2-Synopsis-Intent to sole source for BD Biosciences CYTOMETER FINAL.pdf

Synopsis No. 75N96023Q00046

NIEHS, Office of Acquisitions

FACSymphony S6 Flow Cytometer System

Synopsis

SYNOPSIS

General Information

Document Type: Synopsis Synopsis Number: 75N96023Q00046 Posted Date: May 22, 2023 Original Response Date: May 30, 2023 Current Response Date: May 30, 2023 Set Aside: N/A NAICS Code: 334516 - Analytical Laboratory Instrument

Manufacturing

Contracting Office Address

NIEHS

530 Davis Drive Durham, NC 27709

Description

THIS IS A NOTICE OF INTENT AND NOT A REQUEST FOR QUOTATIONS.

The National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC intends to negotiate on a sole source basis with Becton, Dickinson & Company, BD Biosciences Unit, 1 Becton Drive, Franklin Lakes, NJ 07417, UEI: JJFKLGY7TBJ5.

This acquisition is conducted under the authority of 41 U.S.C. § 1901 – Simplified acquisition procedures, as implemented by FAR section 13.501, in accordance with (IAW) FAR 6.302-1 Only one responsible source and no other supplies or services will satisfy agency requirements.

This purchase is for: BD FACSymphony S6 flow cytometer

BD Biosciences is the only vendor that can provide the FACSymphony S6 an instrument with the capabilities required by NIEHS scientist. The Flow Cytometry Center (FCC) at NIEHS requests the purchase of a BD FACSymphony S6 flow cytometer to replace our current 13-year-old FACSAriaII flow cytometer located in the Flow Cytometry Center at NIEHS. As the current FACSAriall serves as both a cell sorter and a cell analyzer, it is critical that the requested instrument will also need to function in both capacities. The requested flow cytometer needs to have at a minimum 48 versatile parameters equipped with at least 5 fixed-aligned, air-cooled lasers, including a 355 nm, 405 nm, 488 nm, 561 nm, and 637 nm laser lines. Additionally, the instrument needs to have the capability of detecting 10 parameters from the 355 laser, 14 parameters from the 405 nm laser, 9 parameters from the 488 nm laser, 9 parameters from the 561 nm laser and 6 parameters from the 637 nm laser. The instrument needs to be equipped with a cuvette-based gel-coupled flow cell that allows enhanced resolution and sensitivity. The instrument needs to be capable of simultaneously sorting 6 unique cell populations into assorted collection vessels including numerous tubes and multi-well plates that are temperature controlled. The instrument must have an intuitive user interface that with on screen instructions allowing easy operation of the instrument for alignment and aseptic-sort tasks. The instrument must have the capability to handle panels and acquisition protocols from our current instruments including the ability to integrate and facilitate the utilization of FlowJo analysis software. Furthermore, the system needs have an independent aerosol management (AMS) system to provide both personnel product protection. Finally, the system needs to be compatible with our existing instruments. The BD FACSymphony S6 flow cytometer offers these unique qualifications to meet the needs of NIEHS scientists. Since the FACSDiVa platform that operates the BD FACSymphony S6 Cell Sorter with the FlowJo analysis software used by many NIEHS investigators to setup and/or analyze their studies is identical to what is currently being used in the FCC, this compatibility with our current equipment allows for existing acquisition software panels and templates, acquisition SOPs, and data analysis pipelines will be directly transferable.

In summary, because the FACSymphony S6 flow cytometric system has specific features not available from other manufacturers thus enabling this instrument to meet the sorting needs of NIEHS investigators, BD Biosciences is the only uniquely qualified vendor capable to meet the Government’s requirement.

Period of Performance/Delivery: NLT 9/30/2023

This notice of intent is not a solicitation or request for quotes. Notwithstanding, any responsible source that believes it is capable of meeting NIEHS requirement, may submit capability statement. Responses to this posting must be submitted via email to Chantal.cornelius@nih.gov, by May 30. 2023, at 9:00 AM EST.

Interested Parties in assisting NIEHS with this market research are requested to submit the following information in the format of a White Paper outlined below. The response should be concise (no more than 20 pages), 11 pt Calibri font, and address only the information requested below. Bulleted lists and summaries are acceptable. (Note: title pages, cover letters, etc., will not count against the total page limit).

Generic capability statements will not be provided to the requirements team for review.

Interested Parties shall provide the following information:

I. COMPANY INFORMATION

a. Company Name

b. CAGE Code

c. Point of Contract Name, Phone Number, and E-mail Address

d. Company Website

e. ALL government contract vehicles under which the Company holds contracts (e.g., GSA Federal Supply Schedule (FSS), NITAAC, OASIS, etc.)

II. BUSINESS SIZE

a. The anticipated NAICS for this effort is 334516 Analytical Laboratory Instrument

Manufacturing. The Small Business Administration (SBA) small business size standard for this NAICS code is 1000 employees.

b. Based on the NAICS 334516, identify your business size as Small or Large.

c. If a small business concern, identify which, if any, of the below small business socio-economic categories are applicable:

Small Disadvantaged Business (SDB

Woman-Owned Small Business (WOSB)

Economically Disadvantaged Woman-Owned Small Business

(EDWOSB)

Veteran-Owned Small Business (VOSB)

Service-Disabled Veteran-Owned Small Business (SDVOSB)

HUBZone Small Business (HZ)

d. If your company is an Other Than Small Business (OTSB) concern (i.e., large business), have you partnered or subcontracted with small business concerns to provide the same or similar services as this requirement?

III. CAPABILITIES

a. Generally, describe your company’s capabilities in fulfilling the specifications included above.

b. Specifically, address the information in subparagraphs i. through iii below:

i. Concisely describe your company’s ability to provide the requested specifications. Include supporting information which demonstrates your company’s knowledge / capability to meet the specifications.

If your company does not have direct experience, please explain how you would meet the specifications utilizing experienced subcontractors, through a proposed contract teaming arrangement (CTA) or hiring qualified personnel.

ii. Has your company performed work of the same or similar scope as this requirement within the last three (3) years? Please explain.

For any contracts or projects for the same or similar work performed by your company within the last three (3) years, please provide the following information relating (no more than three (3) examples; government or commercial contracts):

• Brief Description of the Contract/Project

• Contract Number

• Period of Performance

• Contract Type(s) (e.g., FFP, T&M, Labor-Hour (LH), etc.)

• Commercial or Non-Commercial Requirement?

• Was your company a prime or subcontractor?

• Contract/Project Dollar Value

• Scope of the portion of the effort your company supported

iii. Provide additional relevant experience/ information that demonstrate your company’s capabilities.

A determination by the Government not to compete this contract action based upon responses to this notice is solely with the discretion of the Government. Information received will only be considered for the purpose of determining whether to conduct a competitive procurement.

There is no solicitation package available. For any questions regarding this announcement, please contact Mrs. Chantal Rosales Cornelius at the above email address.