Project Grant T32HL182705
- The National Institutes of Health National Heart Lung and Blood Institute awarded Ann & Robert H Lurie Children's Hospital of Chicago $876,614 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to conduct a multisite prospective cohort study advancing acute respiratory infection treatment in pediatric invasive home mechanical ventilation. The research will enroll 400 children in English and Spanish language families using long-term home mechanical...
- The National Institutes of Health National Heart Lung and Blood Institute awarded Ann & Robert H Lurie Children's Hospital of Chicago $781,860 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate the novel role of neutrophils in mediating endothelial regeneration and vascular repair in sepsis and acute respiratory distress syndrome (ARDS). The research addresses ARDS pathology, specifically endothelial barrier injury and increased vascular...
- The National Heart, Lung, and Blood Institute awarded Ann & Robert H Lurie Children's Hospital of Chicago $778,202 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to fund research targeting inflammaging-induced endothelial injury and acute respiratory distress syndrome (ARDS) development in aging lungs. The research investigates how aging influences endothelial barrier injury mechanisms in ARDS, with focus on endothelial NADPH oxidase 2 (NOX2)...
- The National Heart, Lung, and Blood Institute awarded Ann & Robert H Lurie Children's Hospital of Chicago $509,622 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to evaluate novel ultrasound techniques for assessing right ventricular diastolic dysfunction in children with pulmonary arterial hypertension. The project conducts a prospective two-center observational cohort study combining conventional ultrasound and ultrafast ultrasound (UFUS) imaging...
- The National Heart, Lung, and Blood Institute awarded Children's Research Institute $1,818,088 on July 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate how postnatal hypoxemia—reduced blood oxygen levels present in cyanotic congenital heart disease—impacts cardiac maturation and surgical recovery outcomes in pediatric patients. The project will examine the interaction between hypoxemia, myocardial immaturity, and postoperative complications through...
- The National Heart, Lung, and Blood Institute awarded The University of Chicago $817,976 on August 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop single molecule footprinting methods for studying gene regulation in cardiac differentiation and disease. The recipient will combine methyltransferase-based chromatin measurement with native long-read sequencing to assess chromatin accessibility, nucleosome positioning, transcription factor binding, and DNA...
- The National Heart, Lung, and Blood Institute awarded Seattle Children's Hospital $930,637 under the Cardiovascular Diseases Research program (CFDA 93.837) on September 1, 2026, to conduct PROSPER (Pulmonary Recovery and Outcomes After Severe Pediatric Respiratory Illness), a multicenter prospective longitudinal cohort study examining how impaired pulmonary function contributes to physical and health-related quality-of-life morbidity among children surviving acute respiratory failure. The...
- The National Heart, Lung, and Blood Institute awarded Children's Research Institute $126,518 on August 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to build a patient-oriented research mentoring program in human neonatal and infant airway biology. The award funds mentoring and research addressing mechanisms regulating airway epithelial immune responses in early life, with particular focus on populations historically excluded from respiratory research: infants with...
- The National Institutes of Health National Heart, Lung, and Blood Institute awarded The Children's Hospital of Philadelphia $1,741,543 on September 15, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate lung injury in pediatric hematopoietic cell transplant recipients. The research examines molecular mechanisms of pulmonary toxicity in pediatric HCT recipients, who experience lung injury in up to 40% of cases with mortality rates of 40% when requiring...
- The National Heart, Lung, and Blood Institute awarded The Children's Hospital of Philadelphia $115,584 on July 3, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to support computational and experimental investigations of deformation-driven molecular pathways in single right ventricle congenital heart disease. The project, a K25 career development award, will fund research into tricuspid valve regurgitation in pediatric patients with single right ventricle congenital heart...
The National Heart, Lung, and Blood Institute awarded Ann & Robert H Lurie Children's Hospital of Chicago $438,328 on August 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to support the Pediatric Acute Care Research (PACER) Training Program. The PACER program provides postdoctoral scholars with mentored, experiential research opportunities, didactics, seminars, apprenticeships, and career development experiences in pediatric emergency and critical care medicine. The curriculum addresses the shortage of acute care pediatrician-scientists and research training opportunities by de-siloing emergency and critical care trainees under a single multidisciplinary umbrella rather than distinct specialty programs. The program focuses on respiratory conditions, acute cardiovascular dysfunction, and resuscitation—the chief pathways to morbidity and mortality in children and key focus areas for NHLBI. Three program aims are to recruit and train collaborative scholars to design and conduct rigorous, high-impact pediatric acute care research; ensure trainees attain scientific expertise, professional skills, and career readiness through mentored experiences; and establish a sustainable research training infrastructure. The award funds work performed in Chicago, Illinois, with a period of performance from August 1, 2026, through July 31, 2031. This is a Project Grant, classified as an assistance award.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $12.8k | 8/28/26 | ||
| Not listed | $212.8k | 8/10/26 |