Project Grant S10OD040202
- The University of Utah received a $1,790,631 project grant from the National Institutes of Health Office of the Director under the Research Infrastructure Programs federal grant program (CFDA 93.351) to acquire an X-ray diffraction system. The system, a Rigaku XtaLAB Synergy-DW single crystal X-ray diffractometer, will replace aging instrumentation in the university's biochemistry and chemistry departments that is no longer supported by the vendor and experiencing maintenance challenges. It will...
- Federal Grant Award Summary The University of Nebraska received a $340,920 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective July 1, 2025 through June 30, 2030. This award supports the development and integration of advanced mass spectrometry technologies for characterizing ribosomal heterogeneity and macromolecular assembly. The research will yield novel top-down proteomics and...
- The University of North Carolina at Chapel Hill received a $2.0 million Project Grant from the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) to acquire a JEOL JEM-CRYO ARM300 (JEM-3300), a 300 kilovolt (kev) cryogenic-transmission electron microscope (cryoTEM). The award, obligated on August 1, 2025, with a completion date of July 31, 2026, will establish this instrument at UNC-CH's cryoEM Core facility to support high-resolution...
- Federal Grant Award Summary The University of Nebraska Board of Regents received a $2.04 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), awarded August 8, 2025, with completion targeted for July 31, 2029. This award supports fundamental research investigating the ARP2/3 complex—a critical protein assembly system essential to cellular processes including cell migration, tissue...
- Federal Project Grant Award Summary The University of Rochester received a $466,325 Project Grant from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) to acquire a Bruker Skyscan 1276 CMOS Edition high-resolution in vivo microCT imaging system. The award, obligated on May 15, 2026, with a completion date of May 14, 2027, funds the purchase and installation of this advanced imaging instrument at the Biomechanics and...
- This two-year, $219,836 National Science Foundation Integrative Activities Project Grant supports training in cryogenic electron microscopy (cryo-EM) for researchers at the University of Nebraska-Lincoln. The grant enables a research team to acquire hands-on cryo-EM training from experts at the Pacific Northwest Center for Cryo-EM, a user facility operated by Oregon Health & Science University and Pacific Northwest National Laboratory. Upon completing the training, the researchers will...
- The National Science Foundation (NSF) Office of Integrative Activities (CFDA 47.083) awarded the University of Nevada, Reno (UNR) a $170,881 Project Grant to acquire a single crystal X-ray diffractometer. This highly specialized scientific instrument supports a wide range of multidisciplinary research, including luminescent materials, bacterial communication, chemical ecology, and medicinal chemistry. The diffractometer's dual copper and molybdenum sources enable structural characterization of...
- Federal Project Grant Award Summary The National Institutes of Health (NIH) Office of the Director awarded $230,250 through the Research Infrastructure Programs (CFDA 93.351) to the University of Nebraska Medical Center for the development of transgenic mouse model resources expressing red fluorescence-based genetically encoded indicators. This two-year project, which commenced July 1, 2025 and concludes June 30, 2027, addresses critical limitations of existing green fluorescent protein...
- Federal Project Grant Award Summary The University of North Carolina at Chapel Hill received $425,494.00 in federal funding from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) to acquire a Miltenyi Ultramicroscope Blaze with Lightspeed mode, a light-sheet microscopy system designed for high-speed imaging of large cleared tissue samples at cellular resolution. The award, obligated on May 15, 2026 with a completion date of...
- The University of Illinois received a $1.5 million Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) to acquire a Bruker Avance Neo nuclear magnetic resonance (NMR) spectrometer operating at 500 megahertz proton frequency. The instrument, awarded on July 15, 2025, with completion targeted for July 14, 2026, will be equipped with an automated digital autosampler and cryogenically nitrogen-cooled...
The University of Nebraska Medical Center (UNMC) received a $565,073 Project Grant award from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) on May 15, 2026, with a completion date of May 14, 2027. The grant funds the acquisition of a Rigaku HYPIX-ARC 100 curved hybrid photon counting detector for UNMC's structural biology facility. This state-of-the-art X-ray macromolecular crystallography instrument will enable high-quality three-dimensional structural analysis of medically important biological macromolecules and their complexes. The curved detector design utilizing hybrid photon counting technology provides superior data collection capabilities, including perpendicular beam alignment to minimize reflection enlargement, expanded theta range for increased reflection collection, and enhanced measurement speed for sensitive or unstable samples compared to conventional flat detectors. The instrumentation will support research activities across 15 NIH-funded investigators at UNMC and partner institutions including the University of Nebraska-Lincoln and Creighton University. Research projects directly benefiting from the detector include studies on nucleosome assembly, ribonucleoproteins, enzyme catalysis, redox biology, cancer therapeutics, neurodegenerative disease, and infectious disease. The Research Infrastructure Programs supports such acquisitions to develop, modernize, and enhance the scientific instrumentation and shared research resources essential to advancing the biomedical research enterprise across National Institutes of Health institutes and centers.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $565.1k | 5/19/26 |