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SOURCES SOUGHT NOTICE

1. Solicitation Number: 75N95023Q00482

2. Title: Imager for Protein Analysis

3. Classification Code: 6640 Laboratory equipment and Supplies

4. NAICS Code: 334516 - Analytical Laboratory Instrument Manufacturing

5. Size Standard:1,000 employees

6. Description:

This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations.

The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition; and (4) availability of domestic sources manufactured in the United States in sufficient and reasonably available commercial quantities and of a satisfactory quality.

For equipment/supply requirements, responses must include the place of manufacturing (i.e. address if supply/equipment is a domestic end product and include country of manufacture). For equipment/supply requirements, small businesses must also address the size status of the manufacturer under the applicable NAICS code (i.e. address Non-Manufacturer Rule).

Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice.

This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only.

This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement.

This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement, to determine the method of acquisition, and availability of domestic sources manufactured in the United States in sufficient and reasonably available commercial quantities and of a satisfactory quality. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Small businesses are encouraged to respond.

Purpose and Objectives: The NIDA IRP Cellular Stress and Inflammation (CSI) is looking to procure a new imaging system to examine protein through western blotting and other assays. CSI was established for the purpose of studying the role of endoplasmic reticulum (ER) stress and inflammation in neuronal dysfunction caused by substance abuse or neurodegenerative diseases. Protein analysis is an essential technique for the CSI examine and quantify target proteins. The current imaging Li-Cor system was acquired over a decade ago and needs to be replaced with a more functional imaging system. The replacement system will be shared with the Hope laboratory and Genetic Engineering and Viral Vector Core.

Generic Product Name: Imager for Protein Analysis

Project requirements: A Capable Offeror must demonstrate its ability to provide the following brand name or equal items to the Government:

A Capable Offerors must demonstrate its ability to provide a system with the following brand name or equal Salient Characteristics:

· Must perform membrane quantitative westen blots

· Must perform membrane protein arrays

· Must perform gel EMSA/Gel shift assay

· Must perform gel glycoprotein staining

· Must perform gel nuclei acid gel imaging

· Must perform colorimetric and gluorescent get staining

· Must perform multi-well plate In-Cell western assay

· Must perform multi-well plate On-Cell western assay

· Must perform multi-well plate RNAi Analysis

· Must perform slide tissue section imaging

· Must perform slide protein arrays

· Must provide installation and training

· Must provide acquisition and data analysis software

A Capable Offerors must demonstrate its ability to provide a system with the following brand name or equal Technical Characteristics:

· Laser Lifetime: 40,000 hours typical.

· 700 Channel Laser Source: Solid-state diode laser at 685 nm. 800 Channel Laser Source: Solid-state diode laser at 785 nm. Detectors: Silicon avalanche photodiodes.

· Scanning Speed: 5-40 cm/s.

· Resolution: 21-337 µm.

· Focus: Adjustable to be aligned to the top surface of the scan bed up to 4 mm above the scan bed to obtain the best signal-to-noise ratio of sample in membranes, gels, or microplates.

· Dynamic Range: 4 logs (Manual); >6 logs (Auto).

· Operating Conditions: For indoor use only; operating temperature 15 - 35 °C and dew point not greater than 22 °C, non-condensing; altitude not to exceed 2000 m.

· Environmental Conditions: Pollution Degree 2.

· Power Requirements: Universal input range is between 100-240 VAC (voltage fluctuations not to exceed 10% of the nominal voltage); 4 Amp maximum; at 120V, 0.5 Amp typical when idle; 50/60 Hz.

· Dimensions: 37 H × 53 W × 62 D cm (15 H × 21 W × 24.5 D inches). With the hood fully open, the Odyssey DLx requires 74 cm (29”) of vertical clearance.

· Weight: 33 kg (72 lbs).

· Network Protocol: TCP/IP.

· Network Connection: Cat. 5e RJ45, 10BASE-T/100BASE-TX/1000BASE-T. Use only the supplied cable.

Quantity:

In case domestic sources are available and capable of fulfilling the Government’s need, and a future solicitation is published, the Government will use evaluation preferences in accordance with FAR 25.

Capability statement /information sought. Companies that believe they possess the capabilities to provide the required products should submit documentation of their ability to meet each of the project requirements to the Contracting Officer. The capability statement must specifically address each of the project requirements separately. Additionally, the capability statement should include 1) the total number of employees, 2) the professional qualifications of personnel as it relates to the requirements outlined, 3) any contractor GSA Schedule contracts and/or other government-wide acquisition contracts (GWACs) by which all of the requirements may be met, if applicable, and 4) any other information considered relevant to this program. Capability statements must also include the Company Name, Unique Entity ID from SAM.gov, Physical Address, and Point of Contact Information. The response must include the respondents’ technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses.

For equipment/supply requirements, responses must include the place of manufacturing (i.e. address if supply/equipment is a domestic end product and include country of manufacture). For equipment/supply requirements, small businesses must also address the size status of the manufacturer under the applicable NAICS code (i.e. address Non-Manufacturer Rule).

Interested companies are required to identify their type of business, applicable North American Industry Classification System (NAICS) Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number.

The information submitted may be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required.

All responses to this notice must be submitted electronically to the Contract Specialist. Facsimile responses are NOT accepted. The response must be submitted to Andrew Varley, Contract Specialist, at e-mail address Andrew.Varley@nih.gov.

The response must be received on or before July 17, 2023, at 1:00 PM, Eastern Time.

“Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work.

Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in www.sam.gov. However, responses to this notice will not be considered adequate responses to a solicitation.

Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).”