Antigens Predicted for Broad Viral Efficacy through Computational Experimentation (APECx)
Closed Solicitation Posted
- Solicitation number
- 75N99224R00001
- Agency
- National Institutes of Health Department of Health and Human Services
- Responses due
- Set-aside
- No set-aside
Opportunity facts
- NAICS code
- 541714 Research and Development in Biotechnology (except Nanobiotechnology)
Notice details come from SAM.gov. Updated .
About this opportunity
This solicitation notice seeks proposals to advance the development of broadly protective viral antigens through computational methods under the Antigens Predicted for Broad Viral Efficacy through Computational Experimentation (APECx) program. The Department of Health and Human Services National Institutes of Health Advanced Research Projects Agency for Health will administer multiple awards to support research objectives including high-throughput analysis, in silico antigen design, and preclinical vaccine evaluation. Proposals are due February 16, 2024 and will be evaluated based on technical approach, impact, management plan, and capabilities. Interested parties were required to submit an abstract by December 1, 2023 for consideration to submit a full proposal by the January 19, 2024 deadline.
There is no set-aside designated for this opportunity. It is anticipated multiple awards will be made through cooperative agreements or other transaction agreements over five years to support activities under NAICS code 541715 and PSC code R425. Proposals must demonstrate capabilities across viral antigen characterization, computational modeling, and vaccine assessment. Budget submissions should follow the cost proposal templates provided to estimate costs for the initial 36-month phase and subsequent 24-month phase. Place of performance will be at recipients' locations within the United States.
Notice text
5 versions
Update #5 · Latest ·
The purpose of Amendment No. 4 is to provide the correct SF424A spreadsheet, titled "75N99224R00001 - SF424A Cost Proposal Spreadsheet UPDATED VERSION" for proposers submitting proposals for cooperative agreements. Cooperative Agreement proposals are to be submitted to Grants.gov.
As a reminder, proposals are invite-only and a proposal must have been requested to submit a proposal for this solicitation.
Please ensure to follow this opportunity for any further updates.
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The purpose of Amendment No. 3 is to provide the SF424A Cost Proposal Spreadsheet for proposers submitting proposals for cooperative agreements. In addition, for the purpose of clarity, the amendment renames the previous cost proposal spreadsheet to Other Transaction Cost Proposal Spreadshseet. The Other Transaction Cost Proposal Spreadsheet is for proposers submitting proposals for other transactions.
As a reminder, proposals are invite-only and a proposal must have been requested to submit a proposal for this solicitation.
Please ensure to follow this opportunity for any further updates.
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The purpose of Amendment No. 2 is to provide the cost proposal spreadsheet template.
As a reminder, proposals are invite-only and a proposal must have been requested to submit a proposal for this solicitation.
Please ensure to follow this opportunity for any further updates.
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The purpose of Amendment No. 1 to the APECx RDS is to extend the abstract due date to December 15, 2023 at 9:00 AM ET and to extend the proposal due date to February 16, 2024 at 5:00 PM ET. Additional minor changes to the RDS are highlighted in yellow. A revised RDS is attached to this amendment.
As a reminder, proposals will be invite-only and an abstract must be submitted to be invited to submit a proposal. Please ensure to follow this opportunity for any further updates.
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The Advanced Research Projects Agency for Health (ARPA-H) posts this funding opportunity in support of its Antigens Predicted for Broad Viral Efficacy through Computational Experimentation (APECx) Program. ARPA-H anticipates multiple awards and award types will result from this announcement.
Interested parties are invited to review attached APECx Research & Development Solicitation No. 75N99224R00001. Abstracts are due December 1, 2023, 9:00 AM ET. Proposals will be invite-only and will be due January 19, 2024, 5:00 PM ET. An abstract must be submitted to be invited to submit a proposal.
Please ensure to follow this opportunity for any updates.
For more information about APECx, please visit https://arpa-h.gov/engage/programs/apecx/.
Please note that the APEX Accelerators government contracting resource for small businesses notice is included on all SAM.gov postings and is unrelated to the ARPA-H APECx program.
Update #4 ·
The purpose of Amendment No. 3 is to provide the SF424A Cost Proposal Spreadsheet for proposers submitting proposals for cooperative agreements. In addition, for the purpose of clarity, the amendment renames the previous cost proposal spreadsheet to Other Transaction Cost Proposal Spreadshseet. The Other Transaction Cost Proposal Spreadsheet is for proposers submitting proposals for other transactions.
As a reminder, proposals are invite-only and a proposal must have been requested to submit a proposal for this solicitation.
Please ensure to follow this opportunity for any further updates.
-----------------------------------------------------------------------------------------------------------------------
The purpose of Amendment No. 2 is to provide the cost proposal spreadsheet template.
As a reminder, proposals are invite-only and a proposal must have been requested to submit a proposal for this solicitation.
Please ensure to follow this opportunity for any further updates.
-----------------------------------------------------------------------------------------------------------------------
The purpose of Amendment No. 1 to the APECx RDS is to extend the abstract due date to December 15, 2023 at 9:00 AM ET and to extend the proposal due date to February 16, 2024 at 5:00 PM ET. Additional minor changes to the RDS are highlighted in yellow. A revised RDS is attached to this amendment.
As a reminder, proposals will be invite-only and an abstract must be submitted to be invited to submit a proposal. Please ensure to follow this opportunity for any further updates.
-----------------------------------------------------------------------------------------------------------------------
The Advanced Research Projects Agency for Health (ARPA-H) posts this funding opportunity in support of its Antigens Predicted for Broad Viral Efficacy through Computational Experimentation (APECx) Program. ARPA-H anticipates multiple awards and award types will result from this announcement.
