located at 9800 Medical Center Drive, Rockville, MD 20850. The Government expected build time and delivery is 84 days after contractor receipt of any contract resulting from this solicitation. (vi) The provision at FAR clause 52.212-1, Instructions to Offerors - Commercial Items, applies to this acquisition. The following is provided as an addendum to FAR clause 52.212-1, Instructions to Offerors: Installation and any onsite training should be quoted on separate line items. Shipping and handling cost must be included in any quotation submitted in response to this solicitation. Offerors should indicate an estimated delivery time in full after receipt of an order and any other training or warranty schedules applicable. Offerors must indicate if any applicable extended warranty coverage (EWC) is only offered at time of purchase in accordance with the Offeror's standard commercial practice, and the length of time of such warranty. SMALL BUSINESS SUB CONTRACTING PLAN: The HHS SUBCONTRACTING PLAN TEMPLATE is attached to this solicitation. Pursuant to NIH's priority of Small Business participation, Offerors shall be required to submit a subcontracting plan in accordance with the terms of the clause entitled "Small Business Subcontracting Plan," at FAR Clause No. 52.219-9 prior to contract award. (vi) The provision at FAR clause 52.212-2, Evaluation - Commercial Items, applies to this acquisition. The following is an addendum to 52.212-2. Responses received to this RFQ will be evaluated on the basis of Lowest Price Technically Acceptable (LPTA). Offeror's submitting a response must provide a completed Price Quote to be evaluated and considered for award. Price quotes must indicate fixed unit pricing and total cost, including shipping cost and estimated time of delivery after receipt of order, and warranty and training considerations. Responses will be evaluated based on contractor's ability to meet the government's SALIENT CHARACTERISTICS stated in this notice and on ability to deliver required supplies. Responses to this solicitation must include clear and convincing evidence of the Offeror's capability of fulfilling the requirement as it relates to the essential government requirements stated in this solicitation. Under the lowest-price technically acceptable (LPTA) process, Offerors' will be determined to be "technically acceptable" or "technically unacceptable" based on an evaluation of responses against the following factors to determine if, as submitted, the proposal is technically acceptable. (1) Technical Capability: Offerors shall clearly indicate possessing the capability to achieve the essential salient characteristic features of this requirement. The Offeror must indicate in its quotation the ability to provide all of the requirements. The Offeror must indicate in its quotation the ability to meet the delivery requirements. Offerors submitting a response with documented technical specifications and evidence of possessing the technical knowledge, qualifications and capability and management structure needed in successfully achieving this requirement will be determined to be technically acceptable. (2) Corporate Experience: Demonstrated capability to accomplish contract requirements and extent of relevant experience in the areas covered by the Purchase Description. The Government shall evaluate quotations based on projects that are similar in size, scope, and complexity to the requirements contained in this solicitation. Respondents that believe that they are manufacturers or authorized resellers of any BRAND-NAME product specified in this announcement must provide, as part of their response: (a) product, catalog, model, and/or part number(s); (b) product description; (c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the purchase description; quantity; estimated price or cost; shipping, handling, and/or installation charges; and delivery date after receipt of order. (vii) The provision at FAR Clause 52.212-3, Offeror Representations and Certifications Commercial Items, applies to this acquisition. (viii) The provision at FAR Clause 52.212-4, Contract Terms and Conditions-Commercial Items, applies to this acquisition. An addendum to FAR Clause 52.212-4, Contract Terms and Conditions-Commercial Items, Offeror Representations and Certifications Commercial Items, applies to this acquisition. The addendum includes the following FAR Clauses, provisions, terms and conditions: (a) 52.211-6 Brand Name or Equal (Aug 1999); (b) 52.217-7 Option to Increase Quantity as a separately priced line item (Mar 1989). (ix) The provision of FAR Clause 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items applies to this acquisition and the clause at 52.22251, Exemption from Application of the Service Contract Act to Contracts for Maintenance, Calibration, or Repair of Certain EquipmentRequirements (Nov 2007) (41 U.S.C. 351, et seq.) applies to this acquisition. See attached for the appendix to 52.212-5. In addition, the following FAR provisions are applicable to this solicitation and incorporated by reference: 52.204-7 System for Award Management (Oct 2018), 52.204-13 System for Award Management Maintenance (Oct 2018), 52.204-16 Commercial and Government Entity Code Reporting (Jul 2016), 52.204-18 Commercial and Government Entity Code Maintenance (Jul 2016). (x) The clause at FAR 52.219-9, Small Business Subcontracting Plan is applicable to this order. If the awardee is an other than small business, the awardee shall be required to submit a commercial subcontracting plan prior to contract award. (xi) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. (xii) Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The PRICE QUOTE shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. Responses to this solicitation must include clear and convincing evidence of the offeror's capability of fulfilling the requirement as it relates to the technical evaluation criteria and a price proposal. Offerors must include a completed copy of the provision at 52.212-3, Offeror Representations and Certifications Commercial Items, with their offer, or provide a copy of the valid certifications registrations and Representation and Certifications from the System of Award Management (SAM) applications at www.SAM.gov, which may be indicated on the Offeror's cover sheet. In addition, the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." All responses must be received no later than the date specified in this announcement. Late responses will not be accepted. All responses must reference the subject solicitation number. Responses must be submitted electronically to hunter.tjugum@nih.gov. Facsimile responses will not be accepted. For information regarding this solicitation, contact Hunter Tjugum by email at hunter.tjugum@nih.gov or by phone at 301-827-5304.. 75N95019Q00066 Department of Health and Human Services National Institutes of Health
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