To prepare for future human exploration missions far from earth, NASA s space biology program is seeking to build a better understanding of the effects of spaceflight and zero gravity on the biology…

Ended Grant For Research Awarded Last action

Contract number
80NSSC22K0254
Awardee
Awarding agency
Obligated
$744,429

Award facts

Contract value 100% obligated
$744,428.59 Current and potential, with all options
Completion date 100% complete
Current and potential, with all options
Contracting staff
NAICS code
Not on record
Set-aside
No set-aside
Competition
Full and Open Competition Basic Research
Pricing
Other
Place of performance
New York, NY 10065, USA

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Funding Only Action P00007 -$183
Funding Only Action P00006 $220,945
Funding Only Action P00005 · Spatiotemporal mapping of the impact of spaceflight on the heart and brain $213,768
Funding Only Action P00004 $111,131
Funding Only Action P00003 $56,768
Funding Only Action P00002 · Spatiotemporal mapping of the impact of spaceflight on the heart and brain $107,000
Other Administrative Action P00001 $0
Original award $35,000

About this award

NASA awarded a $744,428.59 research grant to Weill Medical College of Cornell University on January 25, 2022, to support the Space Biology Program's investigation into how spaceflight and microgravity affect biological organisms. The project utilizes advanced molecular analysis technologies including spatial transcriptomics, single-nucleus RNA-sequencing, and multi-omic spatial mapping to examine gene expression changes and cell signaling pathways in microorganisms, plants, and animals exposed to spaceflight conditions aboard the International Space Station and ground-based analog experiments. The research addresses a National Research Council recommendation to study the biological effects of both short and long-duration spaceflight across multiple organism categories, with the ultimate goal of understanding impacts on human health during future exploration missions far from Earth.

The grant, which carries a completion date of November 30, 2024, employs complementary omics analysis platforms including 10X Genomics Visium and NanoString's GeoMx technology to conduct rigorous molecular studies on rodent organs and tissues. This work represents a significant advancement in space biology research capability, enabling scientists to dissect gene expression at the single-cell level, analyze cell-to-cell interactions, and generate the first in-vivo human-microbial interaction maps from spaceflight data. The contract is a non-set-aside award and is not associated with a larger contract vehicle. As a child entity of Cornell University, Weill Medical College has extensive experience managing federally funded research across biomedical domains and holds substantial National Institutes of Health grant portfolios.

Description

To prepare for future human exploration missions far from earth, NASA s space biology program is seeking to build a better understanding of the effects of spaceflight and zero gravity on the biology of microorganisms, plants and animals in spacecraft

Quick answers

Who was awarded contract 80NSSC22K0254?

80NSSC22K0254 was awarded to Weill Medical College Of Cornell University by Shared Services Center (National Aeronautics and Space Administration) on January 25, 2022.

How much is contract 80NSSC22K0254 worth?

The government has obligated $744,429 on 80NSSC22K0254.

Was contract 80NSSC22K0254 competed?

The extent of competition for 80NSSC22K0254 was full and open competition.

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