NHLBI Program Project Applications (P01 Clinical Trials Optional)

Closed Posted

Opportunity number
PAR-24-065
Agency
Applications due
Award size
Not on record

Opportunity facts

Funding instrument
Grant
Category
  • Health
Eligible applicants
  • Higher Education Inst. (Public)
  • Other
  • Independent School Districts
  • Higher Education Inst. (Private)
  • County Governments
  • Small Businesses
  • Public or Indian Housing Auth.
  • 501(c)(3) Nonprofits
  • For Profit Organizations
  • Special District Governments
  • Tribal Governments (Federally Recognized)
  • Non-501(c)(3) Nonprofits
  • Tribal Organizations (Not Federally Recognized)
  • State Governments
  • City/Township Governments
Points of contact
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institutes of Health National Heart, Lung, and Blood Institute (NHLBI) is soliciting applications for Program Project Grants (P01) supporting collaborative research on cardiovascular, lung, and blood diseases, transfusion medicine, blood resources, and sleep disorders, with applications due September 25, 2026. Applicants must propose a minimum of three interrelated research projects investigating a complex biomedical theme aligned with NHLBI's mission, and may include core units and a project led by an Early Stage Investigator.

Eligible applicants include higher education institutions (public and private), nonprofits (501(c)(3) and non-501(c)(3)), small businesses, for-profit organizations, state and local governments, tribal governments (federally recognized and not federally recognized), tribal organizations, county governments, special district governments, and public or Indian housing authorities. Additional eligible applicants include HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, tribally controlled colleges and universities, faith-based and community-based organizations, regional organizations, and U.S. territories or possessions. Non-domestic entities are ineligible; however, non-domestic components of U.S. organizations and foreign components as defined in the NIH Grants Policy Statement are permitted.

No cost share or matching requirement is stated in the opportunity announcement. Award ceiling, award floor, and number of awards are not specified. Period of performance and place of performance are not specified in the source material.

The program funds fundamental research, implementation science, health disparities, and translational research. NHLBI explicitly encourages new scientific directions and views the P01 mechanism as an opportunity to attract scientists not traditionally supported by the Institute and to develop emerging scientific leaders.

Applications are reviewed by an appropriate initial review group (study section) and receive secondary review by the National Heart, Lung, and Blood Advisory Council. Evaluation criteria assess scientific merit and significance, technical adequacy of experimental design, investigator competency, adequacy of facilities and resources, budget necessity, and relevance to NHLBI objectives.

The opportunity is assigned to five federal grant programs: Lung Diseases Research (CFDA 93.838), Cardiovascular Diseases Research (CFDA 93.837), Blood Diseases and Resources Research (CFDA 93.839), Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders (CFDA 93.840), and National Center on Sleep Disorders Research (CFDA 93.233).

Synopsis

The National Heart, Lung, and Blood Institute (NHLBI) Program Project Grant (P01) supports research related to fundamental processes and diseases of the heart, blood and lymphatic vessels, lungs, and blood, including transfusion medicine, blood resources, and sleep disorders other programs including implementation science, health disparities, and translation research that address the mission of the Institute. This FOA requires a minimum of three interrelated research projects that investigate a complex biomedical theme or research question. The projects may be supported by core units, if justified, to facilitate economy of effort, space, and equipment. The NHLBI provides support for Program Project Grants (PPGs) in the belief that collaborative research efforts can accelerate the acquisition of knowledge more effectively than a simple aggregate of research projects that have no interaction or thematic integration. NHLBI is particularly interested in encouraging new scientific directions in PPGs. Use of the P01 activity code is viewed as an opportunity to attract scientists who have not traditionally been supported by the NHLBI. Further, the PPG environment presents an opportunity for emerging scientific leaders to gain insight into how to lead a successful scientific Program, and applicants will have the opportunity to include a project led by an Early Stage Investigator (ESI). All projects in the Program must be interrelated and have objectives that address a central theme within the scientific mandate of the NHLBI.

Eligibility

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Files

File Type Posted
PKG00289315.pdf PDF
PAR-24-065-Full-Announcement.html HTML file
PKG00283838.pdf PDF

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