NAICS Code 325411: Medicinal and Botanical Manufacturing
National industry
SBA small business size standard: 1,000 employees
Definition
This U.S. industry comprises establishments primarily engaged in (1) manufacturing uncompounded medicinal chemicals and their derivatives (i.e., generally for use by pharmaceutical preparation manufacturers) and/or (2) grading, grinding, and milling uncompounded botanicals.
Government contracts for this product: PSC 6505 Drugs and Biologicals
Code facts
- Part of
-
-
31-33
-
325
-
3254
- 32541
-
3254
-
325
-
31-33
- Contract awards
- 108,638 In the last 12 months
- Contract obligations
- $4,925,547,215 In FY2025
NAICS codes and definitions come from the U.S. Census Bureau, size standards from the SBA and contract spending from SAM.gov/FPDS.
Business activities under NAICS 325411
- Acetylsalicylic acid manufacturing
- Adrenal derivatives, uncompounded, manufacturing
- Agar-agar grinding manufacturing
- Amphetamines, uncompounded, manufacturing
- Anesthetics, uncompounded, manufacturing
- Antibiotics, uncompounded, manufacturing
- Anticholinergics, uncompounded, manufacturing
- Anticonvulsants, uncompounded, manufacturing
- Antidepressants, uncompounded, manufacturing
- Ascorbic acid (i.e., vitamin C), uncompounded, manufacturing
- Atropine and derivatives manufacturing
- Barbiturates, uncompounded, manufacturing
- Barbituric acid manufacturing
- Brucine manufacturing
- Caffeine and derivatives (i.e., basic chemicals) manufacturing
- Cephalosporin, uncompounded, manufacturing
- Cinchona and derivatives (i.e., basic chemicals) manufacturing
- Cocaine and derivatives (i.e., basic chemicals) manufacturing
- Cod liver oil, medicinal, uncompounded, manufacturing
- Codeine and derivatives (i.e., basic chemicals) manufacturing
- Concentrated medicinal chemicals, uncompounded, manufacturing
- Cortisone, uncompounded, manufacturing
- Digitoxin, uncompounded, manufacturing
- Endocrine products, uncompounded, manufacturing
- Enzyme proteins (i.e., basic synthetic chemicals), pharmaceutical use, manufacturing
- Ephedrine and derivatives (i.e., basic chemicals) manufacturing
- Ergot alkaloids (i.e., basic chemicals) manufacturing
- Fish liver oils, medicinal, uncompounded, manufacturing
- Glandular derivatives, uncompounded, manufacturing
- Glycosides, uncompounded, manufacturing
- Grinding and milling botanicals (i.e., for medicinal use)
- Herbal supplements manufacturing
- Hormones and derivatives, uncompounded, manufacturing
- Hypnotic drugs, uncompounded, manufacturing
- Insulin, uncompounded, manufacturing
- Magnesia, medicinal, uncompounded, manufacturing
- Medicinal chemicals, uncompounded, manufacturing
- Morphine and derivatives (i.e., basic chemicals) manufacturing
- Nicotine and derivatives (i.e., basic chemicals) manufacturing
- N-methylpiperazine manufacturing
- Oils, vegetable and animal, medicinal, uncompounded, manufacturing
- Ophthalmic agents, uncompounded, manufacturing
- Opium and opium derivatives (i.e., basic chemicals) manufacturing
- Penicillin, uncompounded, manufacturing
- Physostigmine and derivatives (i.e., basic chemicals) manufacturing
- Pituitary gland derivatives, uncompounded, manufacturing
- Procaine and derivatives (i.e., basic chemicals) manufacturing
- Quinine and derivatives (i.e., basic chemicals) manufacturing
- Reserpines (i.e., basic chemicals) manufacturing
- Salicylic acid, medicinal, uncompounded, manufacturing
- Steroids, uncompounded, manufacturing
- Strychnine and derivatives (i.e., basic chemicals) manufacturing
- Sulfa drugs, uncompounded, manufacturing
- Sulfonamides, uncompounded, manufacturing
- Tetracycline, uncompounded, manufacturing
- Theobromine and derivatives (i.e., basic chemicals) manufacturing
- Vegetable alkaloids (i.e., basic chemicals) (e.g., caffeine, codeine, morphine, nicotine), manufacturing
- Vitamins, uncompounded, manufacturing
Show all 58
Looking for another activity? Search the NAICS code lookup or browse business activities from A to Z.
Contract obligations by fiscal year
| Fiscal year | Obligated |
|---|---|
| FY2027 To date | -$2,922 |
| FY2026 | $4,513,415,682 |
| FY2025 | $4,925,547,215 |
| FY2024 | $4,192,027,527 |
| FY2023 | $3,276,101,568 |
Top contractors by obligations
| Rank | Contractor | Obligated, FY2026–FY2027 | Share |
|---|---|---|---|
| 1 | Amerisourcebergen Drug Corp | $4,451,848,911 | |
| 2 | Emergent Biodefense Operations Lansing LLC | $21,534,000 | |
| 3 | DMS Pharmaceutical Group Inc. | $13,889,075 | |
| 4 | Cardinal Health, Inc. | $4,820,205 | |
| 5 | Animal Health International, Inc. | $4,658,434 | |
| 6 | Atlantic Diving Supply, Inc. | $2,738,327 | |
| 7 | Altitude Technologies Inc. | $1,915,507 | |
| 8 | Serb Medical Solutions Inc. | $1,752,310 | |
| 9 | Fresenius Kabi, LLC | $1,632,982 | |
| 10 | Phoenix Textile Corporation | $1,031,123 |
See the full FY2025 ranking of NAICS 325411 contractors, by parent company.
