This Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) in the amount of $2,433,859 supports research at The Johns Hopkins University to investigate age-related hearing loss and cognitive decline. The key objectives are to study the molecular, cellular, and connectivity changes in the central auditory system during normal aging and Alzheimer's disease, with the goal of developing targeted therapeutic strategies. The research integrates single-cell sequencing, connectomics, and in vivo imaging to identify vulnerable cell types and circuit dysfunctions, and also explores whether auditory training can reverse some age-related changes. This 3-year award, with a start date of September 1, 2023, aims to advance the understanding of how aging and Alzheimer's impact the central auditory system and cognitive function, laying the groundwork for future interventions to address age-related hearing loss and cognitive decline.
Generated 7/16/24, 9:16 AM