Project Grant RF1NS142103
- This federal Project Grant award, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Drug Use and Addiction Research Programs (CFDA 93.279), is focused on developing novel methods for selectively stimulating nociceptors (pain receptors) and measuring the brain's nociceptive-specific response in both healthy individuals and those with the chronic pain condition fibromyalgia. The $2,314,276 award to Emory University will fund the creation of a new...
- This $1,049,682 federal Project Grant award from the National Institute of Neurological Disorders and Stroke, under the Drug Use and Addiction Research Programs (CFDA 93.279), will fund a 5-year prospective cohort study to develop and validate novel computational and clinical tools for understanding and addressing differences in pain experience and response to pain treatment among people with sickle cell disease (SCD). The study will utilize the Globin Research Network for Data and Discovery...
- This federal Project Grant award of $118,457.00 from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), is funded under the Drug Use and Addiction Research Programs (CFDA 93.279). The award supports research by Dr. Sylvanus Toikumo at the University of Pennsylvania to characterize the genetic architecture underlying chronic pain and addiction, with the goal of informing the development of non-addictive analgesic medications. The project aims to leverage...
- This federal Project Grant award for $667,349.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) grant program. The award is supporting research conducted by the University of Pennsylvania to investigate the role of endogenous opioid signaling and neural circuits involved in modulating pain perception and placebo analgesia. The research aims to elucidate the...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), awarded a $1,955,201 Cooperative Agreement to Cincinnati Children's Hospital Medical Center under the NIH Drug Use and Addiction Research Programs (CFDA 93.279). The 5-year award, effective September 19, 2025 through July 31, 2030, will support research to better understand the biopsychosocial determinants of pediatric-onset chronic musculoskeletal pain. The research will...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $9,237,770 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to The Washington University to conduct the "IMPETUS: Integrated Mechanisms, Phenotypes, and Translational Underpinnings of Chronic Pain After Surgery" research project. The goal is to gain integrated mechanistic insights into peripheral and central biological processes that contribute to chronic postsurgical pain...
- This Project Grant award of $4,649,740 from the National Institute of Neurological Disorders and Stroke (part of the National Institutes of Health) under the Drug Use and Addiction Research Programs (CFDA 93.279) is funding research to develop network-based models for understanding inter-individual differences in the progression of chronic musculoskeletal pain, using knee osteoarthritis as a case study. The research aims to: 1) Use natural language processing to annotate patient narratives and...
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), is funded under the Drug Use and Addiction Research Programs (CFDA 93.279). The $1,098,640 grant, awarded on September 18, 2025, supports a longitudinal research project titled "Modeling Inter-Individual Differences to Address Pain of Sickle Cell Disease (MIDAS)" at the University of Texas at Arlington (UTA). The project aims to collect...
- This Project Grant award for $668,131 was provided by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), under the Drug Use and Addiction Research Programs (CFDA 93.279). The purpose of the award is to conduct research on chronic neuropathic pain (CNP) and understand how alterations in dopamine function and reward processing may contribute to the affective symptoms of CNP. The research aims to quantify changes in dopamine release in the nucleus...
- This Project Grant award from the National Institute on Drug Abuse (CFDA 93.279 - Drug Use and Addiction Research Programs) provides $233,088 to The Washington University to investigate the role of dorsal raphe nucleus enkephalin neurons in motivational and affective behaviors during chronic pain. The primary goal is to determine how endogenous opioids in the dorsal raphe nucleus contribute to the emotional component of chronic pain states. The research will use dual-color 1-photon endoscopic...
This federal Project Grant award in the amount of $5,057,591 was provided by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health (NIH), under the Drug Use and Addiction Research Programs (CFDA 93.279). The purpose of the award is to conduct a comprehensive, prospective observational study with 2,400 emergency department patients seeking care for acute pain. The study aims to: 1) characterize clinically-informed pain phenotypes, 2) identify optimal pain treatment strategies, and 3) develop predictive models of pain trajectories and transition from acute to chronic pain. The research will leverage the emergency department setting to collect self-reported data, health records, digital physiological markers, and biological samples to holistically examine the biopsychosocial factors influencing acute pain experiences and trajectories. The 4-year project, awarded on September 12, 2025, will be conducted by the Ohio State University, a prominent public research institution.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $5.1m | 9/18/25 |