ABRC, ISA - CPAE Registry & Biospecimen Repository

The Arizona Department of Health Services (ADHS) has established a Master Agreement (CTR065451) with the University of Arizona to develop and maintain a specialized Childhood Postinfectious Autoimmune Encephalopathy (CPAE) Patient Registry and Biospecimen Repository. This Indefinite Delivery Vehicle (IDV) focuses on creating a comprehensive research platform for pediatric neuropsychiatric conditions, specifically PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) and PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections). The master agreement enables the University to develop a web-based research registry using REDCap software, establish a biorepository for collecting and cataloging biospecimens, conduct behavioral intervention research, and provide professional education through annual training workshops.

The prime contractor for this IDV is the University of Arizona, with the contract administered by the Arizona Department of Health Services. The master agreement is effective from September 14, 2023, to September 13, 2028, covering the state of Arizona. The total contract value is $1,790,000, with annual funding ranging from $250,000 to $465,000 across the five-year performance period. The contract is structured as an Interagency Service Agreement (ISA) and is funded through the Arizona Biomedical Research Centre (ABRC) using Arizona Tobacco Tax Fund appropriations. Key deliverables include quarterly program progress reports, quarterly expenditure reports, and the establishment of a fully functional CPAE Patient Registry and Biorepository by the contract's conclusion.