SHINE_Streamlined_Cost_Buildup_Workbook_Amendment_1.xlsx

XLSX spreadsheet 36 KB Posted Sep 3, 2026

Attached to: Selective Harnessing of Intrinsic Neuroplasticity Engineering (SHINE)
Solicitation number: DARPA-PA-25-07-06
Issued by: Defense Advanced Research Projects Agency

About this file

Written by GovTribe AI · Sep 3, 2026

This is a Streamlined Cost Buildup Workbook template for the DARPA SHINE (Selective Harnessing of Intrinsic Neuroplasticity Engineering) program, specifically designed for proposals under Solicitation Number DARPA-PA-21-05 (referenced in the template version). The workbook is a fixed-price milestone-based budgeting tool for Other Transaction Prototype Agreements with a maximum award value of $2,000,000 per award, including both government funding and any required performer cost share.

The template structure requires proposers to build costs across an 18-month Phase 1 base period aligned with five milestone deliverables due at months 3, 6, 9, 12, and 18. Cost categories include direct labor (with hours and rates specified by labor category, excluding percent level of effort calculations), subcontractors and consultants, travel, and other direct costs—all fully burdened with indirect costs. All proposers, including universities and institutions of higher education, must provide actual labor hours and associated rates. The five milestones progress from establishing an experimental baseline and validation protocol (Month 3) through selective substrate localization (Month 6), target engagement verification (Month 9), circuit-selective neuroplasticity demonstration (Month 12), and culmination in a fully validated intervention prototype with technical documentation and end-to-end validation testing (Month 18). Payments are made solely in amounts specified in the milestone schedule, and proposers must provide detailed justification for all cost elements in Volume 2 of their price proposal.

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Other files

File	Type	Posted
SHINE_Amendment_1_Summary_of_Changes.docx	DOCX document	Sep 3, 2026
DARPA-PA-25-07-06-Amendment-01.pdf	PDF	Sep 3, 2026
Streamlined_Cost_Buildup_Workbook.xlsx	XLSX spreadsheet	Aug 28, 2026
DARPA-PA-25-07-06.pdf	PDF	Aug 28, 2026

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Summary

Cell Key:

Input

DARPA Solicitation Number:	Insert DO number
Proposal Number:	DARPA Proposal Number
Proposer:	Proposer's Name (Prime or Sub)
Prime Contractor	Prime (If Applicable)

	Total Months	Price per Phase
Phase 1 (Base)	18	$ - 0
TOTAL PRICE PROPOSED		$ - 0

Budget by Month Phase 1 Base

	NOTES/INSTRUCTIONS:
	1. The milestone due dates are stipulated in the Disruption Opportunity, and Attachment 1 Task Description Document and Attachment 3 Schedule of Milestones and Payments of the DO SAMPLE OT. The milestone amounts will be automatically populated from the sums in the "Milestone [X] Total" at the bottom of this sheet.
	2. Rows can be added to reflect labor categories, subcontractors/consultants, and additional ODCs, as necessary. However, none of the fields currently in the template should be removed, to include formulas.
	3. All proposers, to include Universities/Institutions of Higher Education, must include labor hours and associated labor rates for each labor category as stipulated above. Proposers are prohibited from using percent level of effort (LOE) calculations. Proposers are reminded that the resulting awards are Fixed-Price Payable Milestone Other Transactions for Prototype Agreements (meaning, payments are made solely in the amounts found in Attachment 3 of the Agreement).
	4. Cost elements above should be fully burdened, inclusive of all applicable indirect costs. Visibility into indirect rates/costs is not required.
	5. Proposers must provide justification in Volume 2 Price Proposal and any supporting documentation as required.
	6 For PRIME submission - Subcontractor Name: If there are subcontracts, list all subcontractor names.
	7 List Principal Investigator and Key Personnel working on the project even if they receive no salary support.
	8 Subcontracts/Interorganizational Transfers: If appropriate, place Subcontractor name(s) or Interorganizational Name/Code under the Subcontractor section.
	9 Consultants: If appropriate, place Consultant name(s) under the Subcontractor section.
																		Cell Key:
	DARPA Solicitation Number:	Insert DO number																Input
	Proposer:	Proposer's Name (Prime or Sub)																Calculation (DO NO EDIT)
	Prime Contractor	Prime (If Applicable)																No Input
		Milestone 1			Milestone 2			Milestone 3			Milestone 4			Milestone 5			TOTAL PROPOSED HOURS	TOTAL PROPOSED AMOUNT
		Month 3
(see Notes below)			Month 6			Month 9			Month 12			Month 18
	DIRECT LABOR
(List each category separately)	HOURS	RATE	AMOUNT	HOURS	RATE	AMOUNT	HOURS	RATE	AMOUNT	HOURS	RATE	AMOUNT	HOURS	RATE	AMOUNT
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
				$ - 0			$ - 0			$ - 0			$ - 0			$ - 0	- 0	$ - 0
	SUBTOTAL
(all direct labor costs)	- 0		$ - 0	- 0		$ - 0	- 0		$ - 0	- 0		$ - 0	- 0		$ - 0	- 0	$ - 0
	SUBCONTRACTOR(S) & CONSULTANT(S)

