VS5718739-NOTICE OF INTENT-ACIVE MOTIF- FACTORPATH CHIP SEQ.pdf

NOTICE OF INTENT TO AWARD A SOLE SOURCE CONTRACT

Requisition No: VS5718739

Intended Source: Active Motif

Period of performance: September 1, 2020-August 31, 2021

Description of Requirement: FactorPath ChIP-Seq

This contract action is for the acquisition of supplies for which the Government intends to solicit and negotiate with only one source under the authority of Federal Acquisition Regulation (FAR) Subpart

13.106-1(b)(1). The National Institute of Environmental Health Science (NIEHS), Office of Acquisitions

(OA) intends to award a single source purchase order to Active Motif, 1914 Palomar Oaks Way, Suite

150, Carlsbad, CA 92008.

The Active Motif FactorPath ChIP-Seq Service is needed because defects in normal development during gestation can lead to disease states later in life. Specific cell signaling pathways to fully explore and understand how and why these types of diseases can occur. One method widely employed by the scientific community, ChIP-seq, is used to discern which genes make up these pathways and how they interact. ChIP-seq can identify areas of chromosomes which are bound by specific proteins and, thus, show different genes working together to produce an affect. By helping to map these pathways and build on the current knowledge of development of reproductive organs, this process will help to increase the chance that diseases will be identified early on and treatments can be found. The Reproductive

Developmental Biology Group at the NIEHS is currently using this method in the lab, therefore in order to have continuous results, this same method must be employed so that the results are not altered.

The applicable North American industry Classification System (NAICS) Code for this procurement is

621511 “Medical Laboratories.” Its associated Business Size Standard is $35000000.00.

Line item 1. 25001-FactorPath ChIP-Seq, 2 samples with 4 antibodies each. (Qty.8 each)

Line item 2. 25046- Input-Seq- Qty. 4 each)

Period of performance: September 1, 2020-August 31, 2021.

NIEHS will solicit and negotiate directly with Active Motif and no solicitation will be issued. This notice of intent is not a request for competitive proposals or quotations; however, all responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency. Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. A determination by the

Government not to compete this proposed requirement based on responses to this notice is solely within the discretion of the Government. Interested parties must express their interest and must be submitted in writing via email to Valarie K. Sims at sims3@niehs.nih.gov and are due by 10:00a.m., July 11, 2020. No faxed documents will be accepted. If no responsive statements are received by the due date, an award will be made to Active Motif.

http://www.sam.gov/ http://www.sam.gov/ mailto:sims3@niehs.nih.gov mailto:sims3@niehs.nih.gov