Attachment 1 - Statement of Needs - High Through-Put Liquid Handling_Final.pdf
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- Solicitation number
- RFQ-NIAID-23-2159463-1
About this file
This Statement of Needs outlines requirements for two high throughput liquid handling systems for protein crystal production. The systems must use positive displacement liquid dispensers with a minimum of six dispensing syringes for non-contact aspensing of nanoliter sample volumes. Equipment must implement a zero cross-contamination system using disposable pipettes and be capable of handling a wide range of liquids from 80% ethanol to 50% glycerol without liquid classification. Common assay components, buffers, DMSO, beads, cells, and glycerol stocks must be dispensed under standard settings along with particulates like SPRI beads. The systems must include a fixed base configuration to share protocols and feature a microplate shaker and incubation capabilities. Off-the-shelf protocols for immediate use are required.
The related federal contract opportunity is a solicitation issued by the National Institute of Allergy and Infectious Diseases within the Department of Health and Human Services seeking high throughput liquid handling systems by brand name or equal.
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Other files
| File | Type | Posted |
|---|---|---|
| Attachment 2- Bill of Materials (BOM).xlsx | XLSX spreadsheet | |
| Attachment 3 - Full Text Clauses.pdf |
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Statement of Needs (SON) – High Through-Put Liquid Handling Systems
This SON is for the procurement of two instruments for the production of protein crystals for structure determination capable of the following:
The High Through-Put Liquid Handling Systems use liquid dispensers with positive displacement of liquids for aspiration and non-contact dispensing with a minimum of 6 dispensing syringes.
These systems dispense nanoliter amounts of material, making optima use of precious and difficult to produce samples. Plastic consumable tips are automatically exchanged to minimize cross contamination of the samples.
The two minimal specifications for each system are as follows:
The Liquid Handling System: This Dispensing system must use liquid dispensers with positive displacement of liquids for aspiration and non-contact dispensing with a minimum of 6 dispensing syringes. Equipment must have a zero cross contamination system that allows for the use of disposable pipettes.
Liquid Class Management System: This system is necessary to produce the crystal growth conditions. The dispense system must be capable of handling a wide range liquid type from 80% ethanol through to 50% (w/v) glycerol, with NO requirement for liquid classification. Common biological assay components such as aqueous buffers, DMSO, beads, cells, or glycerol protein stocks must all be dispensed using the same standard settings as well as particulates such as SPRI beads. Use of a positive displacement system is needed. The system must include fixed base configurations to share protocols between the two high-through put liquid handling systems.
Configuration must also include a microplate shaker and incubation capabilities.
Both systems must be application ready with off the shelf protocols ready to use.
File details come from the government source that posted it. Updated .