SAM Pre-Solicitation NICHD-23-072.pdf

NICHD-23-072

INTRODUCTION

THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A

CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION.

The National Institutes of Health, National Institute of Child Health and Development (NICHD), in support of the National Institute on Alcohol Abuse and Alcoholism (NIAAA), intends to award a purchase order without providing for full and open competition to 10X GENOMICS, INC. for Reagent sets and kits.

BACKGROUND

The pathogenesis of lung fibrosis remains partly an unexplored area of research. The team at SFD is focused to investigate the pathological mechanism that leads to pulmonary fibrosis. In this line of research, we have been able to identify multiple targets that have a prominent role in the development of lung fibrosis. In this order, we want to obtain reagents that will help us to prepare samples for the single-cell library. Next, we want to perform single-cell RNASeq with this library from different genetically modified mice. This will enable us to narrow down the sub-population of lungs that really contribute towards the development of pulmonary fibrosis.

JUSTIFICATION

These reagents by 10x Genomics have become an essential tool in our research as it enables the preparation of samples for the single-cell library from different groups. Our current 10X Genomics Chromium instrument is used for library preparation. The needed reagents are compatible with the instrument at the laboratory. To our knowledge, no other competitor company in the market has such a technology or alternative products that are compatible with this equipment.

NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE

The intended procurement is classified under NAICS code 325413 with a Size standards in number of employees: 1,250.

REGULATORY AUTHORITY

The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Regulation (FAR) Circular (FAC) 2023-01 effective 12/30/2022. This acquisition is conducted under the procedures as prescribed in FAR subpart 13-Simplified Acquisition Procedures at an amount not exceeding the simplified acquisition threshold ($250,000) and FAR Subpart 12- Acquisition of Commercial Items.

STATUTORY AUTHORITY

This acquisition is conducted under the authority of FAR 13.106(b)(1) Soliciting from a single source - For purchases not exceeding the simplified acquisition threshold.

PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS

NICHD-23-072

PLACE OF DELIVERY

NIH/NIAAA

5625 FISHERS LN, RM 2S-28,

Rockville, MD 20852 United States

DESCRIPTION OF REQUIREMENT

These reagent sets and kits are needed for single-cell library preparation from lung samples for single-cell RNA-Seq as part of ongoing research projects being conducted by SFD lab members.

CLOSING STATEMENT

This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability in response to this notice and may submit a capability statement, which shall be considered by the agency. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement.

A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement.

All respondents must have an active registration in the System for Award Management (SAM) www.sam.gov. All responses to this notice shall be submitted electronically by 5:00 PM Eastern Standard Time, on February 22nd, 2022 to jacob.balenson@nih.gov and shall include pre-solicitation # NICHD-23-072 in the subject line.

http://www.sam.gov/ mailto:jacob.balenson@nih.gov