Grant For Research 80NSSC19K0434
- Not listed
- Texas A&M AgriLife Research, a research division of the Texas A&M University System, was awarded a grant valued at approximately $600K to investigate telomere dynamics and oxidative stress in Arabidopsis within the space radiation environment. The research project, designated 21-21SBPS_2-0029, commenced on November 21, 2022, with completion expected by November 20, 2026, and will be conducted at the awardee's facility in College Station, Texas. No set-aside designation was applied to...
- This $750,000.00 grant contract was awarded by the National Aeronautics and Space Administration (NASA) to The Trustees of the University of Pennsylvania, doing business as Clinical Practices of the University of Pennsylvania. The grant supports research on the effects of weightlessness and radiation exposure on telomere length in skeletal muscle atrophy, which has relevance to the health of astronauts during space exploration missions. The research aims to define the underlying molecular...
- NASA awarded a $744,428.59 research grant to Weill Medical College of Cornell University on January 25, 2022, to support the Space Biology Program's investigation into how spaceflight and microgravity affect biological organisms. The project utilizes advanced molecular analysis technologies including spatial transcriptomics, single-nucleus RNA-sequencing, and multi-omic spatial mapping to examine gene expression changes and cell signaling pathways in microorganisms, plants, and animals exposed...
- NASA's Ames Research Center awarded a $1.105 million firm fixed-price definitive contract to Rensselaer Polytechnic Institute on February 2, 2023, to determine the effects of spaceflight on cell and tissue dysfunction along the brain-liver-gut axis and to characterize the role of these perturbations in accelerating tissue degeneration associated with aging. Performance is located in Troy, NY. The award derives from a multi-agency Research Announcement issued May 27, 2021, by NASA, NIH, HHS...
- This is a grant awarded by the National Aeronautics and Space Administration (NASA) to KBR Wyle Services, LLC, a for-profit manufacturer, to conduct research on the effects of long-duration spaceflight on astronauts. The research aims to determine whether spaceflight factors such as radiation, psychological stress, and altered physical activity contribute to the accelerated progression of atherosclerosis. The study will measure biomarkers, arterial structure and function, and genomic and...
- This is a $277,796.43 doctoral research project awarded by the Shared Services Center, a civilian federal agency, to the Regents of the University of Colorado (CU). The contract is focused on developing a framework and model to evaluate the mortality risk and performance degradation of astronaut crew members due to space radiation and other spaceflight stressors like microgravity. This work aims to address NASA's need for tools to reduce uncertainty in radiation effects on human health and...
- The National Aeronautics and Space Administration (NASA) awarded a $149,575.99 grant to the University of Arizona for a ground-based New Space Biology research project. The project will investigate the epigenetic effects of ionizing radiation and microgravity on gene expression related to DNA damage response and cell cycle control in human mammary epithelial cells. The research aims to better understand how the space environment can alter endocrine regulation of these cellular processes. This...
- This is a $2,399,358.99 grant awarded by the National Aeronautics and Space Administration (NASA) to Emory University in Atlanta, Georgia to conduct research on the health effects of exposure to galactic cosmic radiation (GCR). The research aims to better understand the mechanisms by which GCR, particularly its high charge and energy (HZE) particle components, can lead to chronic DNA damage and impairment of DNA repair machinery, which may contribute to increased cancer risk for astronauts on...
- Duke University's Office of Research Administration has been awarded an $800,000 research grant by the NASA Shared Services Center, with a completion date of November 30, 2026. This non-set-aside grant supports a multi-disciplinary investigation into the cardiovascular effects of environmental stressors encountered during space exploration, specifically examining the individual and combined impacts of galactic cosmic radiation and weightlessness on cardiac biology. The research leverages two...
- Arizona State University (ASU), through its Office of Research and Sponsored Projects Administration, received a $1.12M research grant from a civilian federal agency to conduct a two-aim investigation into how spaceflight analogue culture conditions affect microbial pathogenesis and host-pathogen interactions. Aim 1 focuses on characterizing microbial stress responses and pathogen colonization in three-dimensional tissue co-culture models containing immune cells exposed to spaceflight analogue...
Colorado State University's Sponsored Programs Division was awarded a $1.605 million research grant by a civilian federal agency to investigate telomere length dynamics and DNA damage responses in astronauts during long-duration deep space missions. The study aims to establish temporal profiles of human telomere length as a biomarker for health and aging-related risks in astronauts exposed to unique environmental stressors including microgravity and galactic cosmic radiation. This research leverages methodologies pioneered in the NASA Twins Study and First One Year Mission, applying telomere length and cytogenetic measures across the integrated One Year Mission Project aboard the International Space Station and a concurrent ground-based analog component involving prolonged isolation. The contract, awarded January 31, 2019, with an ultimate completion date of December 31, 2027, carries no set-aside designation. The research is designed to identify adaptive trends in human health and performance during extended low-Earth orbit operations by measuring how telomere shortening reflects the combined effects of individual genetic susceptibilities, lifestyle stresses, and environmental exposures encountered during spaceflight. Shorter telomeres are associated with increased risk of age-related pathologies including immune dysfunction, dementia, cardiovascular disease, and cancer, making telomere dynamics a particularly informative health metric. Additionally, telomeres serve critical functions in maintaining genomic integrity by protecting chromosomal ends and preventing inappropriate DNA damage responses. Colorado State University, a prominent Land Grant research institution headquartered in Fort Collins, serves as the prime contractor and regularly executes complex research and technical services projects for federal agencies across scientific and technical domains.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 2/12/26 | ||
| P00018 | Other Administrative Action | $0 | 2/12/26 | |
| P00017 | Funding Only Action | $25.0k | 3/21/25 | |
| Not listed | $25.0k | 3/21/25 | ||
| Not listed | $180.0k | 3/14/25 |