This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) supports research at the University of Florida to examine the contributions of cognitive load and neural activity in the anterior cingulate cortex on the coupling between the striatal and hippocampal brain networks during age-related cognitive decline. The $242,310 award will fund three years of research, from May 2024 through January 2027, to better understand normal versus pathological changes in...
This Project Grant award from the National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), will fund a research project on the relationship between daily life activity participation, cognitive function, emotional well-being, and brain health in older adults.
The $457,445 award, effective May 1, 2024 through April 30, 2026, will support a multilevel, multi-modal study using behavioral, neuroimaging, and naturalistic data collection approaches. The...
This federal Project Grant award for $798,110, funded by the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), will leverage data from the Interplay of Genes and Environments across Studies (IGEMS) Consortium to clarify modifiable risk factors for Alzheimer's disease and related dementias across the lifespan. The project aims to: (1) evaluate mid-life and late-life physical health and behavioral factors that alter dementia risk; (2) assess socioemotional...
The federal Project Grant award of $2,366,213 from the National Institute on Aging (CFDA 93.866 - Aging Research) will fund the INLIFE (Individualized Lifestyle Change for Every Aging Brain) study. The study aims to harmonize participant-level data from 12 U.S. randomized controlled trials (RCTs) with 9,570 older adults to examine how changes in lifestyle health behaviors (physical activity, cognitive activity, healthy diet, social activity) impact cognitive outcomes. Key objectives include...
This $125,847 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research program) supports research by The Leland Stanford Junior University to characterize biopsychological mismatch during cognitive training in individuals with mild cognitive impairment (MCI).
The key objective is to develop a new framework for quantifying biopsychological mismatch, measured as mental energy, task absorption, and autonomic adaptation, and examine how this mismatch relates to...
This Project Grant award, provided by the National Institute on Aging (CFDA 93.866 - Aging Research), will support a comprehensive research project to investigate the neurobiological mechanisms underlying daily life activity participation in older adults and its relationship to Alzheimer's disease pathology. The $148,568 award, with a performance period from November 2024 to January 2026, will allow Brandeis University to employ a multilevel, multimodal approach combining ecological momentary...
This National Science Foundation (NSF) Social, Behavioral, and Economic Sciences (CFDA 47.075) Project Grant award of $146,703 to Clemson University will fund research to understand how individual differences in cognitive abilities, specifically working memory and attention control, impact human performance when using automated systems. The project aims to gain a better theoretical understanding of attention control and its role in human-autonomy collaboration, as well as develop design...
This $353,391 federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to determine if a personal learning curve (PLC) cognitive assessment paradigm can detect early memory failures related to Alzheimer's disease (AD) biomarkers in a large, diverse population of older adults at risk for cognitive decline. The grant will fund research at Brigham & Women's Hospital to validate the PLC approach and assess its ability to sensitively track...
This Project Grant award from the National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), will provide $287,416 over 2 years to the University of South Carolina to investigate the association between lifestyle physical activity patterns and cognitive function in older adults at risk for Alzheimer's disease and related dementias (ADRD).
The study will leverage mobile technology to collect daily data on physical activity and cognitive performance from 84...
This $2,239,532 federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support research to examine the relationship between dispositional optimism and cognitive health outcomes, including Alzheimer's disease and related dementias. The Harvard T.H. Chan School of Public Health is the prime grantee, collaborating with sub-awardees Brigham & Women's Hospital, Rush University Medical Center, and the University of California, Davis to execute the...