Interested parties are invited to review attached APECx Research & Development Solicitation No. 75N99224R00001. Abstracts are due December 1, 2023, 9:00 AM ET. Proposals will be invite-only and will be due January 19, 2024, 5:00 PM ET. An abstract must be submitted to be invited to submit a proposal.
Please ensure to follow this opportunity for any updates.
For more information about APECx, please visit https://arpa-h.gov/engage/programs/apecx/.
Please note that the APEX Accelerators government contracting resource for small businesses notice is included on all SAM.gov postings and is unrelated to the ARPA-H APECx program.
Update #3 ·
The purpose of Amendment No. 2 is to provide the cost proposal spreadsheet template.
As a reminder, proposals are invite-only and a proposal must have been requested to submit a proposal for this solicitation.
Please ensure to follow this opportunity for any further updates.
-----------------------------------------------------------------------------------------------------------------------
The purpose of Amendment No. 1 to the APECx RDS is to extend the abstract due date to December 15, 2023 at 9:00 AM ET and to extend the proposal due date to February 16, 2024 at 5:00 PM ET. Additional minor changes to the RDS are highlighted in yellow. A revised RDS is attached to this amendment.
As a reminder, proposals will be invite-only and an abstract must be submitted to be invited to submit a proposal. Please ensure to follow this opportunity for any further updates.
-----------------------------------------------------------------------------------------------------------------------
The Advanced Research Projects Agency for Health (ARPA-H) posts this funding opportunity in support of its Antigens Predicted for Broad Viral Efficacy through Computational Experimentation (APECx) Program. ARPA-H anticipates multiple awards and award types will result from this announcement.
Interested parties are invited to review attached APECx Research & Development Solicitation No. 75N99224R00001. Abstracts are due December 1, 2023, 9:00 AM ET. Proposals will be invite-only and will be due January 19, 2024, 5:00 PM ET. An abstract must be submitted to be invited to submit a proposal.
Please ensure to follow this opportunity for any updates.
For more information about APECx, please visit https://arpa-h.gov/engage/programs/apecx/.
Please note that the APEX Accelerators government contracting resource for small businesses notice is included on all SAM.gov postings and is unrelated to the ARPA-H APECx program.
Update #2 ·
The purpose of Amendment No. 1 to the APECx RDS is to extend the abstract due date to December 15, 2023 at 9:00 AM ET and to extend the proposal due date to February 16, 2024 at 5:00 PM ET. Additional minor changes to the RDS are highlighted in yellow. A revised RDS is attached to this amendment.
As a reminder, proposals will be invite-only and an abstract must be submitted to be invited to submit a proposal. Please ensure to follow this opportunity for any further updates.
-------------------------------------------------------------------------------------------------------------------------------
The Advanced Research Projects Agency for Health (ARPA-H) posts this funding opportunity in support of its Antigens Predicted for Broad Viral Efficacy through Computational Experimentation (APECx) Program. ARPA-H anticipates multiple awards and award types will result from this announcement.
Interested parties are invited to review attached APECx Research & Development Solicitation No. 75N99224R00001. Abstracts are due December 1, 2023, 9:00 AM ET. Proposals will be invite-only and will be due January 19, 2024, 5:00 PM ET. An abstract must be submitted to be invited to submit a proposal.
Please ensure to follow this opportunity for any updates.
For more information about APECx, please visit https://arpa-h.gov/engage/programs/apecx/.
Please note that the APEX Accelerators government contracting resource for small businesses notice is included on all SAM.gov postings and is unrelated to the ARPA-H APECx program.
Update #1 ·
The Advanced Research Projects Agency for Health (ARPA-H) posts this funding opportunity in support of its Antigens Predicted for Broad Viral Efficacy through Computational Experimentation (APECx) Program. ARPA-H anticipates multiple awards and award types will result from this announcement.
Interested parties are invited to review attached APECx Research & Development Solicitation No. 75N99224R00001. Abstracts are due December 1, 2023, 9:00 AM ET. Proposals will be invite-only and will be due January 19, 2024, 5:00 PM ET. An abstract must be submitted to be invited to submit a proposal.
Please ensure to follow this opportunity for any updates.
For more information about APECx, please visit https://arpa-h.gov/engage/programs/apecx/.
Please note that the APEX Accelerators government contracting resource for small businesses notice is included on all SAM.gov postings and is unrelated to the ARPA-H APECx program.
Attachments
| File | Type | Posted |
|---|---|---|
| 75N99224R00001 - SF424A Cost Proposal Spreadsheet UPDATED VERSION.xlsx | XLSX spreadsheet | |
| 75N99224R00001 - Other Transaction Cost Proposal Spreadsheet.xlsx | XLSX spreadsheet | |
| 75N99224R00001 - SF424A Cost Proposal Spreadsheet.xlsx | XLSX spreadsheet | |
| 75N99224R00001 - Cost Proposal Spreadsheet.xlsx | XLSX spreadsheet | |
| 75N99224R00001 APECx Amd No. 1.docx | DOCX document | |
| 75N99224R00001 APECx.docx | DOCX document |
Notice history
| Notice | Type | Posted |
|---|---|---|
| Antigens Predicted for Broad Viral Efficacy through Computational Experimentation (APECx) | Solicitation | |
| Antigens Predicted for Broad Viral Efficacy through Computational Experimentation (APECx) | Pre-Solicitation | |
| Antigens Predicted for Broad Viral Efficacy through Computational Experimentation (APECx) Proposers' Day | Special Notice |
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