Synthesis of self amplifying nucleic acid constructs encoding poultry antigen and their encapsulation into lipid nanoparticles to generate protective immunity following vaccination of poultry. The…
Active Purchase Order Awarded Last action
- Contract number
- 1232SA26P0092
- Awardee
-
Vectorbuilder Inc. UEI CLRZY7CGLVM1
- Awarding agency
-
Central Program Planning Coordination and Support
Agricultural Research Service, Department of Agriculture
- Obligated
- $20,305
Award facts
- Opportunity
-
- Synthesis of Self-Amplifying Nucleic Acid Constructs Solicitation · 1232SA26Q0044 · Posted Dec 16, 2025
- Contract value 100% obligated
- $20,305.00 Current and potential, with all options
- Completion date 96% complete
- Current and potential, with all options
- Contracting staff
- Funding agency
- Agricultural Research Service Department of Agriculture
- NAICS code
- 541380 Testing Laboratories and Services
- Set-aside
- Total Small Business
- Competition
- Competed under SAP · 2 offers Simplified Acquisition
- Pricing
- Firm Fixed Price
- Place of performance
- Chicago, IL 60609, USA
- Legislative mandates
-
- Service Contract Act FAR subpart 22.10
Award details come from SAM.gov/FPDS.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Supplemental Agreement for work within scope | $0 | |
| Original award | $20,305 |
About this award
The U.S. Department of Agriculture's Agricultural Research Service (USDA ARS) awarded a $20.3K purchase order to Vectorbuilder Inc., a Chicago-based biotechnology firm specializing in molecular biology and gene delivery services. The contract, awarded on March 3, 2026, with completion targeted for November 2, 2026, funds the synthesis of self-amplifying RNA constructs encoding poultry antigens and their encapsulation into lipid nanoparticles to develop a protective vaccine for poultry. The award is designated as a Total Small Business Set-Aside, limiting competition to small business concerns, and represents a firm fixed-price engagement reflecting the lowest price technically acceptable proposal.
Under this contract, Vectorbuilder Inc. will deliver five lipid nanoparticle-encapsulated self-amplifying RNA constructs based on Venezuelan equine encephalitis virus genetic components, including codon optimization for avian expression, gene synthesis, plasmid cloning, in vitro transcription, and RNA encapsulation into SM10 lipid nanoparticles. The work requires comprehensive quality control assessments and delivery of specified RNA aliquots with minimum yield requirements within 30 days of award. This engagement leverages Vectorbuilder's established expertise in custom virus packaging and molecular cloning services, which the company has previously provided to NIH institutes and other federal agencies, supporting the USDA ARS's broader mission to advance agricultural research and disease prevention in poultry production.
Description
Synthesis of self amplifying nucleic acid constructs encoding poultry antigen and their encapsulation into lipid nanoparticles to generate protective immunity following vaccination of poultry. The vaccine is designed to protect poultry against infect
Quick answers
Who was awarded contract 1232SA26P0092?
1232SA26P0092 was awarded to Vectorbuilder Inc. by Central Program Planning Coordination and Support (Agricultural Research Service) on March 3, 2026.
How much is contract 1232SA26P0092 worth?
The government has obligated $20,305 on 1232SA26P0092.
Which agency awarded contract 1232SA26P0092?
Central Program Planning Coordination and Support (Agricultural Research Service) awarded 1232SA26P0092, with funding from Agricultural Research Service (Department of Agriculture).
Was contract 1232SA26P0092 competed?
The extent of competition for 1232SA26P0092 was competed under sap. The government received 2 offers. It was set aside: Total Small Business.
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