SON_Automated Liquid Handler Systems.pdf
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- Automated Liquid Handling Systems
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- SS-NIAID-24-2224319
About this file
This document is a Statement of Needs (SON) for the procurement of two automated liquid handling systems by the National Institute of Allergy and Infectious Diseases (NIAID), Vaccine Research Center (VRC), Vaccine Production Program (VPP).
The SON describes the technical requirements for the two systems - one for early phase purification development microchromatography with biolayer interferometry detection, and one for purification screening and upstream process development microchromatography. Key requirements include in-line integration with specified analytical equipment, compatibility with Tecan liquid handling scripts and hardware, precise pipetting capabilities, and specified facility requirements.
The related federal contract opportunity is a Sources Sought notice seeking information on qualified vendors that can meet the stated requirements. Responses are due by August 22, 2024, and an award is anticipated around September 20, 2024, with a delivery timeframe of 60-120 days. The notice states that only Original Equipment Manufacturer (OEM) products are acceptable, and requests information on the sustainability of the equipment.
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Other files
| File | Type | Posted |
|---|---|---|
| BOM_Automative Liquid Handling Systems.xlsx | XLSX spreadsheet |
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Attachment 1
7/18/2024, Version 1
Statement of Needs (SON) – Automated Liquid Handling Systems
This SON is for the procurement of two instruments/systems capable of the following:
1. Early phase purification development microchromatography liquid handler with biolayer interferometry detection:
• In-line integration with biolayer interferometry instruments o Agreement with the manufacturer of the biolayer interferometry instruments to ship a loaner to the awardee to do the integration of the two pieces of equipment.
• In-line integration with Tecan Spark spectrophotometers.
• Compatible with library of Tecan liquid handling scripts and Tecan Fluent Control.
• Compatible with Atoll RoboColumn pressurized microchromatography columns.
• Minimum of 8 channel simultaneous pipetting with disposable and fixed tips.
• Capacity of up to 1 mL per disposable pipetting channel, up to 0.5 mL fixed.
• Disposable pipet precision of 5 µL with ≤ 5% CV, fixed pipet precision of 20 µL with ≤ 5% CV.
• Programmable gripper capable of eccentric and concentric microplate and tool manipulation.
• Capacity for at least 20 SBS/SLAS footprint microplates.
• In-line integration with centrifuge capable of >6000 rcf.
• Capable of mounting Tecan EVO and Tecan Fluent deck carriers.
• Capable of future expansion to include thermostatting for at least two microplates or programmable thermocycler for single microplate.
• Facility Requirements:
o Weight: 800 lbs. or less (full loaded) o Space Clearance around instrument
Distance to object in rear of the instrument: 4-6 inches Outreach of the front safety panel: Maximum of 22 inches Outreach of the short (open) front safety panel: Maximum of 16 inches Distance to object in front of the instrument: Between 38-42 inches o Footprint of instrument Footprint Depth: maximum of 32 inches Overall Depth: 38 inches Overall Length: 85 inches
2. Purification screening and upstream process development microchromatography liquid handler:
• In-line integration with Tecan Spark spectrophotometers.
• Compatible with library of Tecan liquid handling scripts and Tecan fluent control.
• Compatible with Atoll RoboColumn pressurized microchromatography columns.
• Minimum 8 channel simultaneous pipetting with disposable and fixed tips.
• Capacity of up to 1 mL per disposable pipetting channel and up to 0.5 mL fixed.
• Disposable pipet precision of 5 µL with ≤ 5% CV, fixed pipet precision of 20 µL with ≤ 5% CV.
• Programmable gripper capable of eccentric and concentric microplate and tool manipulation.
• Capacity for at least 20 SBS/SLAS footprint microplates.
Attachment 1
7/18/2024, Version 1
• In-line integration with centrifuge capable of >6000 rcf.
• Capable of mounting Tecan EVO and Tecan Fluent deck carriers.
• Capable of future expansion to include thermostatting for at least two microplates or programmable thermocycler for single microplate.
• Facility Requirements:
o Weight: 800 lbs. or less (full loaded) o Space Clearance around instrument
Distance to object in rear of the instrument: 4-6 inches Outreach of the front safety panel: Maximum of 22 inches Outreach of the short (open) front safety panel: Maximum of 16 inches Distance to object in front of the instrument: Between 38-42 inches o Footprint of instrument Footprint Depth: maximum of 32 inches Overall Depth: 38 inches Overall Length: 65 inches
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