Grant For Research 80NSSC19K0708
- Not listed
- The National Aeronautics and Space Administration (NASA) awarded a $198,354.38 grant for research to the Regents of the University of Colorado, doing business as the University of Colorado Office of Contracts and Grants Division. This university-led project aims to systematically characterize changes in microbial cell growth dynamics, aggregation, drug resistance, and virulence across simulated micro-, lunar (1/6 g), and Martian (1/3 g) gravity environments. The research will utilize spaceflight...
- NASA awarded a $744,428.59 research grant to Weill Medical College of Cornell University on January 25, 2022, to support the Space Biology Program's investigation into how spaceflight and microgravity affect biological organisms. The project utilizes advanced molecular analysis technologies including spatial transcriptomics, single-nucleus RNA-sequencing, and multi-omic spatial mapping to examine gene expression changes and cell signaling pathways in microorganisms, plants, and animals exposed...
- The Regents of the University of Colorado has received a $439,767 research grant from the National Aeronautics and Space Administration (NASA) through its Shared Services Center, with performance in Boulder, Colorado. The award is effective January 1, 2026, and is scheduled for completion by December 31, 2027. This grant supports the Research Opportunities in Space and Earth Sciences (ROSES) funding opportunity, which aims to execute a balanced science program aligned with guidance from the...
- Colorado State University's Sponsored Programs Division was awarded a $1.605 million research grant by a civilian federal agency to investigate telomere length dynamics and DNA damage responses in astronauts during long-duration deep space missions. The study aims to establish temporal profiles of human telomere length as a biomarker for health and aging-related risks in astronauts exposed to unique environmental stressors including microgravity and galactic cosmic radiation. This research...
- The Regents of the University of Colorado received a $225,000 grant award from a civilian federal agency (Shared Services Center) on September 25, 2024, for research scheduled to conclude by September 30, 2025. The research initiative focuses on understanding and mitigating the impacts of communication delays on team performance and coordination within the context of future NASA Artemis missions. Specifically, the work will examine how 5-14 second lunar communication delays affect team...
- This $281,194.84 federal research grant was awarded by the National Aeronautics and Space Administration (NASA) to the Regents of the University of Colorado, doing business as the University of Colorado, to investigate whether microbial life existed on a young Mars. The 4-year grant, awarded on August 1, 2019 with a completion date of July 31, 2023, will fund fundamental research to expand scientific knowledge on the potential development of life beyond Earth. The University of Colorado, an...
- The Regents of the University of Colorado, operating through its Office of Contracts and Grants Division, received a $299,834.50 firm fixed-price delivery order from NASA's Johnson Space Center on July 25, 2024, to support research on the effect of metabolic supplements on muscle regeneration under microgravity conditions. Work will be performed in Boulder, Colorado, with an ultimate completion date of February 28, 2026. This delivery order was issued without a set-aside designation,...
- The University of Colorado, through its Office of Contracts and Grants Division, has been awarded a $3.19 million firm fixed-price delivery order by NASA's Johnson Space Center to develop induced pluripotent stem cell-derived chimeric antigen receptor T-cell (iPSC-derived CAR-T) therapies manufactured in space environments for clinical applications. The work will be performed in Boulder, Colorado, with an ultimate completion date of December 15, 2028. This delivery order is issued under a larger...
- The National Aeronautics and Space Administration (NASA) awarded a $139,819.93 grant to Weill Medical College of Cornell University (doing business as Joan & Sanford I Weill Medical College of Cornell University) to conduct research on spaceflight-induced gene expression changes. The grant, titled "OUR PROPOSED EXPERIMENTS WILL ENHANCE OUR UNDERSTANDING OF SPACEFLIGHT-INDUCED GENE EXPRESSION CHANGES BY PERFORMING SINGLE-CELL RNA-SEQUENCING AND SPATIAL RNA-SEQUENCING ON MOUSE TISSUES...
- The Regents of the University of Colorado, operating through its Office of Contracts and Grants Division in Boulder, Colorado, was awarded a $507,000 firm fixed-price delivery order on January 17, 2023, to provide mission integration and operations support for the MABL-B (Mesenchymal Stem Cells in Microgravity-Induced Bone Loss) investigation. This delivery order is issued under the university's larger $15 million Indefinite Delivery Contract with NASA's Johnson Space Center for Low Earth...
The Regents of The University of Colorado received a $522,774.39 research grant awarded on May 1, 2019, by a civilian federal agency to conduct a systematic investigation of how space radiation, microgravity, and their combined effects impact cellular function. The project utilizes a molecularly barcoded yeast genome-wide knockdown collection as a model organism system, leveraging the fact that approximately 70 percent of yeast's essential genes share significant human homologs. The experimental design includes samples flown aboard NASA's Orion Space Exploration Mission 1 (EM-1) beyond the Van Allen Belts to experience both microgravity and space radiation exposure, complemented by equivalent cultures aboard the International Space Station (ISS) within the Space Automated Bioproduct Lab (SABL) incubator system, and ground-based controls. Temperature variation studies will be conducted to isolate the thermal component of the EM-1 flight conditions, with all work based in Boulder, Colorado and completing by December 31, 2024. The primary objectives of this research initiative are to identify metabolic and genomic pathways affected by microgravity exposure, space radiation, and the combination of both environmental stressors using quantitative molecular barcode analysis to measure relative fitness of each mutant strain. This work supports NASA's expanding human spaceflight mission architecture by characterizing fundamental biological responses to deep space conditions, thereby informing medical countermeasures and understanding genetic factors that determine organism resilience in extraterrestrial environments. The award was not designated as a set-aside contract and represents a collaborative scientific effort aligned with federal priorities in human space exploration and life sciences research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | ($5) | 12/4/25 | ||
| P00010 | Funding Only Action | ($5) | 12/4/25 | |
| P00009 | Other Administrative Action | $0 | 3/19/24 | |
| Not listed | $0 | 3/19/24 | ||
| Not listed | $0 | 6/7/23 |