Project Grant RF1NS137980
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $2,234,191 project grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the Board of Regents of the Nevada System of Higher Education, doing business as the University of Nevada, Las Vegas (UNLV). The grant, awarded on August 15, 2025, aims to identify barriers and facilitators to Alzheimer's disease and related dementia (AD/ADRD) clinical trial participation...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant of $1,375,478 under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the J. David Gladstone Institutes in California. This grant funding supports a multidisciplinary research program to study the role of neurovascular dysfunction in neurodegeneration, CNS repair, and glial cell biology. Key research activities include in vivo two-photon and super-resolution...
- This federal Project Grant award of $2,353,206.00, issued by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the role of the SPAK-NKCC1 protein complex in the choroid plexus and its contribution to blood-CSF barrier dysfunction in vascular contributions to cognitive impairment and dementia (VCID). The research aims to fill the...
- This federal Project Grant award of $486,110 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will support advanced research at the University of Minnesota. The project aims to use cutting-edge optical imaging techniques like three-photon imaging, two-photon optogenetics, and two-photon photothrombosis to precisely map neurovascular coupling - the link between...
- This Project Grant award of $427,625 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) is funding research to develop a toolbox for studying proteome plasticity in brain endothelial cells. The research aims to further understand the mechanisms of brain blood flow regulation, which is critical for addressing neurological disorders like Alzheimer's disease where disruption of...
- This federal Project Grant award of $465,500.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant supports research focused on developing a close-loop deep brain optoacoustic stimulation system with sub-millimeter precision. The award was provided to the Trustees of Boston University, a private non-profit research university, to conduct this...
- This Project Grant award for $2,398,590.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research to investigate the role of brain microcirculation and capillary endothelial cell energetics in the development of vascular cognitive impairment and dementia (VCID) observed in Alzheimer's disease (AD) and AD-related dementias. The...
- This $2,503,949 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at Rockefeller University aimed at discovering therapeutic targets for neurological diseases. The project utilizes new techniques and concepts to study the fundamental mechanisms of brain disorders, focusing on how differences in cell-specific RNA regulation contribute to...
- This federal Project Grant award for $1,042,170.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to apply computational modeling to the analysis of intracranial recording and stimulation data from the human brain. The key objectives are to 1) dissect the neural activity patterns underlying electrophysiology recordings, and 2)...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $373,778 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Research Foundation For The State University Of New York (Stony Brook University) to establish a novel vasculature database and analytical platform for mouse brain vasculature. The project aims to develop topology-preserving vessel segmentation algorithms and advanced statistical models...
This federal Project Grant award of $2,813,759.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) grant program. The award supports research to investigate the role of the noradrenergic system and its integration with glutamatergic signaling in regulating neurovascular coupling, which is the process that increases cerebral blood flow to regions of high neuronal activity. The research aims to elucidate the physiological and pathological functions of noradrenergic neurons in neurovascular coupling, as well as how the degeneration of these neurons in Alzheimer's disease may alter neurovascular coupling. The project will be conducted by the Board of Regents of the Nevada System of Higher Education, operating through the University of Nevada, Reno, and has an award period from August 15, 2025 to July 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.8m | 8/15/25 |