(List each separately)

	Subcontract/Interorganizational Name - #01		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
	Subcontract/Interorganizational Name - #02		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
	Subcontract/Interorganizational Name - #03		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
	Insert line(s) for any additional Subcontractors/Interorganizational		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
			$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
	SUBTOTAL
(all subcontractor/consultant costs)		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
	TRAVEL		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
	OTHER DIRECT COSTS
(List each separately)												$ - 0
			$ - 0		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
			$ - 0		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
			$ - 0		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
			$ - 0		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
			$ - 0		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
			$ - 0		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
	SUBTOTAL
(Travel, ODCs)		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
	TOTAL PRICE		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0
	GOVERNMENT SHARE												$ - 0
	RECIPIENT SHARE
(if applicable)		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0		$ - 0

Milestone 1 Total $ - 0 Milestone 2 Total $ - 0 Milestone 3 Total $ - 0 Milestone 4 Total $ - 0 Milestone 5 Total $ - 0

DARPA-PA-21-05

Price Summary Spreadsheet

Version 2, 06/21/2022

Source Selection Information

ScheduleOfMilestonesAndPayments

	SCHEDULE OF MILESTONES AND PAYMENTS
	Milestone #	Milestone	Exit Citeria / Deliverable	Due
Date	Payment	Funded	CLIN
SUBCLIN	ACRN
	1	Experimental Baseline & Validation Protocol	Finalize experimental design; identify intended neural target(s) and predefined nontarget control(s); establish quantitative validation strategy, success criteria, and comparator(s); obtain regulatory approvals as appropriate; complete baseline characterization.	Month 3	$ - 0
	2	Selective Substrate Localization	Complete initial testing and deliver a quantitative dataset and analysis evaluating the localization, confinement, or activation of the intervention within predefined neural substrates relative to appropriate controls.	Month 6	$ - 0
	3	Localized Target Engagement Verification	Perform target engagement assays, deliver the associated dataset analyzing and quantifying biological mechanism activation within targeted substrates using molecular, physiological, imaging, or functional biomarkers. Progress towards the final metrics must be quantifiably demonstrated with statistically significant changes found in target engagement.	Month 9	$ - 0
	4	Circuit-Selective Neuroplasticity Demonstration	Complete comparative evaluations of the neuroplastic response within predefined target substrates relative to nontarget substrates and submit a Preliminary Report along with the comparative experimental dataset.	Month 12	$ - 0
	5	Intervention Prototype Finalization	Deliver the fully integrated, validated intervention prototype (comprising physical hardware, biological constructs, or therapeutic delivery platforms) along with the execution of complete end-to-end intervention prototype validation testing across the full chain of evidence (selectivity, target engagement, and neuroplasticity). Delivery should include 1. The prototype assembly (or certified laboratory configuration specifications), 2. A final prototype technical data package detailing the system’s performance metrics, and 3. An end-to-end validation report demonstrating the prototype’s capability to meet program goals of either A) clinical trial readiness or B) animal testing capability.	Month 18	$ - 0
	Total Agreement				$0.00	$0.00
	*Tasks and targets are aligned with OT Agreement Attachment 1 - Task Description Document
	AUTO POPULATES FROM OTHER TABS -- DO NOT CHANGE FORMULAS OR IN THIS SPREADSHEET

Attachment 3 - Schedule of Milestones and Payments

File details come from the government source that posted it. Updated Sep 3, 2026.