Project Grant T32AI179604
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $637,729 to President and Fellows of Harvard College (doing business as Harvard Medical School) from December 13, 2024 to November 30, 2029. The funding supports research to investigate the molecular mechanisms underlying the activation and regulation of essential bacterial cell wall synthase enzymes, with...
- This Project Grant award of $111,513.00 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research on the molecular basis of cyclic-di-AMP regulation in Gram-positive bacteria. The central hypothesis is that Gram-positive bacteria use the protein CDAR to sense changes in the cell envelope and adjust levels of the second messenger cyclic-di-AMP to facilitate envelope repair. The project aims...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $749,417 to President and Fellows of Harvard College to develop novel antibiotic candidates that target the lipoprotein transport pathway in Gram-negative bacteria. The research aims to synthesize and evaluate a modular platform of antibiotics with improved potency and optimized...
- This Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) is funding research at Harvard Medical School to investigate the assembly pathway of mycomembrane proteins in bacterial cell envelopes. The $125,901 award, with a project period from Sep 3, 2025 to Aug 31, 2027, aims to characterize the role of mycoloyltransferase enzymes in transporting and assembling outer membrane proteins critical for bacterial cell...
- This $193,375 Project Grant, awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to identify bacterial determinants that may contribute to variable treatment responses for tuberculosis (TB). The project, conducted by researchers at the Harvard T.H. Chan School of Public Health, aims to investigate the effects of clinically prevalent variants in the ESX1 secretion system on TB...
- This Project Grant award of $1,451,970.00 from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports research on evolutionary tradeoffs in antibiotic resistance at Harvard Medical School. The research aims to explore factors in the environment that may have a countervailing effect on the evolution of antibiotic resistance, including studies on the direct and indirect evolutionary costs of resistance, the...
- This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $2,494,866.00 to President and Fellows of Harvard College, doing business as Harvard Medical School, to conduct research to characterize innate immune signaling pathways in the tick Ixodes scapularis. The research aims to improve understanding of immune signaling in ticks, which are vectors of Lyme disease...
- This federal Project Grant award of $453,750 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research grant program (CFDA 93.855). The grant is funding research at Tufts University School of Medicine to study how bacteriophages (viruses that attack bacteria) evade the protective antiviral systems present in bacteria, including deadly pathogens like Vibrio cholerae. Specifically, the researchers will determine the...
- This Project Grant awarded by the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to investigate a novel phospholipase, PLPD, that may play a role in maintaining the outer membrane permeability barrier in the human pathogen Pseudomonas aeruginosa. The $137,286 award to President and Fellows of Harvard College, operating as Harvard Medical School, will fund experiments to determine if PLPD...
- This federal Project Grant award of $167,915 was provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports research by Harvard Medical School to define how B cell receptor binding site copy number at the cell surface is developmentally regulated to optimize antigen recognition and support affinity-driven antibody selection. Key objectives include: 1) Determining the molecular...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research (CFDA 93.855) program, provides $325,806 to support a Bacteriology PhD Training Program at Harvard Medical School. The program aims to train 8 second- and third-year graduate students in the Harvard Graduate Program in Bacteriology (GPIB), teaching them to identify important research questions and develop the technical and intellectual skills to address them. The program focuses on fundamental mechanisms of bacterial cell biology, host-pathogen interactions, and the roles of bacteriology in science and society. It provides coursework, seminars, and professional development activities to cultivate critical thinking, experimental design, and communication skills in the trainees. This award, with a performance period from September 2025 to August 2030, supports the vibrant research community and infrastructure at Harvard Medical School to deliver this comprehensive bacteriology training program.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $325.8k | 9/19/25 |