Project Grant T32GM165287
- The National Institute of General Medical Sciences awarded the University of Massachusetts Medical School $360,125 on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop new luciferin substrates that extend bioluminescent emission into the near infrared spectrum and corresponding luciferases that efficiently utilize these substrates. The project addresses limitations in current bioluminescence assays and imaging methods by engineering luciferins...
- The National Institute of General Medical Sciences awarded the University of Massachusetts $2.35 million on August 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to investigate non-specific electrostatic interactions of biological macromolecules in physiological and pathological processes. The project examines how highly charged polycationic and polyanionic biomacromolecules — including heparin, neutrophil extracellular traps, and other polymeric species —...
- The National Institute of General Medical Sciences (NIGMS) awarded a Project Grant totaling $457,500.00 under the Biomedical Research and Research Training Program (CFDA 93.859) to the University of Massachusetts Boston. The grant, with a performance period from September 17, 2024 to August 31, 2027, aims to systematically identify chemical processes and reactions that show promise when initiated under high hydrostatic pressure (HHP) conditions. The research will involve a combination of...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) provides $455,940 to the University of Massachusetts Lowell to study the biophysical properties of intrinsically disordered proteins (IDPs) when confined to nanoscale environments. The research aims to reveal how the structural plasticity of IDPs is influenced by their localization and confinement on nanoparticle constructs, with the...
- The National Institute of General Medical Sciences awarded the University of Massachusetts Boston $431,330 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to establish U-RISE, a research training initiative designed to broaden participation in biomedical PhD programs among underserved undergraduate students. U-RISE will enroll 18 students annually for two-year appointments, targeting underrepresented minorities, students from disadvantaged...
- The National Institute of General Medical Sciences awarded Massachusetts Institute of Technology $269,071 on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop and apply cryo-electron microscopy and cryo-electron tomography methods for visualizing protein machine assembly, function, and regulation at high resolution. The work emphasizes development of the CryoDRGN and TomoDRGN software ecosystem to enable structural analysis of complex samples in...
- The National Institute of General Medical Sciences awarded The Broad Institute, Inc. $1,079,960 on September 10, 2025, under the Biomedical Research and Research Training program (CFDA 93.859) to expand MicroTutor, an online platform for training biologists in quantitative bioimaging and bioimage analysis. MicroTutor delivers microscopy and bioimage analysis education through interactive learning technologies, combining short video lessons with interactive demonstrations and frequent mastery...
- Federal Grant Award Summary The University of Massachusetts Medical School received a $460,625 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) beginning September 1, 2025 and concluding August 31, 2030. This award supports research on causal inference methodologies for reconstructing gene regulatory networks (GRNs) at the single-cell level. The project will develop advanced computational...
- Federal Grant Award Summary The University of Massachusetts received a $396,854 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2029. The award supports the development of a nanopore tweezer toolkit designed to analyze kinase structural dynamics and screen allosteric inhibitors. This research leverages protein nanopore sensor technology to...
- The National Institute of General Medical Sciences awarded $502,372 to Massachusetts Institute of Technology on July 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop selective, catalytic isomerization reactions that convert simple organic building blocks into complex organic molecules relevant to biomedical research. The work encompasses stereocenter editing—precise interconversion of stereoisomeric molecules at late synthetic stages to enable...
The National Institute of General Medical Sciences (NIGMS), part of the Department of Health and Human Services National Institutes of Health, awarded the University of Massachusetts Lowell $431,337 on August 20, 2026, for the BRITE (Biotechnology Research, Innovation, Training, and Education) Predoctoral Training Program under CFDA 93.859 (Biomedical Research and Research Training). The BRITE program delivers predoctoral training in biotechnology and biomedical sciences to eight students per year through mentorship by 22 faculty members across nine departments spanning the Colleges of Engineering, Sciences, and Health Sciences. Training covers five thematic areas: medical imaging, optical sensing and biomedical optics; biomaterials, tissue engineering, and regenerative medicine; materials, polymers, nanomaterials, and surface chemistry; biomanufacturing and metabolic and process engineering; and life sciences, pathogens, immunology, and computational biology. The program recruits from undergraduate and master's students affiliated with participating faculty research groups and coordinates experiential learning opportunities with life sciences industry partners in the Merrimack Valley and Greater Boston region. Work is performed in Lowell, Massachusetts, with a period of performance extending through June 30, 2031. The award is structured as a project grant, the standard assistance type for this NIGMS program.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $0 | 8/21/26 | ||
| Not listed | $431.3k | 8/19/26 |