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NIH Clinical Center

Critical Care Medicine Department CCMD research section Statement of Work

BACKGROUND INFORMATION

The Critical Care Medicine Department (CCMD) was established in November 1977 to provide medical care for critically ill patients throughout the Clinical Center who have potentially reversible medical problems. Critical care medicine may be defined as the observation, diagnosis, treatment, and rehabilitation of patients with overt or potential failure of vital functions.

The Department is currently composed of the following sections:

· Clinical Medical Services

· Critical Care Therapy and Respiratory Care

· Research Section

· AIDS Section

· Administrative Services

CCMD Mission

To provide high quality and cost effective clinical service that meets the needs of CC patients and NIH Institutes, to facilitate the research goals of NIH Institutes and investigators, and to conduct high quality research and training in Critical Care Medicine.

CCMD Research Section The Critical Care Medicine Department conducts active research programs in bedside clinical investigation, research in animal models, and molecular biology.

Full-time research activities commence at the beginning of the second year of the fellowship for fellows interested in the critical care subspecialty alone. For those interested in dual board eligibility, their second-year program is individually designed and consists of clinical rotations required for board eligibility in the particular subspecialties. After completion of second subspecialty training, full-time research activities commence. Major topics of research interest within the Department include:

· The immunopathogenesis of septic shock

· Studies of immune cellular function in respiratory distress syndrome, asthma, and other forms of severe pulmonary disease

· Biomarkers and novel therapies in pulmonary arterial hypertension

· Biomarkers of acute cellular rejection in heart transplantation

· Diagnosis and treatment of opportunistic infections

· Studies of immune cellular function and therapy of AIDS

· Pathogenesis and treatment of anthrax

· Emerging infectious diseases

· Biology and clinical effects of nitric oxide

· acute lung injury

· pulmonary arterial hypertension

· role as transcription regulatory factor

· Functional genomics of critical illness

· human acute inflammation

· animal model of septic shock and multiple organ failure

· pulmonary arterial hypertension

· solid organ transplantation

· Emerging Infectious Disease

PURPOSE

The purpose of this correspondence is to request a PO for a services contract on the TECAN INSTRUMENT POWER SCANNER system (Serial Number: 1509006864/ instrument # 11234356 currently under warranty) that performs translational research evaluating the pathogenesis and treatment of high-consequence respiratory viral pathogens, inflammation, pulmonary hypertension, and samples from our emergent diseases research.

The Service Contract Agreement includes

1. Scheduled one preventive maintenance visit per year including:

· Cleaning and greasing

· Wear & tear parts (these typically include, but are not limited to, valves, syringes, tips, tip assemblies, and tubing)

· Adjustments

· Instrument specific tests as outlined in the Service Manual

· Service Report

· Travel costs and labor

2. On-site repairs in case of instrument failure including:

· Spare parts (as required)

· Travel costs and labor

· Service Report

3. Update installations at the time of scheduled preventive maintenance visits (released for use on the instrument and at the discretion of Tecan are required to be installed on the instrument to maintain reliability, usability and/or safety; upgrades are not included in the coverage of this contract):

· Essential Hardware updates

· Essential Firmware updates

· Essential Software updates

4. Other included services:

· Hotline support (Mo-Fr between 08:00 am and 05:00 pm “local time”, excluding statutory holidays)

· Services performed by Tecan certified field service engineers or application specialists

· General response time 48 hours

PERIOD OF PERFORMANCE

11/12/2018 through 11/12/2019.

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