Project Grant RF1AG083765
Award Date 9/1/23
Completion Date 8/31/26
Dollars Obligated $1.2M
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Illinois, USA
Similar Awards
- Federal Project Grant Award Summary Rush University Medical Center received a $1,987,698 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded July 1, 2025, with completion targeted for April 30, 2030. The grant funds research to identify molecular mechanisms linking cerebrovascular disease (CVD) pathologies to Alzheimer's disease and Alzheimer's disease-related dementias (AD/ADRD) in older adults. The research leverages clinical,...
- This Project Grant awarded by the National Institute on Aging (CFDA 93.866 - Aging Research) will provide $10,847,672 to the J. David Gladstone Institutes, a non-profit biomedical research organization, to investigate the vascular-immune mechanisms underlying cerebral amyloid angiopathy (CAA) and Alzheimer's disease pathology. The research aims to elucidate the key microglial mechanisms regulating the formation of vascular CAA versus parenchymal amyloid-beta plaques, define single-cell and...
- Federal Project Grant Award Summary Rush University Medical Center received a $431,750 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), awarded February 15, 2026, with completion targeted for January 31, 2028. The award funds a pharmacoepidemiologic study investigating the association between proton pump inhibitor (PPI) use and Alzheimer's disease and related dementias (ADRD) risk. The research leverages four ongoing U.S. studies, including...
- This Project Grant award of $437,875 from the National Institute on Aging's Aging Research program (CFDA 93.866) will fund a 2-year research project at the University of California, San Diego to quantify neurovascular protein lifetimes in the central nervous system under healthy, aging, and Alzheimer's disease conditions. The key objectives are to generate a comprehensive atlas of neurovascular protein lifetimes and identify changes associated with aging and Alzheimer's disease. The project will...
- Federal Project Grant Summary The National Institute on Aging (NIA) awarded New York University School of Medicine a $3.104 million Project Grant on September 15, 2025, under the Aging Research program (CFDA 93.866) to investigate the relationship between peripheral immune dysfunction and vascular contributions to cognitive decline and dementia. The research integrates blood biomarker analysis—specifically measuring platelet aggregation, neutrophil activity, and proteomic data—with advanced...
- This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) totaling $2,317,887 will be used by Indiana University Indianapolis to map paravascular cerebrospinal fluid (PCSF) signatures associated with healthy aging, aging with hypertension, and Alzheimer's disease (AD). The researchers will leverage dynamic diffusion-weighted imaging, a novel neuroimaging technique, to quantify PCSF dynamics and volume near major arteries - a key component of the glymphatic...
- This $427,625 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) aims to elucidate the mechanisms by which microgliopathy, a genetic neurological disorder, causes early-onset dementia. The research will investigate how the loss of the DAP12 protein in microglia, the immune cells of the brain, leads to heightened signaling of the RUNX and STAT3 pathways. This dysregulation is hypothesized to disrupt normal microglial functions and induce brain pathology and...
- The National Institute on Aging awarded a $1,931,965 Project Grant (CFDA 93.866 - Aging Research) to the Regenerative Research Foundation, a non-profit organization in Albany, New York. The purpose of this federal grant is to develop and validate a novel human induced pluripotent stem cell (iPSC) model that incorporates cerebral cortical neurons, glia, vascular endothelial cells, and microglia to study cerebrovascular interactions in Alzheimer's disease-related dementias (ADRD). The R61 phase of...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded Henry Ford Health + Michigan State University Health Sciences a Project Grant totaling $3,062,355 under the Aging Research program (CFDA 93.866) to advance understanding of cerebral waste clearance mechanisms during Alzheimer's disease progression. The research initiative, spanning from September 15, 2025 through August 31, 2029, will optimize and validate detection of microvessels within the cerebral vascular,...
- Grant Award Summary The University of Pittsburgh received a $2.003 million Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) effective September 15, 2025, through August 31, 2029. The award supports research investigating white matter injury in Alzheimer's disease (AD), specifically examining risk factors and consequences of white matter injury in brain regions affected by AD pathology. The research employs a novel measurement methodology called...