Project Grant S10OD040201
- Federal Project Grant Award Summary Yale University received a $1.98 million Project Grant from the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) awarded on August 1, 2025, for the acquisition and installation of an Orbitrap Astral mass spectrometer system to support proteomics research through the Keck Mass Spectrometry & Proteomics Resource core facility. The Orbitrap Astral represents a state-of-the-art hybrid...
- Federal Grant Award Summary Yale University received a $460,740 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025, through July 31, 2030. The award funds research to develop novel quantitative experimental and computational methods for studying continuous phenotypic transitions in cellular states. The primary deliverables include the application of Proteolysis-Targeting...
- Federal Grant Award Summary Yale University received a $669,801 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective August 1, 2025 through July 31, 2030. The award funds research into proteomic and phosphoproteomic remodeling mechanisms in aneuploid cells—cells with abnormal chromosome numbers associated with cancers and trisomic syndromes. The project leverages mass spectrometry...
- Federal Project Grant Award Summary Yale University received a $2.014 million Project Grant from the National Institute of General Medical Sciences under the Biomedical Research and Research Training program (CFDA 93.859) effective June 1, 2026, with completion targeted for May 31, 2030. The award funds development of a synthetic biology tool designed to engineer proteins with multiple posttranslational modifications (PTMs) and elucidate their binding functions. The project leverages Genomically...
- Federal Grant Award Summary Yale University received a $304,970 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective June 1, 2026 through May 31, 2031. This award funds the development of next-generation mass spectrometry (MS)-based technologies designed to directly analyze membrane protein complexes and their lipid environments with precise molecular and nanoscale spatial resolution....
- Federal Grant Award Summary Yale University received a $2.0 million Project Grant from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) to acquire and install a dedicated whole-body Positron Emission Tomography/Magnetic Resonance (PET/MR) imaging system at the Yale School of Medicine. This award, effective July 15, 2025 through July 14, 2027, supports the procurement of a time-of-flight (TOF) PET instrument integrated with...
- Federal Grant Award Summary Yale University received a $1,205,462 Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective June 10, 2025 through February 28, 2030. The award supports fundamental research investigating how biopolymers—including proteins, DNA, and RNA—alter their conformations at aqueous interfaces and how hydration structures modulate this behavior. This research...
- Federal Project Grant Award Summary Yale University received a $1.5 million Project Grant from the National Institutes of Health (NIH) Office of the Director under the Trans-NIH Research Support program (CFDA 93.310), effective September 1, 2025, through August 31, 2028. The award funds the development of a systems immunopeptidomics framework designed to investigate the role of self-peptides in regulating T cell immune responses. The research integrates next-generation mass spectrometry,...
- Federal Grant Award Summary Yale University received a $2.1 million Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), effective September 1, 2025, through August 31, 2029. The award supports fundamental research investigating the biological role and pharmacology of the EXPERA family of membrane proteins, specifically sigma-2 receptor (TMEM97) and transmembrane 6 superfamily member 2 (TM6SF2),...
- Federal Grant Award Summary Yale University received a $633,482 Project Grant from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) to acquire and install an Aurora CS cell sorting flow cytometer equipped with spectral detection capabilities. The award, dated May 15, 2026, with a completion date of May 14, 2027, supports the procurement of advanced fluorescence-based cell sorting instrumentation at Yale's New Haven,...
Yale University received a $297,269 Project Grant from the National Institutes of Health (NIH) Office of the Director under the Research Infrastructure Programs (CFDA 93.351) to acquire and implement an Olink proteogenomics instrumentation platform at the Yale Center for Genome Analysis (YCGA). The award, dated May 15, 2026, with a completion date of May 14, 2027, supports the expansion of YCGA's multiomics research capabilities by adding high-throughput, targeted proteomics analyses to its existing genomics, transcriptomics, and epigenomics service portfolio. This instrumentation addresses a critical gap in the center's offerings, enabling comprehensive systems-level investigations that integrate protein-level data with upstream genomic and transcriptomic analyses. The Olink platform will serve YCGA's extensive user base of over 1,000 NIH-funded researchers from Yale and partner institutions, providing essential proteomics services that capture dynamic biological states critical to understanding health and disease mechanisms. By leveraging Yale's existing infrastructure, personnel, and automation systems, the acquisition will enhance the center's capacity to support research across diverse biomedical disciplines and strengthen the institution's competitive positioning in securing federal research funding through advanced omics technology integration.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $297.3k | 5/7/26 |