JAX-mouse_New_BLANK_AP.docx

Streamlined Acquisition Plan

(For acquisitions greater than the micro-purchase threshold up to the simplified acquisition threshold)

Reference: HHS Directive for Acquisition Planning

REVIEW AND APPROVAL

Solicitation Number:

Recommended By:

Program Manager (PM) / Contracting Officer’s Representative (COR)

Approved By:

Contracting Officer (CO) or Purchasing Agent

1. STATEMENT OF NEED FAR 7.105(a)(1) Type of Acquisition:

☐ Supplies/Equipment (including IT equipment) ☐ Severable services ☒ Non-severable Services ☒R&D support services ☐Information technology (IT) support services ☐Other Background and Justification:

The Jackson Laboratory will generate and insert CRISPR Knock In plasmid, pCAG-Lox-STOP-Lox-mouse Adgrf1-IREStdTomato-bGHpolyA into the C57BL/6J mouse ROSA26 locus to enhance the Adgrf1 expression. This service includes plasmid design and reagent preparation (8-10 weeks), embryo manipulation (4-5 weeks) and founder identification (4-6 weeks), CRISPR breeding service and sperm cryopreservation. The Jackson Laboratory mice are the most well-characterized and widely used mice available, and once the sperm cryopreservation process has been completed, the straws of sperm will be maintained in liquid nitrogen storage in three separate tanks at The Jackson Laboratory.

2. COST FAR 7.105(a)(3) The total Independent Government Cost Estimate (IGCE), inclusive of options, is: $32,500.00

3. DELIVERY OR PERFORMANCE-PERIOD REQUIREMENTS FAR 7.105(a)(5) For Supplies/Equipment Anticipated Delivery Date: 9/2022 For Services Period of Performance:

Base:

Option 1*: $ N/A Option 2*: $ N/A Option 3*: $ N/A Option 4*: $ N/A

*A D&F must be attached for use of options. FAR 17.205

4. INHERENTLY GOVERNMENTAL FUNCTIONS FAR 7.105(b)(10) (For Services Only) ☒Not Applicable. In accordance with FAR 7.5 and the Office of Federal Procurement Policy Letter 11-01, this form serves as a written determination by the designated requirements official certifying that the services being procured under this acquisition are not inherently governmental. If the contractor is required to provide services, none will require the exercise of discretion in applying Government authority or the making of value judgments in making decisions for the Government.

☐Yes; this acquisition plan is for an inherently governmental function, or is closely associated with an inherently governmental function. An assessment will be conducted to determine if a government employee is required.

If Yes is selected above, please identify if this acquisition is for a critical government function and explain below.

☐Yes. ☐No.:

5. GOVERNMENT FURNISHED PROPERTY and INFORMATION: FAR 7.105(b)(15) /16) ☐ Government Furnished Property (GFP) and associated directives will be listed in the solicitation and provided for by clauses FAR 52.245-1, Government Property, and 52.245-9, Use and Charges. The contractor is obligated to report lost, stolen, or damaged Government property, as well as the disposition of the salvage.

☐ Government Furnished Information (GFI) will include mandatory Government publications and reporting procedures. The contractor will be given applicable NIH instructions. Potential offerors will be provided with any GFI necessary to make an offer in the RFQ. Additional information, if determined necessary, will be provided to potential offerors as required.

☒ GFP and GFI are not applicable.

6. ENVIRONMENTAL AND ENERGY CONSERVATION: FAR 7.105(b)(17) ☒ Environmental and energy conservation considerations are not applicable.

☐ The Performance Work Statement or Statement of Work requires compliance with the Resource Conservation and Recovery Act of 1976 (RCRA), the Clean Air Act (CAA), the Clean Water Act (CWA), the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA), the Toxic Substances Control Act, and all applicable Federal, State, and local environmental statutes and regulations. The acquisition encourages and allows for energy conservation measures to be taken.

7. Electronic and Information Technology (EIT) Accessibility Standards (508 Compliance). FAR 39.2 ☐ Yes. The contractor will be required to develop, procure, maintain, and/or use EIT and to ensure their EIT allows Federal employees and members of the public with disabilities to have access to, and use of, information and data comparable to the access and use by people without disabilities.

☒ No. This acquisition is not an EIT product or service. However, all electronic reports submitted shall be compliant with Section 508 of the Rehabilitation Act of 1973.

If section 508 applies, the requirements must include a list of applicable Section 508 accessibility standards from the United States Access Board 36 CFR Part 1194.

8. SOURCES FAR 7.105(b)(1) Indicate the prospective sources of supplies or services that can meet the need.

☐ UNICOR ☐ NIH FSS BPA ☐ NIH IDCs ☐ HHSSSI ☐ GSA FSS ☐ GWACs: (Specify source) ☒ Open market ☐ Other (Specify):

Will this be a small business set-aside?

☒ No.

☐ Yes. (Specify type of small business set-aside associated with this requirement) ☐ VOSB ☐ SDVOSB ☐ HUB Zone ☐ SDB ☐ WOSB ☐ 8(a) ☐ Small Business ☐ Not Applicable

9. COMPETITION FAR 7.105(b)(2) This procurement will be executed through:

☐ Full and Open Competition ☐ Full and Open Competition After Exclusion of Sources (small business set aside) ☒ Other than Full and Open Competition as follows:

☐ Brand Name Justification (FAR 6.302-1(c)) ☒ Single Sole Justification (FAR Part 13 - Simplified Acquisition Procedures) ☐ Limited Sources Justification (FAR Part 8 - Federal Supply Schedules) ☐ Justification and Approval (FAR Part 15- Contracting by Negotiation & FAR Subpart 6.3) ☐ Justification for Exception to Fair Opportunity (FAR Subpart 16.5 - Indefinite Delivery Contracts and Subpart 16.505—Ordering)

Note: If other than full and open competition, attach the justification to this plan.

10. CONTRACT TYPE SELECTION FAR 7.105(b) (3) Select all that apply:

☒ Fixed Price, or ☐ Cost Type: (Specify type) *A D&F must be attached with T&M/LH type contracts FAR 16.601(d)(1)(i) ** See FAR 16.5 for additional documentation requirements

11. OTHER RELEVANT FACTS FAR 7.105

Discuss any additional technical, business, management, or other significant considerations that will impact the acquisition:

Market Research Performed:

The CRISPR/Cas9 system is a modern technique in editing mouse genome. The Jackson Laboratory provides many Cas9 expressing mouse strains that have been successfully generated with LoxP and reporter insertions. Furthermore, the colony will be expanded and preserved with the characterization in the Jackson Laboratory Identify plan for inspection and acceptance:

The mice will be accepted by staff in the Lab of Molecular Signaling/NIAAA using PCR genotyping method.

12. LIST OF ATTACHMENTS

Select as appropriate:

☐ Statement of Work / Performance Work Statement / Statement of Need ☐ Delivery Schedule ☐ Independent Government’s Cost Estimate ☐ Market Research Results ☐ DHHS Small Business Review System (SBRS) Approval ☐ FBO Sources Sought Notice ☒ Justification for Other Than Full and Open Competition (All Forms) ☐ Determination & Findings for the Inclusion of Options ☐ Determination and Findings for T&M ☐ Source Selection or Technical Evaluation Criteria ☐ Information Security Clearance ☐ Contracting Officer’s Representative (COR), FAC-C Certification Certificate

STREAMLINED ACQUISITION PLAN

Micro-Purchase Threshold to Simplified Acquisition Threshold

SOURCE SELECTION SENSITIVE

FOR OFFICIAL USE, ONLY

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