Federal Grant Award Summary

The National Institute on Aging (NIA) awarded a Project Grant totaling $124,551.00 to the University of Washington on July 15, 2026, under the Aging Research program (CFDA 93.866). This five-year research initiative, with a completion date of June 30, 2031, will deliver a comprehensive epidemiological study examining the relationship between neighborhood characteristics and frailty progression in people aging with HIV. The project leverages the Centers for AIDS Research (CFAR) Network of Integrated Clinical Systems (CNICS) cohort, which encompasses clinical data from over 50,000 HIV patients across 10 U.S. sites, supplemented by geocoded residential address histories and patient-reported outcome assessments.

The research will produce three primary deliverables: a descriptive analysis of neighborhood physical and social characteristics stratified by age and frailty status among people with HIV; identification of neighborhood factors most strongly associated with frailty trajectories; and analysis of individual-level effect modifiers on neighborhood-frailty associations. By integrating rich clinical data, validated frailty measures, and neighborhood environmental data, this study will generate evidence-based insights to inform community-level interventions and prevention strategies targeting frailty progression in an aging HIV population—a demographic representing over half of the 1.2 million people living with HIV in the United States.