Top funding agencies by obligations
| Rank | Agency | Obligated, FY2026–FY2027 | Share |
|---|---|---|---|
| 1 | Defense Logistics Agency | $4,483,867,518 | |
| 2 | Department of the Army | $21,534,000 | |
| 3 | Department of the Interior | $4,658,434 | |
| 4 | Department of State | $1,844,231 | |
| 5 | Department of Health and Human Services | $1,095,263 | |
| 6 | Defense Health Agency | $230,419 | |
| 7 | Air Force | $85,088 | |
| 8 | Department of Veterans Affairs | $59,179 | |
| 9 | Department of Justice | $25,388 | |
| 10 | Department of Agriculture | $13,240 |
Top PSC codes by obligations
| Rank | PSC code | Obligated, FY2026–FY2027 | Share |
|---|---|---|---|
| 1 | 6505 Drugs and Biologicals | $4,425,964,708 | |
| 2 | 6515 Medical and Surgical Instruments, Equipment, and Supplies | $81,556,638 | |
| 3 | 6509 Drugs and Biologicals, Veterinary Use | $4,658,434 | |
| 4 | AN11 Health R&D Services; Health Care Services; Basic Research | $1,095,953 | |
| 5 | 6510 Surgical Dressing Materials | $49,783 | |
| 6 | 6532 Hospital and Surgical Clothing and Related Special Purpose Items | $31,886 | |
| 7 | 7210 Household Furnishings | $22,078 | |
| 8 | 6810 Chemicals | $16,954 | |
| 9 | 2541 Weapons Systems Specific Vehicular Accessories | $14,700 | |
| 10 | 6530 Hospital Furniture, Equipment, Utensils, and Supplies | $1,003 |
Contract obligations by state
| Rank | Place of performance | Obligated, last 12 months | Share |
|---|---|---|---|
| 1 | Pennsylvania | $4,010,060,254 | |
| 2 | Michigan | $21,534,000 | |
| 3 | Illinois | $16,275,067 | |
| 4 | Ohio | $5,019,324 | |
| 5 | District of Columbia | $2,999,997 | |
| 6 | Virginia | $1,987,450 | |
| 7 | Oklahoma | $1,843,627 | |
| 8 | Arizona | $1,731,587 | |
| 9 | Missouri | $1,304,565 | |
| 10 | New York | $1,150,097 | |
| 11 | California | $1,033,781 | |
| 12 | Georgia | $700,629 | |
| 13 | Texas | $653,422 | |
| 14 | New Jersey | $638,507 | |
| 15 | North Carolina | $377,806 | |
| 16 | Wisconsin | $136,432 | |
| 17 | Delaware | $110,020 | |
| 18 | Tennessee | $105,099 | |
| 19 | Massachusetts | $42,562 | |
| 20 | Kentucky | $17,508 | |
| 21 | Florida | $6,860 | |
| 22 | South Carolina | $920 |
Show all 22
Contract opportunities
Show 36 more
Latest 46 of 550 listed here. See the rest on GovTribe.
Size standard history
Federal Register rules that named this code
From the NAICS codes each rule's amendments to 13 CFR 121.201 name. Rules that print their size standard tables as images aren't listed.
Quick answers
What is NAICS 325411?
NAICS 325411 is Medicinal and Botanical Manufacturing, a national industry in NAICS 31-33, Manufacturing.
What is the NAICS code for brucine manufacturing?
The NAICS code for brucine manufacturing is 325411, Medicinal and Botanical Manufacturing.
What is the NAICS code for barbituric acid manufacturing?
The NAICS code for barbituric acid manufacturing is 325411, Medicinal and Botanical Manufacturing.
What is the NAICS code for agar-agar grinding manufacturing?
The NAICS code for agar-agar grinding manufacturing is 325411, Medicinal and Botanical Manufacturing.
When did the size standard for NAICS 325411 last change?
The most recent Federal Register rule on record that names NAICS 325411 in the SBA's size standards is "Small Business Size Standards for Manufacturing" (81 FR 4469), published Jan 26, 2016 and effective Feb 26, 2016.
How much do federal agencies spend under NAICS 325411?
Federal contracts under NAICS 325411 obligated $4,925,547,215 in fiscal year 2025 and $16,907,089,069 in fiscal years 2023 through 2027.
Who are the largest contractors under NAICS 325411?
The contractors with the most obligated under NAICS 325411 in fiscal years 2026 and 2027 are Amerisourcebergen Drug Corp ($4,451,848,911), Emergent Biodefense Operations Lansing LLC ($21,534,000) and DMS Pharmaceutical Group Inc. ($13,889,075).
Which agencies buy the most under NAICS 325411?
The agencies that obligated the most under NAICS 325411 in fiscal years 2026 and 2027 are Defense Logistics Agency ($4,483,867,518), Department of the Army ($21,534,000) and Department of the Interior ($4,658,434).
Which PSC codes are used with NAICS 325411?
The PSC codes with the most obligated under NAICS 325411 in fiscal years 2026 and 2027 are 6505 Drugs and Biologicals; 6515 Medical and Surgical Instruments, Equipment, and Supplies; and 6509 Drugs and Biologicals, Veterinary Use.
Where is the work under NAICS 325411 performed?
By place of performance, the states with the most contract obligations under NAICS 325411 over the last 12 months are Pennsylvania ($4,010,060,254), Michigan ($21,534,000) and Illinois ($16,275,067).
What is the latest contract opportunity under NAICS 325411?
The latest contract opportunity under NAICS 325411 is Pharm Manuf/
On GovTribe
See everything under NAICS 325411
- Federal contract opportunities, awards and IDVs under this code
- Funding analysis by contractor, agency and set-aside
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